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Results for “Pharmacodynamics Study”

6,595 trials

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Showing 20 of 6,595 results

Early research (Phase 1)Study completedNCT01579149
What this trial is testing

A Phase I Dose Escalation Study of Plerixafor in Healthy Subjects of Japanese Descent

Who this might be right for
Healthy Volunteer
Genzyme, a Sanofi Company 24
Early research (Phase 1)Study completedNCT00697632
What this trial is testing

Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies

Who this might be right for
Advanced Cancer
Mirati Therapeutics Inc. 180
Early research (Phase 1)Study completedNCT03773835
What this trial is testing

A Study Evaluating Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Single IV Dose of HSK3486 Injectable Emulsion in Healthy Subjects.

Who this might be right for
AnesthesiaSedation
Sichuan Haisco Pharmaceutical Group Co., Ltd 24
Early research (Phase 1)Looking for participantsNCT07399678
What this trial is testing

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

Who this might be right for
Overweight or Obese AdultsOverweight or Obese, Type 2 Diabetes
Alveus Therapeutics, Inc. 180
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07154485
What this trial is testing

Investigator Initiated Study for the Safety and Efficacy in Frontotemporal Dementia

Who this might be right for
Dementia Frontotemporal
Hee-Jin Kim 15
Early research (Phase 1)Study completedNCT05343715
What this trial is testing

PK/PD Study of 2 Agalsidase Formulations in Single Dose of 1 mg/kg Administered to Healthy Volunteers as IV Infusion

Who this might be right for
Fabry Disease
Bio Sidus SA 24
Early research (Phase 1)Study completedNCT04478708
What this trial is testing

Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity

Who this might be right for
Obesity
Amgen 110
Early research (Phase 1)Study completedNCT02039817
What this trial is testing

PK and PD Study of IDN-6556 in Subjects With Severe Renal Impairment and Matched Healthy Volunteers

Who this might be right for
Renal ImpairmentRenal InsufficiencyKidney Disease+1 more
Conatus Pharmaceuticals Inc. 16
Early research (Phase 1)Study completedNCT01138033
What this trial is testing

Study of a Focal Adhesion Kinase Inhibitor in Subjects With Solid Tumors

Who this might be right for
Cancer
GlaxoSmithKline 74
Testing effectiveness (Phase 2)Looking for participantsNCT07143448
What this trial is testing

HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults

Who this might be right for
Pulmonary Arterial Hypertension
35Pharma Inc 90
Early research (Phase 1)Study completedNCT02532998
What this trial is testing

Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects

Who this might be right for
PharmacodynamicsHealthy Subjects
AstraZeneca 40
Early research (Phase 1)Study completedNCT03976687
What this trial is testing

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EYP001a in Healthy Volunteers and Nonalcoholic Steatohepatitis Patients

Who this might be right for
NASH - Nonalcoholic SteatohepatitisHealthy
Enyo Pharma 16
Testing effectiveness (Phase 2)Study completedNCT03834948
What this trial is testing

AO-176 in Multiple Solid Tumor Malignancies

Who this might be right for
Solid Tumor
Arch Oncology 57
Post-approval studies (Phase 4)Looking for participantsNCT07142343
What this trial is testing

Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) Disease

Who this might be right for
CHAPLE Disease
Regeneron Pharmaceuticals 5
Testing effectiveness (Phase 2)Study completedNCT02807363
What this trial is testing

Pharmacokinetic/Pharmacodynamic Profile of Orally Administered Leuprolide in Healthy Female Volunteers

Who this might be right for
Endometriosis
Enteris BioPharma Inc. 35
Early research (Phase 1)Study completedNCT05225584
What this trial is testing

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

Who this might be right for
Non Hodgkin Lymphoma (NHL)Peripheral T-cell Lymphoma (PTCL)Cutaneous T-Cell Lymphoma (CTCL)+3 more
Kymera Therapeutics, Inc. 56
Early research (Phase 1)Study completedNCT01899755
What this trial is testing

Evaluate the Pharmacokinetics (PK), Safety and Tolerability, Immunogenicity, and Pharmacodynamics (PD) of GSK2800528 in Healthy Subjects.

Who this might be right for
Psoriasis
GlaxoSmithKline 45
Early research (Phase 1)Not Yet RecruitingNCT07399899
What this trial is testing

Dose-Finding Study of NBX-100 in Healthy Adult Participants

Who this might be right for
Healthy Participants
Neurala Biosciences 8
Early research (Phase 1)Study completedNCT06933043
What this trial is testing

A Study on the Safety, Tolerability, Bioavailability and Mechanism of Action of Intravenous NAV-240 in Adults.

Who this might be right for
Healthy Volunteers
Navigator Medicines, Inc. 24
Early research (Phase 1)Study completedNCT04052971
What this trial is testing

To Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of ABN401 in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer Harboring c-MET Dysregulation

Who this might be right for
Advanced Solid Tumors
Abion Inc 24
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