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Results for “Pharmacokinetics of Methotrexate”

88 trials

Showing 20 of 88 results

Large-scale testing (Phase 3)Study completedNCT01895309
What this trial is testing

A Study Comparing SB4 to Enbrel® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy

Who this might be right for
Rheumatoid Arthritis
Samsung Bioepis Co., Ltd. 596
Early research (Phase 1)Study completedNCT00634504
What this trial is testing

Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze

Who this might be right for
OsteosarcomaLeukemiaLymphoma
BTG International Inc. 20
Early research (Phase 1)Study completedNCT01745055
What this trial is testing

Co-Administration Of Methotrexate And CP-690,550

Who this might be right for
Rheumatoid Arthritis
Pfizer 12
Early research (Phase 1)Study completedNCT00989703
What this trial is testing

GLPG0259 Multiple Ascending Dose and Methotrexate Drug-drug Interaction (DDI) in Healthy Subjects

Who this might be right for
Healthy
Galapagos NV 24
Early research (Phase 1)Study completedNCT01754805
What this trial is testing

A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Methotrexate in Patients With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Astellas Pharma Inc 15
Testing effectiveness (Phase 2)Ended earlyNCT01716039
What this trial is testing

Pharmacokinetics of Adalimumab With Methotrexate for Treatment of Patients With Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Alimentiv Inc. 22
Testing effectiveness (Phase 2)Study completedNCT01009242
What this trial is testing

To Evaluate the Blood Levels and Safety of IV and Subcutaneous CDP6038 in Subjects With Rheumatoid Arthritis Using Methotrexate

Who this might be right for
ArthritisRheumatoid Arthritis
UCB Pharma 40
Early research (Phase 1)Study completedNCT02171143
What this trial is testing

A Dose Escalation Study to Assess Safety, Tolerability and Pharmacokinetics of ASP2409 Following a Single Intravenous Dose in Patients With Rheumatoid Arthritis on Methotrexate

Who this might be right for
Rheumatoid ArthritisPharmacokinetics of ASP2409
Astellas Pharma Global Development, Inc. 58
Early research (Phase 1)Study completedNCT02456844
What this trial is testing

Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients

Who this might be right for
Rheumatoid Arthritis
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT01442545
What this trial is testing

Investigate How JNJ-39758979 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants

Who this might be right for
Rheumatoid Arthritis
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 21
Early research (Phase 1)Active Not RecruitingNCT06541665
What this trial is testing

Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined ONO-4059 and R-MPV Therapy for PCNSL

Who this might be right for
Primary Central Nervous System Lymphoma
Ono Pharmaceutical Co., Ltd. 20
Early research (Phase 1)Ended earlyNCT01390441
What this trial is testing

The Pharmacokinetics and Safety of MK-8808 (MK-8808-002)

Who this might be right for
Rheumatoid Arthritis
Merck Sharp & Dohme LLC 100
Early research (Phase 1)Study completedNCT01741493
What this trial is testing

A Study in Healthy Adults and Adult Subjects With Rheumatoid Arthritis to Evaluate the Safety, Tolerability and Pharmacokinetics After Multiple Doses of ABT-494

Who this might be right for
Rheumatoid Arthritis
AbbVie (prior sponsor, Abbott) 67
Early research (Phase 1)Study completedNCT00365001
What this trial is testing

A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis.

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 23
Testing effectiveness (Phase 2)Study completedNCT05279417
What this trial is testing

ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA)

Who this might be right for
Rheumatoid Arthritis
Aclaris Therapeutics, Inc. 251
Testing effectiveness (Phase 2)Study completedNCT01404585
What this trial is testing

Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Bristol-Myers Squibb 123
Early research (Phase 1)UnknownNCT04179513
What this trial is testing

Evaluate the Safety and Tolerability of Multiple Doses of Gerilimzumab in Rheumatoid Arthritis Patients

Who this might be right for
Rheumatoid Arthritis
Genor Biopharma Co., Ltd. 24
Testing effectiveness (Phase 2)WithdrawnNCT02097264
What this trial is testing

A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Who this might be right for
InflammationRheumatoid Arthritis
Novo Nordisk A/S
Testing effectiveness (Phase 2)Study completedNCT04577781
What this trial is testing

A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 6 Weeks in Adults With Moderately to Severely Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Who this might be right for
Rheumatoid Arthritis
Galapagos NV 28
Large-scale testing (Phase 3)Study completedNCT02277444
What this trial is testing

Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy

Who this might be right for
Arthritis, Juvenile
Janssen Research & Development, LLC 130
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