Early research (Phase 1)WithdrawnNCT04371640What this trial is testingSirolimus in COVID-19 Phase 1Who this might be right forSARS-CoV-2Covid-19 Walter K. Kraft
Post-approval studies (Phase 4)UnknownNCT04993872What this trial is testingPharmacokinetics of Calcineurin & mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BIC/FTC/TAFWho this might be right forHIV-infected Patient Kidney Transplant Recipient Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba 5
Post-approval studies (Phase 4)Study completedNCT00223028What this trial is testingInvestigation of the Steady State Pharmacokinetics of Sirolimus, Mycophenolat Mofetil and Fluvastatin After Renal TransplantationWho this might be right forRenal Transplantation University Hospital Schleswig-Holstein 15
Testing effectiveness (Phase 2)Looking for participantsNCT06727305What this trial is testingMTOR Inhibitors in Older AdultsWho this might be right forAging University of Texas Southwestern Medical Center 60
Post-approval studies (Phase 4)UnknownNCT00166816What this trial is testingThe Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant PatientsWho this might be right forTransplantationKidney TransplantationImmunosuppression National Taiwan University Hospital 40
Early research (Phase 1)Study completedNCT01809860What this trial is testingEvaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy SubjectsWho this might be right forHealthy SubjectsPharmacokinetics of IsavuconazolePharmacokinetics of Sirolimus Astellas Pharma Global Development, Inc. 22
Post-approval studies (Phase 4)UnknownNCT00166829What this trial is testingThe Effect of Sirolimus on the Pharmacokinetics of TacrolimusWho this might be right forKidney Transplantation National Taiwan University Hospital 40
Early research (Phase 1)Study completedNCT00003712What this trial is testingCCI-779 in Treating Patients With Advanced Solid TumorsWho this might be right forBrain and Central Nervous System TumorsMetastatic CancerUnspecified Adult Solid Tumor, Protocol Specific The University of Texas Health Science Center at San Antonio 15
Large-scale testing (Phase 3)Ended earlyNCT01709136What this trial is testingPharmacokinetics of Sirolimus and Tacrolimus in Liver Transplant Recipients With Tacrolimus ToxicityWho this might be right forHypertension University of Pittsburgh 3
Testing effectiveness (Phase 2)Study completedNCT00494091What this trial is testingStudy Evaluating The Safety, Efficacy & Pharmacokinetics Of Temsirolimus(CCI-779) In Subjects With Advanced Renal Cell CarcinomaWho this might be right forAdvanced Renal Cell Carcinoma Pfizer 82
Early research (Phase 1)Study completedNCT01337765What this trial is testingSafety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor PatientsWho this might be right forUnspecified Adult Solid Tumor, Protocol SpecificSolid Tumor Pfizer 29
Testing effectiveness (Phase 2)Study completedNCT01177397What this trial is testingStudy to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple MyelomaWho this might be right forMultiple MyelomaDiffuse Large B-Cell LymphomaGlioblastoma Multiforme+4 more Celgene 226
Early research (Phase 1)Ended earlyNCT01347866What this trial is testingClinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced CancerWho this might be right forAdvanced Cancer Pfizer 105
Not applicableStudy completedNCT00352547What this trial is testingInfluence of Genes on Sirolimus Metabolism in Patients With Kidney TransplantationWho this might be right forRenal Transplant National Institutes of Health Clinical Center (CC) 93
Early research (Phase 1)Study completedNCT00780104What this trial is testingSirolimus in Combination With MEC in High Risk Myeloid LeukemiasWho this might be right forMyeloid LeukemiasAMLLeukemia+1 more Abramson Cancer Center at Penn Medicine 16
Early research (Phase 1)Study completedNCT00999882What this trial is testingSafety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer PatientsWho this might be right forCancerAdvanced Hepatocellular Carcinoma AstraZeneca 26
Early research (Phase 1)WithdrawnNCT01182883What this trial is testingA Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid TumorsWho this might be right forBrain Stem NeoplasmsGliomaPinealoma National Cancer Institute (NCI)
Early research (Phase 1)WithdrawnNCT01194193What this trial is testingPreliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced TumoursWho this might be right forCancerAdvanced Solid TumoursLymphomas AstraZeneca 63
Early research (Phase 1)Study completedNCT01545947What this trial is testingStudy Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung CancerWho this might be right forCarcinoma, Non-Small-Cell LungNon-Small Cell Lung Cancer Celgene 76
Early research (Phase 1)Study completedNCT01236378What this trial is testingStudy To Evaluate Pharmacokinetics Of Sirolimus In Stable Renal Transplant RecipientsWho this might be right forTransplant RejectionRenal Transplantation Pfizer 24