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Results for “Pharmacokinetics of Sirolimus”

31 trials

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Showing 20 of 31 results

Early research (Phase 1)Study completedNCT00999882
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients

Who this might be right for
CancerAdvanced Hepatocellular Carcinoma
AstraZeneca 26
Early research (Phase 1)Study completedNCT01809860
What this trial is testing

Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects

Who this might be right for
Healthy SubjectsPharmacokinetics of IsavuconazolePharmacokinetics of Sirolimus
Astellas Pharma Global Development, Inc. 22
Early research (Phase 1)WithdrawnNCT01182883
What this trial is testing

A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Brain Stem NeoplasmsGliomaPinealoma
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT00780104
What this trial is testing

Sirolimus in Combination With MEC in High Risk Myeloid Leukemias

Who this might be right for
Myeloid LeukemiasAMLLeukemia+1 more
Abramson Cancer Center at Penn Medicine 16
Post-approval studies (Phase 4)UnknownNCT00166829
What this trial is testing

The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus

Who this might be right for
Kidney Transplantation
National Taiwan University Hospital 40
Early research (Phase 1)Study completedNCT01353625
What this trial is testing

Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.

Who this might be right for
Glioblastoma MultiformeSquamous Cell Carcinoma of Head and NeckProstate Cancer+3 more
Celgene 118
Post-approval studies (Phase 4)UnknownNCT00166842
What this trial is testing

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Who this might be right for
TransplantationKidney TransplantationImmunosuppression
National Taiwan University Hospital 40
Early research (Phase 1)Ended earlyNCT01347866
What this trial is testing

Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer

Who this might be right for
Advanced Cancer
Pfizer 105
Testing effectiveness (Phase 2)Study completedNCT03522298
What this trial is testing

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Who this might be right for
Glioblastoma, Adult
Kazia Therapeutics Limited 30
Testing effectiveness (Phase 2)UnknownNCT00390195
What this trial is testing

Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
National Health Research Institutes, Taiwan 134
Post-approval studies (Phase 4)UnknownNCT04993872
What this trial is testing

Pharmacokinetics of Calcineurin & mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BIC/FTC/TAF

Who this might be right for
HIV-infected Patient Kidney Transplant Recipient
Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba 5
Large-scale testing (Phase 3)Looking for participantsNCT05643872
What this trial is testing

A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita

Who this might be right for
Pachyonychia Congenita
Palvella Therapeutics, Inc. 45
Early research (Phase 1)Study completedNCT01079286
What this trial is testing

Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers

Who this might be right for
Renal Cell CancerCancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 18
Not applicableStudy completedNCT00352547
What this trial is testing

Influence of Genes on Sirolimus Metabolism in Patients With Kidney Transplantation

Who this might be right for
Renal Transplant
National Institutes of Health Clinical Center (CC) 93
Early research (Phase 1)Study completedNCT00927823
What this trial is testing

A Trial To Assess Safety And Tolerability Of PF-04691502 In Cancer Patients

Who this might be right for
Cancer
Pfizer 37
Early research (Phase 1)Looking for participantsNCT05661461
What this trial is testing

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Who this might be right for
Tumor, SolidTumorAdvanced Solid Tumor
Aadi Bioscience, Inc. 28
Early research (Phase 1)Study completedNCT01545947
What this trial is testing

Study Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell LungNon-Small Cell Lung Cancer
Celgene 76
Early research (Phase 1)Study completedNCT03730142
What this trial is testing

WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Advanced Cancer
Shanghai Jiatan Pharmatech Co., Ltd 82
Testing effectiveness (Phase 2)Study completedNCT01177397
What this trial is testing

Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma

Who this might be right for
Multiple MyelomaDiffuse Large B-Cell LymphomaGlioblastoma Multiforme+4 more
Celgene 226
Early research (Phase 1)Study completedNCT00003712
What this trial is testing

CCI-779 in Treating Patients With Advanced Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsMetastatic CancerUnspecified Adult Solid Tumor, Protocol Specific
The University of Texas Health Science Center at San Antonio 15
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