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Results for “Pharmacokinetics of Sirolimus”

31 trials

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Showing 20 of 31 results

Early research (Phase 1)Looking for participantsNCT05661461
What this trial is testing

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Who this might be right for
Tumor, SolidTumorAdvanced Solid Tumor
Aadi Bioscience, Inc. 28
Not applicableStudy completedNCT00352547
What this trial is testing

Influence of Genes on Sirolimus Metabolism in Patients With Kidney Transplantation

Who this might be right for
Renal Transplant
National Institutes of Health Clinical Center (CC) 93
Early research (Phase 1)Study completedNCT01337765
What this trial is testing

Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients

Who this might be right for
Unspecified Adult Solid Tumor, Protocol SpecificSolid Tumor
Pfizer 29
Early research (Phase 1)Study completedNCT01026402
What this trial is testing

Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of AZD2014

Who this might be right for
Advanced Solid Malignancies
AstraZeneca 172
Post-approval studies (Phase 4)UnknownNCT00166829
What this trial is testing

The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus

Who this might be right for
Kidney Transplantation
National Taiwan University Hospital 40
Early research (Phase 1)Study completedNCT01809860
What this trial is testing

Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects

Who this might be right for
Healthy SubjectsPharmacokinetics of IsavuconazolePharmacokinetics of Sirolimus
Astellas Pharma Global Development, Inc. 22
Large-scale testing (Phase 3)Ended earlyNCT01709136
What this trial is testing

Pharmacokinetics of Sirolimus and Tacrolimus in Liver Transplant Recipients With Tacrolimus Toxicity

Who this might be right for
Hypertension
University of Pittsburgh 3
Early research (Phase 1)WithdrawnNCT01182883
What this trial is testing

A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Brain Stem NeoplasmsGliomaPinealoma
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT03522298
What this trial is testing

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Who this might be right for
Glioblastoma, Adult
Kazia Therapeutics Limited 30
Early research (Phase 1)WithdrawnNCT01194193
What this trial is testing

Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours

Who this might be right for
CancerAdvanced Solid TumoursLymphomas
AstraZeneca 63
Testing effectiveness (Phase 2)Study completedNCT00494091
What this trial is testing

Study Evaluating The Safety, Efficacy & Pharmacokinetics Of Temsirolimus(CCI-779) In Subjects With Advanced Renal Cell Carcinoma

Who this might be right for
Advanced Renal Cell Carcinoma
Pfizer 82
Early research (Phase 1)Study completedNCT01236378
What this trial is testing

Study To Evaluate Pharmacokinetics Of Sirolimus In Stable Renal Transplant Recipients

Who this might be right for
Transplant RejectionRenal Transplantation
Pfizer 24
Early research (Phase 1)Study completedNCT00999882
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients

Who this might be right for
CancerAdvanced Hepatocellular Carcinoma
AstraZeneca 26
Testing effectiveness (Phase 2)Study completedNCT01177397
What this trial is testing

Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma

Who this might be right for
Multiple MyelomaDiffuse Large B-Cell LymphomaGlioblastoma Multiforme+4 more
Celgene 226
Early research (Phase 1)Study completedNCT00927823
What this trial is testing

A Trial To Assess Safety And Tolerability Of PF-04691502 In Cancer Patients

Who this might be right for
Cancer
Pfizer 37
Early research (Phase 1)Study completedNCT01079286
What this trial is testing

Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers

Who this might be right for
Renal Cell CancerCancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 18
Post-approval studies (Phase 4)UnknownNCT00166816
What this trial is testing

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

Who this might be right for
TransplantationKidney TransplantationImmunosuppression
National Taiwan University Hospital 40
Testing effectiveness (Phase 2)UnknownNCT00390195
What this trial is testing

Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
National Health Research Institutes, Taiwan 134
Early research (Phase 1)Ended earlyNCT01347866
What this trial is testing

Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer

Who this might be right for
Advanced Cancer
Pfizer 105
Post-approval studies (Phase 4)UnknownNCT04993872
What this trial is testing

Pharmacokinetics of Calcineurin & mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BIC/FTC/TAF

Who this might be right for
HIV-infected Patient Kidney Transplant Recipient
Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba 5
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