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Results for “Phase 1: Advanced or Refractory Solid Tumours”

223 trials

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Showing 20 of 223 results

Early research (Phase 1)Looking for participantsNCT07182149
What this trial is testing

NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

Who this might be right for
HNSCCESCCEsophageal Adenocarcinoma+7 more
Normunity AccelCo, Inc. 150
Early research (Phase 1)Study completedNCT00084708
What this trial is testing

Calcitriol and Gefitinib With or Without Dexamethasone in Treating Patients With Advanced Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Roswell Park Cancer Institute 53
Early research (Phase 1)Ended earlyNCT04795713
What this trial is testing

Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1

Who this might be right for
Advanced Solid TumorNon-small Cell Lung CancerSquamous Cell Carcinoma of Head and Neck
Molecular Templates, Inc. 64
Early research (Phase 1)Study completedNCT00607724
What this trial is testing

GDC-0449 in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Genentech, Inc. 68
Early research (Phase 1)Study completedNCT03017833
What this trial is testing

Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm+1 more
M.D. Anderson Cancer Center 31
Early research (Phase 1)Study completedNCT02159989
What this trial is testing

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmFibrolamellar CarcinomaMetastatic Malignant Solid Neoplasm+5 more
National Cancer Institute (NCI) 83
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Early research (Phase 1)Study completedNCT00646139
What this trial is testing

KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment

Who this might be right for
LymphomaLymphoproliferative DisorderSmall Intestine Cancer+1 more
Roswell Park Cancer Institute 7
Early research (Phase 1)Study completedNCT05564806
What this trial is testing

Study of YH004 (4-1BB Agonist Antibody) in Advanced Solid Tumors And Relapsed Or Refractory Non-Hodgkin Lymphoma

Who this might be right for
Advanced Solid TumorsRelapsed Or Refractory Non-Hodgkin Lymphoma
Eucure (Beijing) Biopharma Co., Ltd 9
Early research (Phase 1)Study completedNCT00004065
What this trial is testing

Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+9 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT00060645
What this trial is testing

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 33
Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Early research (Phase 1)WithdrawnNCT06372574
What this trial is testing

RO7617991 in Patients With Locally Advanced or Metastatic MAGE-A4-Positive Solid Tumors

Who this might be right for
Refractory CancerRecurrent CancerSolid Tumor, Adult
Genentech, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT03648372
What this trial is testing

TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System

Who this might be right for
NeoplasmsLymphomaHematologic Neoplasms
Takeda 109
Early research (Phase 1)Ended earlyNCT05274451
What this trial is testing

Investigate LYL797 in Adults With Solid Tumors

Who this might be right for
Triple Negative Breast CancerTNBC - Triple-Negative Breast CancerNon-small Cell Lung Cancer+20 more
Lyell Immunopharma, Inc. 57
Early research (Phase 1)Study completedNCT00287937
What this trial is testing

Vorinostat, Paclitaxel, and Carboplatin in Treating Patients With Advanced or Refractory Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00193570
What this trial is testing

Topotecan in Combination With Docetaxel in Refractory and/or Advanced Solid Tumors

Who this might be right for
Cancer
SCRI Development Innovations, LLC 20
Early research (Phase 1)Study completedNCT00275080
What this trial is testing

Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+48 more
National Cancer Institute (NCI) 80
Early research (Phase 1)Study completedNCT03941262
What this trial is testing

Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy

Who this might be right for
Refractory CancerMetastatic CancerRecurrent Cancer+4 more
NKGen Biotech, Inc. 27
Early research (Phase 1)Study completedNCT00014261
What this trial is testing

Temozolomide Plus PEG-Interferon Alfa-2B in Treating Patients With Advanced Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Dartmouth-Hitchcock Medical Center
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