Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Phase 1: Advanced or Refractory Solid Tumours”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Ended earlyNCT03065387
What this trial is testing

Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

Who this might be right for
Advanced Malignant Solid NeoplasmEGFR Gene AmplificationEGFR Gene Mutation+7 more
M.D. Anderson Cancer Center 84
Early research (Phase 1)Ended earlyNCT02110563
What this trial is testing

Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or Lymphoma

Who this might be right for
Solid TumorsMultiple MyelomaNon-Hodgkins Lymphoma+3 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 50
Early research (Phase 1)Study completedNCT04742556
What this trial is testing

Test Different Doses of BI 3011441 in Japanese People With Different Types of Advanced Cancer (NRAS/KRAS Mutation Positive)

Who this might be right for
Solid Tumors, KRAS Mutation
Boehringer Ingelheim 15
Early research (Phase 1)Study completedNCT00003004
What this trial is testing

Combination Chemotherapy in Treating Patients With Refractory or Recurrent Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center 73
Early research (Phase 1)Study completedNCT03430882
What this trial is testing

Sapanisertib, Carboplatin, and Paclitaxel in Treating Patients With Recurrent or Refractory Malignant Solid Tumors

Who this might be right for
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid Neoplasm
M.D. Anderson Cancer Center 35
Early research (Phase 1)Study completedNCT01976741
What this trial is testing

Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)

Who this might be right for
Neoplasms
Bayer 168
Testing effectiveness (Phase 2)Ended earlyNCT03323398
What this trial is testing

Dose Escalation and Efficacy Study of mRNA-2416 for Intratumoral Injection Alone and in Combination With Durvalumab for Participants With Advanced Malignancies

Who this might be right for
Relapsed/Refractory Solid Tumor Malignancies or LymphomaOvarian Cancer
ModernaTX, Inc. 79
Early research (Phase 1)Study completedNCT00060632
What this trial is testing

Safety Study of Ridaforolimus in Patients With Advanced, Refractory or Recurrent Malignancies (MK-8669-001 AM5)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 46
Early research (Phase 1)Looking for participantsNCT04777994
What this trial is testing

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
Advanced Solid Tumor Cancer
Calico Life Sciences LLC 248
Testing effectiveness (Phase 2)Study completedNCT01675128
What this trial is testing

ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer

Who this might be right for
Colorectal NeoplasmsColorectal CarcinomaColorectal Tumors
National Cancer Institute (NCI) 24
Early research (Phase 1)Study completedNCT01585870
What this trial is testing

Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of Sorafenib and Eribulin in Combination

Who this might be right for
Neoplasms
Bayer 40
Testing effectiveness (Phase 2)Looking for participantsNCT05669430
What this trial is testing

GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

Who this might be right for
Solid Tumor, AdultRefractory CancerEndometrial Carcinoma (EC)+4 more
GV20 Therapeutics 365
Early research (Phase 1)Study completedNCT00633269
What this trial is testing

Study Assessing Metabolism, Excretion and Pharmacokinetics of a Poly (ADP-Ribose) Polymerase (PARP) Inhibitor in Patients With Solid Metastatic Tumours

Who this might be right for
Neoplasm Metastasis
AstraZeneca 6
Early research (Phase 1)Ended earlyNCT02408861
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmAnal CarcinomaHIV Infection+7 more
National Cancer Institute (NCI) 79
Early research (Phase 1)Study completedNCT02451553
What this trial is testing

Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmBile Duct CarcinomaRecurrent Malignant Solid Neoplasm+4 more
University of Washington 41
Early research (Phase 1)Active Not RecruitingNCT01552356
What this trial is testing

Pazopanib Hydrochloride in Treating Patients With Advanced or Refractory Solid Tumors

Who this might be right for
Solid Neoplasm
National Cancer Institute (NCI) 54
Early research (Phase 1)Study completedNCT00193583
What this trial is testing

Weekly Topotecan in Combination With Carboplatin in Two Different Schedules for Refractory and/or Advanced Solid Tumors

Who this might be right for
Cancer
SCRI Development Innovations, LLC 18
Early research (Phase 1)Study completedNCT02743637
What this trial is testing

A Dose Escalation Study of SDX-7320 in Patients With Advanced Refractory or Late-Stage Solid Tumors

Who this might be right for
Advanced MalignancyAdvanced Solid TumorsNeoplasm+1 more
SynDevRx, Inc. 32
Early research (Phase 1)Study completedNCT04676633
What this trial is testing

Safety, Tolerability, PK, Anti-Tumor Activity of STP705 in Subjects With Advanced/Metastatic or Surgically Unresectable Solid Tumors Who Are Refractory to Standard Therapy

Who this might be right for
Hepatocellular CarcinomaLiver MetastasesCholangiocarcinoma
Sirnaomics 5
Testing effectiveness (Phase 2)Study completedNCT01861496
What this trial is testing

Phase I/II Study to Evaluate the Safety and Tolerability of LiPlaCis in Patients With Advanced or Refractory Tumours

Who this might be right for
Phase 1: Advanced or Refractory Solid TumoursPhase 2 Part: Metastatic Breast Cancer, Prostate Cancer and Skin Cancer
Allarity Therapeutics 50
Next Page