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Results for “Philadelphia Chromosome Negative Adult B-cell Acute Lymphoblastic Leukemia”

53 trials

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Showing 20 of 53 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05453500
What this trial is testing

Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
University of Washington 32
Testing effectiveness (Phase 2)Study completedNCT00787761
What this trial is testing

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Who this might be right for
Myeloproliferative DisordersKidney CancerLeukemia+4 more
Northside Hospital, Inc. 24
Large-scale testing (Phase 3)UnknownNCT03564470
What this trial is testing

Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL

Who this might be right for
LeukemiaLeukemia, AcuteLeukemia, Lymphoblastic+1 more
Nanfang Hospital, Southern Medical University 120
Testing effectiveness (Phase 2)Study completedNCT01475058
What this trial is testing

CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant

Who this might be right for
Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic LeukemiaPhiladelphia Chromosome Positive Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia+4 more
Fred Hutchinson Cancer Center 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT07199855
What this trial is testing

Blinatumomab Combined With Venetoclax as Maintenance Therapy After Allo-HSCT in High-risk Ph Negative Acute B-cell Lymphoblastic Leukemia

Who this might be right for
B-Cell Acute Lymphoblastic Leukemia, Adult
Zhejiang University 24
Large-scale testing (Phase 3)Ended earlyNCT04817761
What this trial is testing

SPARK-ALL: Calaspargase Pegol in Adults With ALL

Who this might be right for
Acute Lymphoblastic Leukemia
Institut de Recherches Internationales Servier 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT01424982
What this trial is testing

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAdult Acute Lymphoblastic Leukemia in Complete Remission+4 more
M.D. Anderson Cancer Center 88
Testing effectiveness (Phase 2)UnknownNCT04740203
What this trial is testing

Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph- B-ALL

Who this might be right for
B-Cell Acute Lymphoblastic Leukemia, Adult
Zhejiang University 50
Testing effectiveness (Phase 2)UnknownNCT00008307
What this trial is testing

Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
Herbert Irving Comprehensive Cancer Center 52
Testing effectiveness (Phase 2)Study completedNCT02484430
What this trial is testing

Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative+3 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Study completedNCT01427881
What this trial is testing

Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Megakaryoblastic Leukemia (M7)+65 more
Fred Hutchinson Cancer Center 43
Early research (Phase 1)Looking for participantsNCT06287528
What this trial is testing

19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia-Negative ALLPhiladelphia-Positive ALLRelapsed ALL, Adult+3 more
Memorial Sloan Kettering Cancer Center 18
Testing effectiveness (Phase 2)Study completedNCT00036738
What this trial is testing

Fludarabine Phosphate and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Has Responded to Treatment With Imatinib Mesylate, Dasatinib, or Nilotinib

Who this might be right for
Adult Acute Lymphoblastic Leukemia in RemissionAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Blastic Phase+7 more
Fred Hutchinson Cancer Center 28
Not applicableStudy completedNCT00068523
What this trial is testing

Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+3 more
Case Comprehensive Cancer Center 10
Large-scale testing (Phase 3)Active Not RecruitingNCT02003222
What this trial is testing

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
National Cancer Institute (NCI) 488
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06930105
What this trial is testing

Impact of Low-intensity Chemotherapy Combined With Short-course Blinatumomab on Allo-HSCT in Adults With Ph- B-ALL

Who this might be right for
Acute Lymphoid Leukemia (ALL)
Xianmin Song, MD 45
Testing effectiveness (Phase 2)Study completedNCT00458848
What this trial is testing

Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 470
Testing effectiveness (Phase 2)Study completedNCT03367299
What this trial is testing

Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoid LeukemiaPhiladelphia Chromosome-Negative B-Cell Precursor
Gruppo Italiano Malattie EMatologiche dell'Adulto 149
Testing effectiveness (Phase 2)Looking for participantsNCT03739814
What this trial is testing

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeRecurrent B Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 84
Not applicableLooking for participantsNCT06481241
What this trial is testing

Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL

Who this might be right for
Philadelphia Chromosome Negative ALLAcute Lymphoblastic Leukemia, Adult
Institute of Hematology & Blood Diseases Hospital, China 77
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