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Results for “Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia”

82 trials

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Showing 20 of 82 results

Testing effectiveness (Phase 2)Study completedNCT02458014
What this trial is testing

Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Disease

Who this might be right for
Adult Acute Lymphoblastic Leukemia in Complete RemissionB Acute Lymphoblastic LeukemiaMinimal Residual Disease+1 more
M.D. Anderson Cancer Center 36
Testing effectiveness (Phase 2)Study completedNCT01279473
What this trial is testing

Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study)

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia
Novartis Pharmaceuticals 42
Testing effectiveness (Phase 2)Study completedNCT00109707
What this trial is testing

Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)Hypereosinophilic Syndrome+1 more
Novartis Pharmaceuticals 507
Large-scale testing (Phase 3)UnknownNCT02611492
What this trial is testing

A Phase III Randomized Trial of the Reduction of Chemotherapy in Philadelphia Chromosome-positive ALL of Young Adults

Who this might be right for
Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia
Assistance Publique - Hôpitaux de Paris 265
Testing effectiveness (Phase 2)Study completedNCT02067143
What this trial is testing

MRD/Risk-oriented Therapy of Adult Ph- ALL Including Pegylated Asparaginase and Lineage-targeted Methotrexate

Who this might be right for
Untreated Philadelphia Positive Acute Lymphoblastic LeukemiaDe NovoSecondary+1 more
Gruppo Italiano Malattie EMatologiche dell'Adulto 204
Testing effectiveness (Phase 2)WithdrawnNCT01670084
What this trial is testing

Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia

Who this might be right for
B-cell Adult Acute Lymphoblastic LeukemiaBlastic Phase Chronic Myelogenous LeukemiaChronic Myelogenous Leukemia, BCR-ABL1 Positive+2 more
Mayo Clinic
Testing effectiveness (Phase 2)UnknownNCT05466175
What this trial is testing

Olverembatinib in the Treatment of Ph+ ALL

Who this might be right for
Philadelphia-Positive ALL
Chen Suning 55
Testing effectiveness (Phase 2)Study completedNCT00787761
What this trial is testing

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Who this might be right for
Myeloproliferative DisordersKidney CancerLeukemia+4 more
Northside Hospital, Inc. 24
Testing effectiveness (Phase 2)Study completedNCT00702403
What this trial is testing

Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CML

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionBlastic Phase Chronic Myelogenous Leukemia+11 more
Fred Hutchinson Cancer Center 40
Large-scale testing (Phase 3)UnknownNCT04375683
What this trial is testing

Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL

Who this might be right for
Acute Lymphocytic Leukemia, Adult B-CellBCR-ABL1 Fusion Protein Expression
Zhongda Hospital 28
Early research (Phase 1)Study completedNCT01925131
What this trial is testing

S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineageB-cell Adult Acute Lymphoblastic LeukemiaPhiladelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia+2 more
SWOG Cancer Research Network 50
Testing effectiveness (Phase 2)Temporarily pausedNCT03739814
What this trial is testing

Inotuzumab Ozogamicin and Blinatumomab in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeRecurrent B Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT01424982
What this trial is testing

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAdult Acute Lymphoblastic Leukemia in Complete Remission+4 more
M.D. Anderson Cancer Center 88
Not applicableEnded earlyNCT00608517
What this trial is testing

Treatment of Single or Double Umbilical Cord Trans + Graft-versus-host Disease (GVHD) Prophylaxis w/ Tacrolimus & Mycophenolate Mofetil

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+2 more
Vanderbilt-Ingram Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT00376467
What this trial is testing

STI 571 (GLIVEC) in the Treatment of Adult Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 105
Testing effectiveness (Phase 2)Ended earlyNCT03523429
What this trial is testing

PETHEMA-BLIN-01/PET069014 (BLIN-01)

Who this might be right for
Philadelphia Chromosome-negative or BCR-ABL-negative, CD19-positive ALL
PETHEMA Foundation 11
Testing effectiveness (Phase 2)Ended earlyNCT04554459
What this trial is testing

Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL

Who this might be right for
Acute Lymphoblastic Leukemia, AdultPh+ ALLNewly Diagnosed
Institute of Hematology and Blood Transfusion, Czech Republic 4
Testing effectiveness (Phase 2)WithdrawnNCT04845035
What this trial is testing

Pediatric-Inspired Chemotherapy Plus Tyrosine Kinase Inhibitor in Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
University of Michigan Rogel Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT00723203
What this trial is testing

Panobinostat in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Who this might be right for
Leukemia
City of Hope Medical Center 16
Large-scale testing (Phase 3)Active Not RecruitingNCT04722848
What this trial is testing

Sequential Treatment With Ponatinib and Blinatumomab vs Chemotherapy and Imatinib in Newly Diagnosed Adult Ph+ ALL

Who this might be right for
Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)ALL, AdultPhiladelphia-Positive ALL
Gruppo Italiano Malattie EMatologiche dell'Adulto 236
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