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Results for “Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia”

25 trials

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Showing 20 of 25 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04475731
What this trial is testing

Ponatinib in Adult Ph+ ALL Patients With MRD Positivity or Hematological Relapse

Who this might be right for
Philadelphia-Positive ALLAcute Lymphoblastic Leukemia, in Relapse
Gruppo Italiano Malattie EMatologiche dell'Adulto 67
Early research (Phase 1)Study completedNCT00316953
What this trial is testing

Dasatinib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaBlastic Phase Chronic Myelogenous LeukemiaChildhood Chronic Myelogenous Leukemia+5 more
National Cancer Institute (NCI) 48
Early research (Phase 1)Study completedNCT00005092
What this trial is testing

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
M.D. Anderson Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT01427881
What this trial is testing

Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Megakaryoblastic Leukemia (M7)+65 more
Fred Hutchinson Cancer Center 43
Testing effectiveness (Phase 2)Looking for participantsNCT06220487
What this trial is testing

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL

Who this might be right for
Acute Lymphoblastic LeukemiaPhiladelphia ChromosomePhiladelphia-Positive ALL+2 more
Nanfang Hospital, Southern Medical University 67
Large-scale testing (Phase 3)Study completedNCT00720109
What this trial is testing

Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
National Cancer Institute (NCI) 63
Large-scale testing (Phase 3)Study completedNCT00265837
What this trial is testing

Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+3 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 72
Testing effectiveness (Phase 2)UnknownNCT00008307
What this trial is testing

Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
Herbert Irving Comprehensive Cancer Center 52
Early research (Phase 1)Looking for participantsNCT06287528
What this trial is testing

19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia-Negative ALLPhiladelphia-Positive ALLRelapsed ALL, Adult+3 more
Memorial Sloan Kettering Cancer Center 18
Testing effectiveness (Phase 2)Study completedNCT00061945
What this trial is testing

Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia

Who this might be right for
Acute Undifferentiated LeukemiaB-cell Adult Acute Lymphoblastic LeukemiaB-cell Childhood Acute Lymphoblastic Leukemia+11 more
National Cancer Institute (NCI) 302
Testing effectiveness (Phase 2)UnknownNCT05466175
What this trial is testing

Olverembatinib in the Treatment of Ph+ ALL

Who this might be right for
Philadelphia-Positive ALL
Chen Suning 55
Early research (Phase 1)UnknownNCT05495035
What this trial is testing

Study for Safety and Efficacy of Olverembatinib Combined With APG-2575 in Children With Relapsed/Refractory Ph + ALL

Who this might be right for
Lymphoblastic Leukemia, Acute, ChildhoodLeukemia, Lymphoblastic, Acute, Philadelphia-PositiveRelapsed Leukemia+1 more
Institute of Hematology & Blood Diseases Hospital, China 22
Large-scale testing (Phase 3)Looking for participantsNCT07152041
What this trial is testing

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)Childhood Leukemia, Acute Lymphoblastic
Institute of Hematology & Blood Diseases Hospital, China 150
Testing effectiveness (Phase 2)Study completedNCT01445080
What this trial is testing

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Who this might be right for
Blastic PhaseChildhood Acute Promyelocytic Leukemia With PML-RARAChildhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive+7 more
National Cancer Institute (NCI) 70
Large-scale testing (Phase 3)Active Not RecruitingNCT04722848
What this trial is testing

Sequential Treatment With Ponatinib and Blinatumomab vs Chemotherapy and Imatinib in Newly Diagnosed Adult Ph+ ALL

Who this might be right for
Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)ALL, AdultPhiladelphia-Positive ALL
Gruppo Italiano Malattie EMatologiche dell'Adulto 236
Testing effectiveness (Phase 2)Study completedNCT00702403
What this trial is testing

Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CML

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionBlastic Phase Chronic Myelogenous Leukemia+11 more
Fred Hutchinson Cancer Center 40
Not applicableStudy completedNCT00003538
What this trial is testing

Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation

Who this might be right for
Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Not applicableEnded earlyNCT00008216
What this trial is testing

Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Adult Langerhans Cell HistiocytosisChildhood Langerhans Cell HistiocytosisLeukemia+4 more
Columbia University 48
Early research (Phase 1)Ended earlyNCT02819804
What this trial is testing

Nivolumab and Dasatinib in Treating Patients With Relapsed or Refractory Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Lymphoblastic Leukemia+2 more
Northwestern University 1
Large-scale testing (Phase 3)Study completedNCT01190930
What this trial is testing

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Who this might be right for
Acute Lymphoblastic LeukemiaAdult B Lymphoblastic LymphomaAnn Arbor Stage I B Lymphoblastic Lymphoma+7 more
Children's Oncology Group 9,350
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