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Results for “Philadelphia Chromosome-negative CML”

134 trials

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Showing 20 of 134 results

Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Testing effectiveness (Phase 2)Study completedNCT01279473
What this trial is testing

Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study)

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia
Novartis Pharmaceuticals 42
Large-scale testing (Phase 3)UnknownNCT00002869
What this trial is testing

Interferon Alfa in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
Medical Research Council 800
Early research (Phase 1)Study completedNCT01374139
What this trial is testing

Bioequivalence And Food Effect Study Of Bosutinib In Healthy Subjects

Who this might be right for
Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia (CML)
Pfizer 88
Testing effectiveness (Phase 2)Study completedNCT00109707
What this trial is testing

Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)Hypereosinophilic Syndrome+1 more
Novartis Pharmaceuticals 507
Testing effectiveness (Phase 2)Study completedNCT01274351
What this trial is testing

Study of Nilotinib as First Line Treatment in Philadelphia Chromosome Positive(Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)

Who this might be right for
Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 112
Testing effectiveness (Phase 2)WithdrawnNCT00446173
What this trial is testing

Autologous Stem Cell Transplants for Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT00006052
What this trial is testing

STI571 in Treating Patients With Accelerated Phase Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
Novartis
Testing effectiveness (Phase 2)Study completedNCT01844765
What this trial is testing

Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.

Who this might be right for
Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 59
Testing effectiveness (Phase 2)Study completedNCT00787761
What this trial is testing

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Who this might be right for
Myeloproliferative DisordersKidney CancerLeukemia+4 more
Northside Hospital, Inc. 24
Large-scale testing (Phase 3)Study completedNCT02326311
What this trial is testing

Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients ≥60 Years in Deep Molecular Response

Who this might be right for
Leukemia, Chronic Myeloid
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 229
Post-approval studies (Phase 4)Ended earlyNCT01131325
What this trial is testing

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations

Who this might be right for
CMLPhiladelphia Chromosome Positive (Ph+)Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels
Novartis Pharmaceuticals 3
Not applicableStudy completedNCT03678454
What this trial is testing

Iclusig® (Ponatinib) in Clinical Practice for the Treatment of Chronic Myeloid Leukemia or Ph+ Acute Lymphoblastic Leukemia in Belgium

Who this might be right for
Chronic Myeloid LeukemiaCMLPhiladelphia Chromosome-positive Acute Lymphoblastic Leukemia+1 more
Incyte Biosciences Benelux 80
Large-scale testing (Phase 3)UnknownNCT00025402
What this trial is testing

Chemotherapy and Biological Therapy With or Without Bone Marrow or Peripheral Stem Cell Transplant in Treating Patients With Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
III. Medizinische Klinik Mannheim 1,000
Not applicableStudy completedNCT03509896
What this trial is testing

Study of Chinese Newly Diagnosed Participants With Philadelphia Chromosome-Positive (Ph+) Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

Who this might be right for
Chronic Myeloid LeukemiaPhiladelphia ChromosomeChronic Myeloid Leukemia in Chronic Phase
Bristol-Myers Squibb 463
Large-scale testing (Phase 3)Looking for participantsNCT03459534
What this trial is testing

The Efficacy and Safety of Radotinib in CP-CML Patients With Failure or Intolerance to Previous TKIs

Who this might be right for
Chronic Myeloid Leukemia, Chronic PhaseCML, Chronic PhaseCML, Refractory+1 more
Il-Yang Pharm. Co., Ltd. 173
Testing effectiveness (Phase 2)Study completedNCT01698905
What this trial is testing

Treatment-free Remission After Achieving Sustained MR4.5 on Nilotinib (ENESTop)

Who this might be right for
Chronic Myeloid Leukemia
Novartis Pharmaceuticals 163
Post-approval studies (Phase 4)Active Not RecruitingNCT06427811
What this trial is testing

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation

Who this might be right for
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
Novartis Pharmaceuticals 85
Not applicableUnknownNCT01562847
What this trial is testing

Prospective Investigation of Dynamics of ABL Mutations in Imatinib Failed CML Patients Treated With Nilotinib

Who this might be right for
Chronic Myeloid Leukemia
Seoul St. Mary's Hospital 125
Testing effectiveness (Phase 2)Study completedNCT00769327
What this trial is testing

Nilotinib and Imatinib Mesylate in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 129
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