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Results for “Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia”

174 trials

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Showing 20 of 174 results

Testing effectiveness (Phase 2)Study completedNCT00982488
What this trial is testing

Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Bristol-Myers Squibb 238
Testing effectiveness (Phase 2)Active Not RecruitingNCT03512405
What this trial is testing

Pembrolizumab and Blinatumomab in Treating Participants With Recurrent or Refractory Acute Lymphoblastic Leukemia

Who this might be right for
CD19 PositivePhiladelphia Chromosome PositiveRecurrent Acute Lymphoblastic Leukemia+1 more
City of Hope Medical Center 36
Early research (Phase 1)Study completedNCT00352677
What this trial is testing

Safety and Tolerability Study of INNO-406 to Treat Chronic Myeloid Leukemia or Acute Lymphocytic Leukemia

Who this might be right for
Chronic Myeloid LeukemiaAcute Lymphocytic Leukemia
CytRx 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT02143414
What this trial is testing

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1+2 more
National Cancer Institute (NCI) 53
Early research (Phase 1)Ended earlyNCT00500006
What this trial is testing

A Phase I Dose Escalation Combination Study in Patients With Chronic Myelogenous Leukemia (CML) and Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)(0457-009)(TERMINATED)

Who this might be right for
Chronic Myelogenous LeukemiaLeukemia, Lymphoblastic, Acute, Philadelphia-Positive
Merck Sharp & Dohme LLC 3
Testing effectiveness (Phase 2)Ended earlyNCT03576547
What this trial is testing

Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia

Who this might be right for
Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositivePhiladelphia Chromosome PositiveRecurrent Acute Lymphoblastic Leukemia+4 more
M.D. Anderson Cancer Center 9
Testing effectiveness (Phase 2)Ended earlyNCT02629692
What this trial is testing

Safety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML Therapies

Who this might be right for
Healthy (For Part A)Chronic Myeloid Leukemia (for Part B and C)
Sun Pharma Advanced Research Company Limited 124
Large-scale testing (Phase 3)Active Not RecruitingNCT03007147
What this trial is testing

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia+1 more
Children's Oncology Group 475
Testing effectiveness (Phase 2)UnknownNCT02776605
What this trial is testing

Ponatinib With Chemotherapy for Young Adults Ph Positive Acute Lymphoblastic Leukemia

Who this might be right for
ALL
PETHEMA Foundation 30
Testing effectiveness (Phase 2)Study completedNCT00618501
What this trial is testing

Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Asan Medical Center 50
Early research (Phase 1)Ended earlyNCT01066468
What this trial is testing

Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders.

Who this might be right for
Chronic Myeloid Leukemia (CML)Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)Other Glivec/Gleevec Indicated Hematological Disorders (HES, CEL, MDS/ MPN)
Novartis Pharmaceuticals 3
Testing effectiveness (Phase 2)Study completedNCT02458014
What this trial is testing

Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Disease

Who this might be right for
Adult Acute Lymphoblastic Leukemia in Complete RemissionB Acute Lymphoblastic LeukemiaMinimal Residual Disease+1 more
M.D. Anderson Cancer Center 36
Early research (Phase 1)Study completedNCT00316953
What this trial is testing

Dasatinib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaBlastic Phase Chronic Myelogenous LeukemiaChildhood Chronic Myelogenous Leukemia+5 more
National Cancer Institute (NCI) 48
Testing effectiveness (Phase 2)UnknownNCT00199186
What this trial is testing

Study Comparing Imatinib With Chemotherapy as Induction in Elderly Patients With Philadelphia Positive Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia Positive Acute Lymphoblastic LeukemiaLymphoid Blastic Phase of Chronic Myeloid Leukemia
Johann Wolfgang Goethe University Hospital
Not applicableEnded earlyNCT01148134
What this trial is testing

Pharmacokinetic Profile of Vincristine Administered With Imatinib for Bcr-Abl Positive Acute Lymphoblastic Leukemia (ALL) Compared to That Without Imatinib for Bcr-Abl Negative ALL

Who this might be right for
Acute Lymphoblastic Leukemia
University Health Network, Toronto 10
Not applicableStudy completedNCT07644351
What this trial is testing

A Real-world Study of Asciminib Effectiveness in Philadelphia Positive Acute Lymphoblastic Leukemia Patients

Who this might be right for
Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals 37
Large-scale testing (Phase 3)UnknownNCT03624530
What this trial is testing

Effect of Prophylactic TKI Therapy Post-transplants on Ph+ ALL Undergoing Allo-HSCT With MRD Positive Pre-transplants

Who this might be right for
Philadelphia Chromosome Positive Acute Lymphocytic LeukemiaTyrosine Kinase InhibitorMinimal Residual Disease+1 more
Nanfang Hospital, Southern Medical University 82
Testing effectiveness (Phase 2)Ended earlyNCT04554459
What this trial is testing

Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL

Who this might be right for
Acute Lymphoblastic Leukemia, AdultPh+ ALLNewly Diagnosed
Institute of Hematology and Blood Transfusion, Czech Republic 4
Early research (Phase 1)Study completedNCT00940524
What this trial is testing

Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Who this might be right for
LeukemiaAcute Lymphoblastic Leukemia
Memorial Sloan Kettering Cancer Center 7
Not applicableStudy completedNCT00068523
What this trial is testing

Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+3 more
Case Comprehensive Cancer Center 10
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