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Results for “Philadelphia Chromosome-positive B-cell Acute Lymphoblastic Leukemia (Ph+ B-ALL)”

46 trials

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Showing 20 of 46 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02143414
What this trial is testing

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1+2 more
National Cancer Institute (NCI) 53
Large-scale testing (Phase 3)Active Not RecruitingNCT03007147
What this trial is testing

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia+1 more
Children's Oncology Group 475
Testing effectiveness (Phase 2)Study completedNCT02458014
What this trial is testing

Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Disease

Who this might be right for
Adult Acute Lymphoblastic Leukemia in Complete RemissionB Acute Lymphoblastic LeukemiaMinimal Residual Disease+1 more
M.D. Anderson Cancer Center 36
Not applicableStudy completedNCT00068523
What this trial is testing

Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+3 more
Case Comprehensive Cancer Center 10
Early research (Phase 1)Study completedNCT00005092
What this trial is testing

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
M.D. Anderson Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT01427881
What this trial is testing

Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Megakaryoblastic Leukemia (M7)+65 more
Fred Hutchinson Cancer Center 43
Early research (Phase 1)Study completedNCT00114257
What this trial is testing

Decitabine and FR901228 in Treating Patients With Relapsed or Refractory Leukemia, Myelodysplastic Syndromes, or Myeloproliferative Disorders

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaMyelodysplastic Syndromes+1 more
National Cancer Institute (NCI) 36
Large-scale testing (Phase 3)Study completedNCT00720109
What this trial is testing

Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
National Cancer Institute (NCI) 63
Testing effectiveness (Phase 2)Study completedNCT02228096
What this trial is testing

Study of Efficacy and Safety of CTL019 in Pediatric ALL Patients

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaRelapsed B-cell Acute Lymphoblastic LeukemiaRefractory B-cell Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals 75
Testing effectiveness (Phase 2)Active Not RecruitingNCT01424982
What this trial is testing

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAdult Acute Lymphoblastic Leukemia in Complete Remission+4 more
M.D. Anderson Cancer Center 88
Large-scale testing (Phase 3)UnknownNCT04375683
What this trial is testing

Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL

Who this might be right for
Acute Lymphocytic Leukemia, Adult B-CellBCR-ABL1 Fusion Protein Expression
Zhongda Hospital 28
Large-scale testing (Phase 3)Study completedNCT00265837
What this trial is testing

Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+3 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 72
Testing effectiveness (Phase 2)Study completedNCT01769209
What this trial is testing

Bortezomib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Adult Acute Lymphoblastic Leukemia (ALL)Ph-positive Adult Acute Lymphoblastic Leukemia (ALL)Recurrent Adult Acute Lymphoblastic Leukemia (ALL)+1 more
Stanford University 18
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07493408
What this trial is testing

Asciminib & Standard-of-Care Integration in Maintenance Therapy for POST Allogeneic Stem Cell Transplant (Allo-HSCT) of Patient With Ph+ B-ALL or Blastic Transformed CML

Who this might be right for
Ph+ Acute Lymphoblastic Leukemia (Ph+ALL)Blastic Transformation of Chronic Myeloid LeukemiaPhiladelphia Chromosome-positive B-cell Acute Lymphoblastic Leukemia (Ph+ B-ALL)+1 more
The University of Hong Kong
Testing effectiveness (Phase 2)Looking for participantsNCT06754267
What this trial is testing

Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALL

Who this might be right for
Precursor B-Cell Acute Lymphoblastic Leukemia
First Affiliated Hospital of Zhejiang University 36
Testing effectiveness (Phase 2)Looking for participantsNCT03739814
What this trial is testing

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeRecurrent B Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 84
Early research (Phase 1)Not Yet RecruitingNCT07040982
What this trial is testing

Asciminib as Maintenance Treatment After Cellular Therapies for Adults With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
City of Hope Medical Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06124157
What this trial is testing

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Who this might be right for
B Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 222
Testing effectiveness (Phase 2)UnknownNCT00008307
What this trial is testing

Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
Herbert Irving Comprehensive Cancer Center 52
Early research (Phase 1)Looking for participantsNCT06287528
What this trial is testing

19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia-Negative ALLPhiladelphia-Positive ALLRelapsed ALL, Adult+3 more
Memorial Sloan Kettering Cancer Center 18
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