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Results for “Philadelphia Positive”

318 trials

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Showing 20 of 318 results

Testing effectiveness (Phase 2)Study completedNCT00002674
What this trial is testing

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
Fred Hutchinson Cancer Center 30
Testing effectiveness (Phase 2)Study completedNCT01279473
What this trial is testing

Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study)

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia
Novartis Pharmaceuticals 42
Testing effectiveness (Phase 2)Study completedNCT01310010
What this trial is testing

Study of Dasatinib to Treat Philadelphia Positive Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
Grupo Espanol de trasplantes hematopoyeticos y terapia celular 30
Testing effectiveness (Phase 2)Study completedNCT00381550
What this trial is testing

3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAtypical Chronic Myeloid Leukemia, BCR-ABL1 NegativeBlastic Phase Chronic Myelogenous Leukemia+7 more
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07301424
What this trial is testing

Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL+ B-ALL

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)BCR-ABL Positive Acute Lymphoblastic Leukemia
University of Alberta 80
Testing effectiveness (Phase 2)Study completedNCT00038597
What this trial is testing

Phase II Study of SCH66336, A Farnesyltransferase Inhibitor in Chronic Myelogenous Leukemia (CML)

Who this might be right for
Myelogenous Leukemia, Chronic
M.D. Anderson Cancer Center 13
Early research (Phase 1)Looking for participantsNCT03595917
What this trial is testing

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaChronic Myeloid Leukemia (CML) in Lymphoid Blast CrisisPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia Ph+ ALL
Marlise Luskin, MD 40
Not applicableStudy completedNCT01699217
What this trial is testing

Front-line Nilotinib Treatment of BCR-ABL+ Chronic Myeloid Leukaemia in Chronic Phase

Who this might be right for
Chronic Phase Philadelphia PositiveBCR-ABL PositiveChronic Myeloid Leukaemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 129
Early research (Phase 1)Active Not RecruitingNCT04872790
What this trial is testing

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Mixed Phenotype Acute Leukemia+2 more
OHSU Knight Cancer Institute 20
Early research (Phase 1)Ended earlyNCT03519984
What this trial is testing

EphB4-HSA Fusion Protein and Cytarabine /or Liposomal Vincristine in Patients With Recurrent or Refractory Acute Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlasts 5 Percent or More of Bone Marrow Nucleated CellsMyelodysplastic/Myeloproliferative Neoplasm+8 more
University of Southern California 3
Testing effectiveness (Phase 2)Ended earlyNCT00038649
What this trial is testing

Therapy of Early Chronic Phase CML With Higher-Dose Gleevec, Alpha Interferon, and Low-Dose Ara-C

Who this might be right for
Myelogenous Leukemia, Chronic, Chronic Phase
M.D. Anderson Cancer Center 117
Testing effectiveness (Phase 2)Study completedNCT00769327
What this trial is testing

Nilotinib and Imatinib Mesylate in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 129
Post-approval studies (Phase 4)Ended earlyNCT05071482
What this trial is testing

Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALL

Who this might be right for
Acute Leukemia
Institute of Hematology & Blood Diseases Hospital, China 39
Testing effectiveness (Phase 2)WithdrawnNCT00446173
What this trial is testing

Autologous Stem Cell Transplants for Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT03625388
What this trial is testing

Low Dose Dasatinib (50 mg Daily) as First-line Treatment for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia

Who this might be right for
Chronic Myelogenous Leukemia
Hikma Pharmaceuticals LLC 56
Early research (Phase 1)Ended earlyNCT00907517
What this trial is testing

Study of SCH 900776 (MK-8776) With and Without Cytarabine in Participants With Acute Leukemias (P05247)

Who this might be right for
Myelogenous Leukemia, AcuteLeukemia, Lymphocytic, AcuteLeukemia, Lymphoblastic, Acute, Philadelphia-Positive+1 more
Merck Sharp & Dohme LLC 24
Early research (Phase 1)Study completedNCT01456676
What this trial is testing

Nilotinib and LDE225 in the Treatment of Chronic or Accelerated Phase Myeloid Leukemia in Patients Who Developed Resistance to Prior Therapy

Who this might be right for
Philadelphia Chromosome Positive Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 11
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Not applicableStudy completedNCT00003538
What this trial is testing

Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation

Who this might be right for
Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Large-scale testing (Phase 3)Ended earlyNCT00519090
What this trial is testing

Nilotinib vs Imatinib in Adult Patients With Philadelphia (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)

Who this might be right for
Myelogenous Leukemia
Novartis Pharmaceuticals 6
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