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Results for “Phosphodiesterase Inhibitor”

91 trials

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Showing 20 of 91 results

Testing effectiveness (Phase 2)Study completedNCT04854811
What this trial is testing

Roflumilast to Treat Cognitive Sequela After Stroke

Who this might be right for
Cerebrovascular DisordersMemoryFunctional Recovery+1 more
Maastricht University 100
Testing effectiveness (Phase 2)Study completedNCT04161456
What this trial is testing

Preliminary Efficacy and Safety of Apremilast in the Treatment of Acne Conglobata

Who this might be right for
Acne Conglobata
Dr. Frank Behrens 1
Early research (Phase 1)Study completedNCT01602900
What this trial is testing

Healthy Volunteer Positron Emission Tomography (PET) Brain Occupancy Study of a Phosphodiesterase 4 (PDE4) Inhibitor in Huntington's Disease

Who this might be right for
Huntington Disease
GlaxoSmithKline 8
Early research (Phase 1)Study completedNCT02208934
What this trial is testing

Study To Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-999 in Healthy Young Male Volunteers

Who this might be right for
Huntington's Disease
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 32
Post-approval studies (Phase 4)Ended earlyNCT01275339
What this trial is testing

Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Study

Who this might be right for
Aortic StenosisLV Remodeling, Hypertrophy
Washington University School of Medicine 10
Testing effectiveness (Phase 2)Study completedNCT01090492
What this trial is testing

PF-00489791 For The Treatment Of Raynaud's

Who this might be right for
Raynaud's DiseasePeripheral Vascular Disease
Pfizer 243
Testing effectiveness (Phase 2)Study completedNCT01856764
What this trial is testing

Topical Roflumilast in Adults With Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
AstraZeneca 40
Large-scale testing (Phase 3)Study completedNCT00242307
What this trial is testing

Efficacy and Safety of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 70 y) (APTA-2217-05)

Who this might be right for
Bronchial Asthma
AstraZeneca 450
Testing effectiveness (Phase 2)Study completedNCT01132482
What this trial is testing

Effects of Sildenafil on CFTR-dependent Ion Transport Activity

Who this might be right for
Cystic Fibrosis
National Jewish Health 19
Early research (Phase 1)Ended earlyNCT02907294
What this trial is testing

Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 "After Multiple Oral Doses" in Healthy Volunteers

Who this might be right for
Huntington Disease
Palobiofarma SL 8
Early research (Phase 1)Study completedNCT02001389
What this trial is testing

Study of EVP-6308 to Assess the Dose- and Concentration-dependent Displacement of [18F]MNI-659 by EVP-6308

Who this might be right for
Healthy
FORUM Pharmaceuticals Inc 14
Large-scale testing (Phase 3)Study completedNCT00242294
What this trial is testing

Efficacy and Safety of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-06)

Who this might be right for
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca 570
Not applicableUnknownNCT02845765
What this trial is testing

Fundus Oculi and Erectile Dysfunction

Who this might be right for
Erectile Dysfunction
Ospedale San Raffaele 60
Testing effectiveness (Phase 2)Study completedNCT00659529
What this trial is testing

Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung Disease

Who this might be right for
Cystic Fibrosis
National Jewish Health 36
Early research (Phase 1)Not Yet RecruitingNCT06724042
What this trial is testing

Study of ISM5939 in Patients With Advanced and/or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorAdvanced and/or Metastatic Solid Tumors
InSilico Medicine Hong Kong Limited 159
Not applicableWithdrawnNCT05458232
What this trial is testing

Use of a Phosphodiesterase Type 5 Inhibitor to Improve Anabolic Resistance in Older Adults

Who this might be right for
Sarcopenia
University of Arkansas
Post-approval studies (Phase 4)WithdrawnNCT00817830
What this trial is testing

Cardiovascular Safety Study of Lodenafil Carbonate in Patients With Coronaropathy During Physical Effort

Who this might be right for
Erectile DysfunctionCoronaropathy
Cristália Produtos Químicos Farmacêuticos Ltda.
Early research (Phase 1)Study completedNCT02363335
What this trial is testing

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

Who this might be right for
Healthy Volunteers
National Institute on Aging (NIA) 29
Post-approval studies (Phase 4)Study completedNCT00303459
What this trial is testing

Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 334
Post-approval studies (Phase 4)Study completedNCT00862043
What this trial is testing

Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease

Who this might be right for
Pulmonary HypertensionValvular Heart Disease
Hospital General Universitario Gregorio Marañon 200
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