Not applicableStudy completedNCT00685945What this trial is testingRenin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3Who this might be right forObesity Vanderbilt University 24
Early research (Phase 1)Study completedNCT00250172What this trial is testingPET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]RolipramWho this might be right forDosimetryHealthy National Institute of Mental Health (NIMH) 26
Testing effectiveness (Phase 2)Study completedNCT00940901What this trial is testingSildenafil for Treatment of Priapism in Men With Sickle Cell AnemiaWho this might be right forSickle Cell DiseasePriapism Johns Hopkins University 13
Not applicableStudy completedNCT00909233What this trial is testingLEVITRA® 20mg Special Drug Use Investigation (Long-term)Who this might be right forErectile Dysfunction Bayer 1,221
Post-approval studies (Phase 4)Ended earlyNCT01272388What this trial is testingAortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot StudyWho this might be right forAortic Stenosis Washington University School of Medicine 1
Testing effectiveness (Phase 2)Study completedNCT01168817What this trial is testingClinical Proof-of-concept Study for the Combination BAY60-4552 / Vardenafil for the Treatment of Erectile Dysfunction Not Sufficiently Responsive to Standard Therapy With PDE5 InhibitorsWho this might be right forErectile Dysfunction Bayer 140
Testing effectiveness (Phase 2)Study completedNCT01393158What this trial is testingApremilast for Atopic Dermatitis - A Pilot Study in AdultsWho this might be right forAtopic Dermatitis Oregon Health and Science University 16
Testing effectiveness (Phase 2)WithdrawnNCT05030623What this trial is testingThe Phosphodiesterase Inhibitor Tadalafil as an Adjunct to Antidepressants in Major Depressive Disorder PatientsWho this might be right forMajor Depressive Disorder Sadat City University
Large-scale testing (Phase 3)Temporarily pausedNCT04052269What this trial is testingPhosphodiesterase Inhibitors in Glaucoma Study (PhiGS)Who this might be right forGlaucoma Imperial College London 30
Not applicableUnknownNCT01566006What this trial is testingMycophenolate Mofetil, Carnitine and PDE5 Inhibitor, Three Potential Treatments for Resistant Proteinuria Slowing Diabetic Nephropathy DeteriorationWho this might be right forDiabetic NephropathyChronic Kidney Disease The Nazareth Hospital, Israel 80
Post-approval studies (Phase 4)Ended earlyNCT01275339What this trial is testingAortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot StudyWho this might be right forAortic StenosisLV Remodeling, Hypertrophy Washington University School of Medicine 10
Not applicableUnknownNCT02835716What this trial is testingPre-Clinical (Alzheimers) Diagnosis PCD = Optimum Outcomes OOWho this might be right forAlzheimer Disease Millennium Magnetic Technologies, LLC 150
Testing effectiveness (Phase 2)UnknownNCT06118047What this trial is testingCrisaborole Ointment for Skin Toxicity Induced by CetuximabWho this might be right forMetastatic Colorectal CancerCetuximabSkin Toxicity Sun Yat-sen University 33
Post-approval studies (Phase 4)Study completedNCT01130532What this trial is testingA Study in Erectile DysfunctionWho this might be right forErectile Dysfunction Eli Lilly and Company 623
Not applicableStudy completedNCT01207947What this trial is testingLEVITRA® Specific Drug Use Investigation. To Investigate the Safety Profile in Combination Use With Alpha-blockersWho this might be right forErectile Dysfunction Bayer 491
Early research (Phase 1)Study completedNCT01918202What this trial is testingEvaluate The PDE10 Enzyme Occupancy Following A Single Dose Of PF-02545920 In Healthy Male VolunteersWho this might be right forHealthy Pfizer 9
Very early researchLooking for participantsNCT06643221What this trial is testingExercise as an Immune Adjuvant for Allogeneic Cell TherapiesWho this might be right forLeukemiaHematopoetic Stem Cell TransplantationDonor Lymphocyte Infusion+3 more University of Arizona 200
Testing effectiveness (Phase 2)UnknownNCT03656666What this trial is testingThe AP-GELP Study: A Clinical Trial on the Effects of Apremilast in Female Genital Erosive Lichen PlanusWho this might be right forLichen Planus of VulvaFemale Genital Disease Oslo University Hospital 42
Early research (Phase 1)Ended earlyNCT04108377What this trial is testingPhosphodiesterase 4 Inhibitor, Roflumilast, and the Effects of Inhibition in Severe AsthmaWho this might be right forAsthma University of California, Davis 5
Large-scale testing (Phase 3)Study completedNCT00549302What this trial is testingStudy the Safety and Effectiveness of Tadalafil on High Blood Pressure in the Blood Vessel Going From the Heart to the LungsWho this might be right forHypertension, Pulmonary Eli Lilly and Company 357