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Results for “Platinum-Resistant Lung Small Cell Carcinoma”

42 trials

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Showing 20 of 42 results

Early research (Phase 1)Study completedNCT06517433
What this trial is testing

First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b

Who this might be right for
Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic
Mersana Therapeutics 62
Early research (Phase 1)Ended earlyNCT06264921
What this trial is testing

A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorSolid Tumor, AdultAdvanced Solid Tumor+26 more
NiKang Therapeutics, Inc. 23
Early research (Phase 1)Looking for participantsNCT05353439
What this trial is testing

Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaLimited Stage Lung Small Cell CarcinomaPlatinum-Resistant Lung Small Cell Carcinoma+3 more
National Cancer Institute (NCI) 60
Testing effectiveness (Phase 2)Study completedNCT02797964
What this trial is testing

A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
Sierra Oncology LLC - a GSK company 107
Large-scale testing (Phase 3)Looking for participantsNCT07217301
What this trial is testing

IBI363 vs Docetaxel in Patients With Advanced Squamous Lung Cancer After Standard Treatments Have Failed

Who this might be right for
iO Resistant sqNSCLC
Fortvita Biologics (USA)Inc. 600
Testing effectiveness (Phase 2)Ended earlyNCT02554812
What this trial is testing

Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)

Who this might be right for
Advanced Cancer
Pfizer 409
Testing effectiveness (Phase 2)Looking for participantsNCT05914116
What this trial is testing

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors
DualityBio Inc. 862
Testing effectiveness (Phase 2)Study completedNCT00116610
What this trial is testing

Picoplatin as Second-Line Therapy for Patients With Small Cell Lung Cancer

Who this might be right for
Small Cell Lung Cancer
Poniard Pharmaceuticals 75
Testing effectiveness (Phase 2)Looking for participantsNCT05081609
What this trial is testing

Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+10 more
Ascendis Pharma Oncology Division A/S 345
Testing effectiveness (Phase 2)Ended earlyNCT04971187
What this trial is testing

Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer

Who this might be right for
Locally Advanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+7 more
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944772
What this trial is testing

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 247
Testing effectiveness (Phase 2)Active Not RecruitingNCT03319628
What this trial is testing

First-in-Human Study of XMT-1536 in Cancers Likely to Express NaPi2b

Who this might be right for
Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic
Mersana Therapeutics 523
Early research (Phase 1)Ended earlyNCT02468661
What this trial is testing

A Safety and Efficacy Study of INC280 Alone, and in Combination With Erlotinib, Compared to Chemotherapy, in Advanced/Metastatic Non-small Cell Lung Cancer Patients With EGFR Mutation and cMET Amplification

Who this might be right for
Non-Small Cell Lung Cancer
Novartis Pharmaceuticals 23
Testing effectiveness (Phase 2)Looking for participantsNCT05985655
What this trial is testing

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)Pancreatic AdenocarcinomaNon-small Cell Lung Cancer (NSCLC)+3 more
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc. 230
Testing effectiveness (Phase 2)Active Not RecruitingNCT04607954
What this trial is testing

Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung Cancer

Who this might be right for
Platinum-Resistant Lung Small Cell CarcinomaPlatinum-Sensitive Lung Small Cell CarcinomaRecurrent Extensive Stage Lung Small Cell Carcinoma+1 more
Mayo Clinic 29
Testing effectiveness (Phase 2)Study completedNCT00284141
What this trial is testing

Study of AVE0005 (VEGF Trap) in Locally Advanced or Metastatic Platinum- and Erlotinib- Resistant Non-small-cell-lung Adenocarcinoma

Who this might be right for
Pulmonary DiseasesNeoplasms, Lung
Sanofi 98
Testing effectiveness (Phase 2)Study completedNCT02489903
What this trial is testing

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

Who this might be right for
Small Cell CarcinomaCarcinoma, Non-Small-Cell LungNeuroendocrine Tumors+1 more
EpicentRx, Inc. 139
Early research (Phase 1)Looking for participantsNCT06586957
What this trial is testing

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorAdvanced Solid TumorSolid Tumor, Adult+25 more
NiKang Therapeutics, Inc. 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT03896503
What this trial is testing

Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaExtrapulmonary Small Cell Neuroendocrine CarcinomaLimited Stage Lung Small Cell Carcinoma+3 more
National Cancer Institute (NCI) 104
Testing effectiveness (Phase 2)Looking for participantsNCT06463665
What this trial is testing

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

Who this might be right for
Advanced Non-squamous Non-small-cell Lung CancerAdvanced Squamous Non-Small Cell Lung CarcinomaMetastatic Non-squamous Non Small Cell Lung Cancer+5 more
Genelux Corporation 142
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