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Results for “Platinum-Resistant Lung Small Cell Carcinoma”

45 trials

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Showing 20 of 45 results

Testing effectiveness (Phase 2)Study completedNCT00284141
What this trial is testing

Study of AVE0005 (VEGF Trap) in Locally Advanced or Metastatic Platinum- and Erlotinib- Resistant Non-small-cell-lung Adenocarcinoma

Who this might be right for
Pulmonary DiseasesNeoplasms, Lung
Sanofi 98
Testing effectiveness (Phase 2)Active Not RecruitingNCT04592237
What this trial is testing

Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer

Who this might be right for
Aggressive Variant Prostate CarcinomaCastration-Resistant Prostate CarcinomaMetastatic Prostate Carcinoma+3 more
M.D. Anderson Cancer Center 120
Testing effectiveness (Phase 2)Study completedNCT02489903
What this trial is testing

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

Who this might be right for
Small Cell CarcinomaCarcinoma, Non-Small-Cell LungNeuroendocrine Tumors+1 more
EpicentRx, Inc. 139
Testing effectiveness (Phase 2)Ended earlyNCT00509366
What this trial is testing

Study Using a Genomic Predictor of Platinum Resistance to Guide Therapy in Stage IIIB/IV Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Duke University 101
Testing effectiveness (Phase 2)Looking for participantsNCT05914116
What this trial is testing

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors
DualityBio Inc. 862
Testing effectiveness (Phase 2)Ended earlyNCT04971187
What this trial is testing

Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer

Who this might be right for
Locally Advanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+7 more
M.D. Anderson Cancer Center 3
Large-scale testing (Phase 3)Study completedNCT03924050
What this trial is testing

Toripalimab Plus Pemetrexed+Platinus in Advanced Non-small-cell Lungcancer Patients Previsouly Treated EGFR-TKI

Who this might be right for
Non-small Cell Lung Cancer
Shanghai Junshi Bioscience Co., Ltd. 440
Early research (Phase 1)Ended earlyNCT05274451
What this trial is testing

Investigate LYL797 in Adults With Solid Tumors

Who this might be right for
Triple Negative Breast CancerTNBC - Triple-Negative Breast CancerNon-small Cell Lung Cancer+20 more
Lyell Immunopharma, Inc. 57
Early research (Phase 1)Active Not RecruitingNCT03582475
What this trial is testing

Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate

Who this might be right for
Bladder Small Cell Neuroendocrine CarcinomaCastration-Resistant Prostate CarcinomaMetastatic Bladder Urothelial Carcinoma+14 more
Jonsson Comprehensive Cancer Center 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT05081609
What this trial is testing

Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+10 more
Ascendis Pharma Oncology Division A/S 320
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944772
What this trial is testing

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 247
Testing effectiveness (Phase 2)WithdrawnNCT01928160
What this trial is testing

Pemetrexed Disodium and Carboplatin or Cisplatin With or Without Erlotinib Hydrochloride in Treating Patient With Stage IV Non-Small Cell Lung Cancer Resistant to First-Line Therapy With Erlotinib Hydrochloride or Gefitinib

Who this might be right for
Recurrent Non-small Cell Lung CancerStage IV Non-small Cell Lung Cancer
Vanderbilt-Ingram Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT03319628
What this trial is testing

First-in-Human Study of XMT-1536 in Cancers Likely to Express NaPi2b

Who this might be right for
Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic
Mersana Therapeutics 523
Early research (Phase 1)Looking for participantsNCT06792552
What this trial is testing

A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsPlatinum Resistant Ovarian CancerFallopian Tube Cancer+5 more
NextCure, Inc. 738
Testing effectiveness (Phase 2)Looking for participantsNCT07306624
What this trial is testing

Nelmastobart in Combination With Docetaxel in Non Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
STCube, Inc. 62
Early research (Phase 1)Study completedNCT01363947
What this trial is testing

Safety and Pharmacokinetics of Escalating Doses of DNIB0600A in Participants With Non-Small Cell Lung Cancer (NSCLC) and Platinum Resistant Ovarian Cancer

Who this might be right for
Non-Small Cell Lung Cancer, Ovarian Cancer
Genentech, Inc. 87
Early research (Phase 1)Ended earlyNCT04244552
What this trial is testing

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Who this might be right for
Breast CancerColorectal CancerOvarian Cancer+13 more
Atreca, Inc. 87
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06724263
What this trial is testing

A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors

Who this might be right for
Recurrent Platinum-resistant Epithelial Ovarian CancerTriple Negative Breast Cancer (TNBC)Cervical Cancers+4 more
Tasly Biopharmaceuticals Co., Ltd. 120
Early research (Phase 1)Study completedNCT06517433
What this trial is testing

First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b

Who this might be right for
Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic
Mersana Therapeutics 62
Testing effectiveness (Phase 2)Ended earlyNCT04504916
What this trial is testing

Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)

Who this might be right for
Triple-negative Breast CancerNon-squamous Non-small-cell Lung CancerNSCLC+12 more
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 102
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