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Results for “Platinum-Resistant Lung Small Cell Carcinoma”

44 trials

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Showing 20 of 44 results

Testing effectiveness (Phase 2)Looking for participantsNCT06303505
What this trial is testing

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

Who this might be right for
Ovarian CancerNon-small Cell Lung Cancer
Tubulis GmbH 250
Testing effectiveness (Phase 2)Active Not RecruitingNCT04592237
What this trial is testing

Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer

Who this might be right for
Aggressive Variant Prostate CarcinomaCastration-Resistant Prostate CarcinomaMetastatic Prostate Carcinoma+3 more
M.D. Anderson Cancer Center 120
Testing effectiveness (Phase 2)WithdrawnNCT01928160
What this trial is testing

Pemetrexed Disodium and Carboplatin or Cisplatin With or Without Erlotinib Hydrochloride in Treating Patient With Stage IV Non-Small Cell Lung Cancer Resistant to First-Line Therapy With Erlotinib Hydrochloride or Gefitinib

Who this might be right for
Recurrent Non-small Cell Lung CancerStage IV Non-small Cell Lung Cancer
Vanderbilt-Ingram Cancer Center
Early research (Phase 1)Ended earlyNCT05274451
What this trial is testing

Investigate LYL797 in Adults With Solid Tumors

Who this might be right for
Triple Negative Breast CancerTNBC - Triple-Negative Breast CancerNon-small Cell Lung Cancer+20 more
Lyell Immunopharma, Inc. 57
Early research (Phase 1)Active Not RecruitingNCT05353439
What this trial is testing

Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaLimited Stage Lung Small Cell CarcinomaPlatinum-Resistant Lung Small Cell Carcinoma+3 more
National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03319628
What this trial is testing

First-in-Human Study of XMT-1536 in Cancers Likely to Express NaPi2b

Who this might be right for
Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic
Mersana Therapeutics 523
Large-scale testing (Phase 3)Looking for participantsNCT06829459
What this trial is testing

Evaluate the Efficacy and Safety of Glumetinib Combined With Osimertinib Mesylate Versus Platinum-based Doublet Chemotherapy in Non-Small Cell Lung Cancer Patients After Resistance to EGFR-TKIs

Who this might be right for
Non-Small Cell Lung Cancer
Shanghai JMT-Bio Inc. 350
Testing effectiveness (Phase 2)Ended earlyNCT02554812
What this trial is testing

Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)

Who this might be right for
Advanced Cancer
Pfizer 409
Early research (Phase 1)Looking for participantsNCT06586957
What this trial is testing

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorAdvanced Solid TumorSolid Tumor, Adult+25 more
NiKang Therapeutics, Inc. 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT03896503
What this trial is testing

Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaExtrapulmonary Small Cell Neuroendocrine CarcinomaLimited Stage Lung Small Cell Carcinoma+3 more
National Cancer Institute (NCI) 104
Testing effectiveness (Phase 2)Study completedNCT00116610
What this trial is testing

Picoplatin as Second-Line Therapy for Patients With Small Cell Lung Cancer

Who this might be right for
Small Cell Lung Cancer
Poniard Pharmaceuticals 75
Not applicableEnded earlyNCT05891197
What this trial is testing

A Biomarker Screening Protocol for Participants With Solid Tumors

Who this might be right for
Triple Negative Breast CancerNon-small Cell Lung CancerNon Small Cell Lung Cancer+19 more
Lyell Immunopharma, Inc. 10
Testing effectiveness (Phase 2)Study completedNCT02489903
What this trial is testing

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

Who this might be right for
Small Cell CarcinomaCarcinoma, Non-Small-Cell LungNeuroendocrine Tumors+1 more
EpicentRx, Inc. 139
Testing effectiveness (Phase 2)Study completedNCT00284141
What this trial is testing

Study of AVE0005 (VEGF Trap) in Locally Advanced or Metastatic Platinum- and Erlotinib- Resistant Non-small-cell-lung Adenocarcinoma

Who this might be right for
Pulmonary DiseasesNeoplasms, Lung
Sanofi 98
Large-scale testing (Phase 3)Study completedNCT03515837
What this trial is testing

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 492
Testing effectiveness (Phase 2)Active Not RecruitingNCT04607954
What this trial is testing

Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung Cancer

Who this might be right for
Platinum-Resistant Lung Small Cell CarcinomaPlatinum-Sensitive Lung Small Cell CarcinomaRecurrent Extensive Stage Lung Small Cell Carcinoma+1 more
Mayo Clinic 29
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06724263
What this trial is testing

A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors

Who this might be right for
Recurrent Platinum-resistant Epithelial Ovarian CancerTriple Negative Breast Cancer (TNBC)Cervical Cancers+4 more
Tasly Biopharmaceuticals Co., Ltd. 120
Testing effectiveness (Phase 2)Ended earlyNCT00509366
What this trial is testing

Study Using a Genomic Predictor of Platinum Resistance to Guide Therapy in Stage IIIB/IV Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Duke University 101
Early research (Phase 1)Ended earlyNCT06264921
What this trial is testing

A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorSolid Tumor, AdultAdvanced Solid Tumor+26 more
NiKang Therapeutics, Inc. 23
Early research (Phase 1)Looking for participantsNCT06242470
What this trial is testing

MGC026 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced CancerMetastatic Cancer+19 more
MacroGenics 250
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