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Results for “Pleomorphic Sarcoma, Undifferentiated”

59 trials

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Showing 20 of 59 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07817095
What this trial is testing

SBRT Combined With Reduced-Dose Anthracycline Chemotherapy and Toripalimab as Neoadjuvant Therapy for Localized High-Risk Undifferentiated Pleomorphic Sarcoma

Who this might be right for
Undifferentiated Pleomorphic Sarcoma (UPS)
Tianjin Medical University Cancer Institute and Hospital 39
Large-scale testing (Phase 3)WithdrawnNCT06370871
What this trial is testing

Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue Sarcoma

Who this might be right for
Advanced Soft Tissue SarcomaUndifferentiated Pleomorphic Sarcoma (UPS)Myxofibrosarcoma (MFS)
Boehringer Ingelheim
Early research (Phase 1)Study completedNCT03752398
What this trial is testing

XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)

Who this might be right for
Melanoma (Excluding Uveal Melanoma)Cervical CarcinomaPancreatic Carcinoma+13 more
Xencor, Inc. 198
Testing effectiveness (Phase 2)UnknownNCT04447274
What this trial is testing

Carilizumab in Combination With Apatinib in Subjects With Unresectable UPS and ASPS

Who this might be right for
Sarcoma
Chinese Academy of Medical Sciences 20
Early research (Phase 1)Study completedNCT04242238
What this trial is testing

Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas

Who this might be right for
SarcomaAdvanced SarcomaHigh Grade Sarcoma+4 more
Memorial Sloan Kettering Cancer Center 32
Testing effectiveness (Phase 2)Active Not RecruitingNCT05836571
What this trial is testing

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma

Who this might be right for
Locally Advanced Extraskeletal Myxoid ChondrosarcomaLocally Advanced LeiomyosarcomaLocally Advanced Liposarcoma+7 more
National Cancer Institute LAO 66
Testing effectiveness (Phase 2)Study completedNCT03123276
What this trial is testing

Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma

Who this might be right for
Sarcoma
Royal Marsden NHS Foundation Trust 25
Large-scale testing (Phase 3)Not Yet RecruitingNCT07823491
What this trial is testing

Pembrolizumab and Radiation Therapy With or Without Neoadjuvant Doxorubicin and Ifosfamide for the Treatment of High-Risk Resectable Undifferentiated Pleomorphic Sarcoma or Liposarcoma of the Extremity or Trunk Wall

Who this might be right for
Resectable LiposarcomaResectable Soft Tissue SarcomaResectable Undifferentiated Pleomorphic Sarcoma
Ohio State University Comprehensive Cancer Center 228
Early research (Phase 1)Looking for participantsNCT05711615
What this trial is testing

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Who this might be right for
Metastatic Dedifferentiated LiposarcomaMetastatic LeiomyosarcomaMetastatic Myxofibrosarcoma+9 more
National Cancer Institute (NCI) 30
Large-scale testing (Phase 3)Study completedNCT02180867
What this trial is testing

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Who this might be right for
Alveolar Soft Part SarcomaAngiomatoid Fibrous HistiocytomaAtypical Fibroxanthoma+33 more
National Cancer Institute (NCI) 140
Testing effectiveness (Phase 2)Ended earlyNCT01418001
What this trial is testing

Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)

Who this might be right for
SarcomaLeiomyosarcomaMalignant Peripheral Nerve Sheath Tumor+2 more
Memorial Sloan Kettering Cancer Center 5
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07741877
What this trial is testing

Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Soft Tissue Sarcoma

Who this might be right for
SarcomaSoft Tissue Sarcoma (STS)Advanced Soft Tissue Sarcoma+2 more
Iovance Biotherapeutics, Inc. 80
Testing effectiveness (Phase 2)Ended earlyNCT05017103
What this trial is testing

Sintilimab for the Treatment of Locally Advanced, Metastatic, Recurrent, or Unresectable Undifferentiated Pleomorphic Sarcoma, SiARa Cancer Study

Who this might be right for
Locally Advanced Undifferentiated Pleomorphic SarcomaMetastatic Undifferentiated Pleomorphic SarcomaRecurrent Undifferentiated Pleomorphic Sarcoma+1 more
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT03899805
What this trial is testing

A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas

Who this might be right for
SarcomaLiposarcomaLeiomyosarcoma+1 more
Dana-Farber Cancer Institute 57
Testing effectiveness (Phase 2)Active Not RecruitingNCT03449108
What this trial is testing

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

Who this might be right for
Bone SarcomaDedifferentiated ChondrosarcomaGiant Cell Tumor of Bone+13 more
M.D. Anderson Cancer Center 30
Not applicableLooking for participantsNCT04055220
What this trial is testing

Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas

Who this might be right for
Bone SarcomaOsteosarcomaEwing Sarcoma+4 more
Centre Leon Berard 168
Testing effectiveness (Phase 2)UnknownNCT03651375
What this trial is testing

Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall

Who this might be right for
SarcomaFibrosarcomaLeiomyosarcoma+14 more
Maria Sklodowska-Curie National Research Institute of Oncology 46
Not applicableStudy completedNCT04008238
What this trial is testing

Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients

Who this might be right for
Soft Tissue Sarcoma AdultUndifferentiated Pleomorphic SarcomaEpithelioid Sarcoma+4 more
Institut Bergonié 29
Testing effectiveness (Phase 2)UnknownNCT04356872
What this trial is testing

The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue Sarcoma

Who this might be right for
Sarcoma, Soft Tissue
Fudan University 45
Early research (Phase 1)Active Not RecruitingNCT04420975
What this trial is testing

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

Who this might be right for
LeiomyosarcomaMalignant Peripheral Nerve Sheath TumorMyxofibrosarcoma+27 more
Jonsson Comprehensive Cancer Center 14
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