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Results for “Plexiform Neurofibroma Associated With Neurofibromatosis Type 1”

11 trials

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Showing 11 of 11 results

Testing effectiveness (Phase 2)Study completedNCT03326388
What this trial is testing

Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaOptic Nerve Glioma
Great Ormond Street Hospital for Children NHS Foundation Trust 14
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06763315
What this trial is testing

Low-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children

Who this might be right for
Plexiform Neurofibromas (PN)
West China Hospital 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT03962543
What this trial is testing

MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas

Who this might be right for
Plexiform NeurofibromaNeurofibromatosis Type 1 (NF1)
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany 114
Testing effectiveness (Phase 2)Study completedNCT03231306
What this trial is testing

Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Plexiform Neurofibroma
University of Alabama at Birmingham 45
Testing effectiveness (Phase 2)WithdrawnNCT05825365
What this trial is testing

Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromasPost-operative
AstraZeneca
Not applicableAvailableNCT05028166
What this trial is testing

Individual Patient Compassionate Use of Mirdametinib

Who this might be right for
Neurofibromatosis Type 1-Associated Plexiform NeurofibromasHistiocytic NeoplasmOther MAP-K Pathway Driven Diseases
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany
Not applicableActive Not RecruitingNCT06175637
What this trial is testing

Observational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNs

Who this might be right for
Neurofibroma, Plexiform
AstraZeneca 409
Testing effectiveness (Phase 2)Ended earlyNCT01365468
What this trial is testing

Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)

Who this might be right for
Plexiform Neurofibroma Associated With Neurofibromatosis Type 1
Novartis Pharmaceuticals 9
Early research (Phase 1)Looking for participantsNCT02390752
What this trial is testing

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Who this might be right for
Neurofibroma, PlexiformPrecursor Cell Lymphoblastic Leukemia-LymphomaLeukemia, Promyelocytic, Acute+1 more
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)Study completedNCT02096471
What this trial is testing

MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1

Who this might be right for
Neurofibromatosis Type 1 and Growing or Symptomatic, Inoperable PN
University of Alabama at Birmingham 19
Large-scale testing (Phase 3)Looking for participantsNCT07407803
What this trial is testing

Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas

Who this might be right for
Plexiform Neurofibroma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 177