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Results for “Polymyxin B”

34 trials

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Showing 20 of 34 results

Testing effectiveness (Phase 2)Study completedNCT05685615
What this trial is testing

PK of BV100 in Patients VABP Suspected or Confirmed to Be Due to CRAB

Who this might be right for
Ventilator Associated Pneumonia
BioVersys AG 39
Not applicableEnded earlyNCT02871024
What this trial is testing

Efficacy of Polymyxin B Hemoperfusion on Severe Sepsis Secondary to Pneumonia or Urinary Tract Infection

Who this might be right for
Sepsis
National Taiwan University Hospital 1
Large-scale testing (Phase 3)UnknownNCT03159078
What this trial is testing

Polymyxin B Monotherapy vs Combination Therapy in Critically Ill Patients With Multi-drug Resistant Pathogens

Who this might be right for
TraumaResistant InfectionCritical Illness
University of Puerto Rico 40
Early research (Phase 1)Study completedNCT05359627
What this trial is testing

A Pharmacokinetic Study of Polymyxin B in Healthy Subjects and Subjects With Renal Insufficiency

Who this might be right for
Antibiotic Toxicity
TTY Biopharm 22
Testing effectiveness (Phase 2)Ended earlyNCT03725267
What this trial is testing

Melatonin for Renal Protection in Patients Receiving Polymyxin B

Who this might be right for
Acute Kidney InjuryMelatoninPolymyxin B Adverse Reaction
Hospital de Clinicas de Porto Alegre 88
Not applicableTemporarily Not AvailableNCT02825329
What this trial is testing

Open-label Evaluation of Polymyxin B Hemoperfusion for Septic Shock

Who this might be right for
Septic ShockEndotoxemia
Spectral Diagnostics (US) Inc.
Large-scale testing (Phase 3)Study completedNCT00490477
What this trial is testing

The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial

Who this might be right for
Gram-Negative Bacterial InfectionsSepsis
University of Turin, Italy 16
Not applicableLooking for participantsNCT06966284
What this trial is testing

A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial Infection

Who this might be right for
Bacteremia Caused by Gram-Negative BacteriaBacterial Pneumonia
TTY Biopharm 480
Not applicableStudy completedNCT02682355
What this trial is testing

Optimizing Clinical Use of Polymyxin B

Who this might be right for
PneumoniaBlood Stream InfectionUrinary Tract Infections+2 more
Rutgers, The State University of New Jersey 155
Early research (Phase 1)Looking for participantsNCT07580586
What this trial is testing

A Single Centre, Open-label, 2-period Fixed-sequence, Phase I Clinical Study to Evaluate the Effect of BV100 on the Pharmacokinetics of Polymyxin B in Healthy Volunteers

Who this might be right for
Healthy Adult Participants
BioVersys SAS 16
Post-approval studies (Phase 4)Study completedNCT00629382
What this trial is testing

Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis

Who this might be right for
Gram-Negative Bacterial InfectionsSepsisSeptic Shock
St. Bortolo Hospital 70
Testing effectiveness (Phase 2)Looking for participantsNCT07759934
What this trial is testing

ASK0912 Versus Polymyxin B for Injection in Adults With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia

Who this might be right for
Ventilator-associated Bacterial Pneumonia (VABP)Hospital-acquired Bacterial Pneumonia (HABP)
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 60
Large-scale testing (Phase 3)Study completedNCT01222663
What this trial is testing

Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock

Who this might be right for
PeritonitisSeptic Shock
Meditor SAS 243
Not applicableUnknownNCT04970537
What this trial is testing

Efficacy Analysis of Tigecycline-based Therapy and Polymyxin B-based Therapy in ICU Infection

Who this might be right for
TigecyclinePolymyxin BIntensive Care Unit
Xiangya Hospital of Central South University 800
Not applicableStudy completedNCT02413541
What this trial is testing

The Pilot Study of the Efficacy of Polymyxin-B Hemoperfusion in Critically Ill Patients With Severe Sepsis

Who this might be right for
Severe Sepsis
Chulalongkorn University 90
Large-scale testing (Phase 3)UnknownNCT01227863
What this trial is testing

Efficacy Maxinom® And Maxitrol® in Reducing The Signs And Symptoms Of Acute Bacterial Conjunctivitis

Who this might be right for
Bacterial ConjunctivitisAcute
Azidus Brasil 70
Large-scale testing (Phase 3)Looking for participantsNCT07326540
What this trial is testing

Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex

Who this might be right for
Hospital Acquired Bacterial Pneumonia (HABP)Ventilator Associated Bacterial Pneumonia (VABP)Colistin Resistanrt ABC+1 more
BioVersys SAS
Early research (Phase 1)Not Yet RecruitingNCT07502144
What this trial is testing

A Phase I Study Comparing the Safety, Pharmacokinetics and Renal Effects of VRP-034 and Marketed Polymyxin B in Healthy Volunteers

Who this might be right for
Healthy Volunteers
Venus Remedies Limited 48
Not applicableStudy completedNCT01646229
What this trial is testing

Impact of Early Peri-operative Use of Polymyxin-B Hemoperfusion in Septic Patients Undergoing Emergent Abdominal Surgery

Who this might be right for
Abdominal SepsisPeritonitisColon Perforation
University Hospital, Geneva 28
Not applicableStudy completedNCT01046669
What this trial is testing

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock

Who this might be right for
Septic ShockEndotoxemia
Spectral Diagnostics (US) Inc. 450
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