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Results for “Polymyxin B”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Study completedNCT05685615
What this trial is testing

PK of BV100 in Patients VABP Suspected or Confirmed to Be Due to CRAB

Who this might be right for
Ventilator Associated Pneumonia
BioVersys AG 39
Not applicableEnded earlyNCT02871024
What this trial is testing

Efficacy of Polymyxin B Hemoperfusion on Severe Sepsis Secondary to Pneumonia or Urinary Tract Infection

Who this might be right for
Sepsis
National Taiwan University Hospital 1
Large-scale testing (Phase 3)Study completedNCT01429701
What this trial is testing

Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol in Acute and Sub-acute Dermatitis Eczematous

Who this might be right for
Eczema
EMS 76
Not applicableLooking for participantsNCT06595979
What this trial is testing

Intraventricular Administration of Intracranial Infections Caused by （Carbapenem-resistant Gram-negative Bacilli）CRGNB

Who this might be right for
Intracranial Infections
Second Affiliated Hospital, School of Medicine, Zhejiang University 222
Large-scale testing (Phase 3)UnknownNCT01227863
What this trial is testing

Efficacy Maxinom® And Maxitrol® in Reducing The Signs And Symptoms Of Acute Bacterial Conjunctivitis

Who this might be right for
Bacterial ConjunctivitisAcute
Azidus Brasil 70
Post-approval studies (Phase 4)Study completedNCT00629382
What this trial is testing

Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis

Who this might be right for
Gram-Negative Bacterial InfectionsSepsisSeptic Shock
St. Bortolo Hospital 70
Not applicableLooking for participantsNCT07086391
What this trial is testing

Different Methods of Aerosolized Polymyxin B Inhalation for Treating Carbapenem-Resistant Gram-Negative Bacterial Pneumonia.

Who this might be right for
Carbapenem-Resistant Enterobacteriaceae InfectionPneumonia - Bacterial
Fujian Medical University Union Hospital 144
Post-approval studies (Phase 4)UnknownNCT02328183
What this trial is testing

Efficacy of Polymyxin B Against Infections Caused by Extensively Drug-resistant (XDR) Gram-Negative Bacteria

Who this might be right for
Hospital Infection
Mahidol University 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07431307
What this trial is testing

Safety, Pharmacokinetics and Efficacy of BV100 Plus Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol in Patients With Pulmonary and Extrapulmonary Infections Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex

Who this might be right for
Ventilator Associated Bacterial Pneumonia (VABP)Hospital Acquired Bacterial Pneumonia (HABP)Blood Stream Infection+2 more
BioVersys AG
Large-scale testing (Phase 3)Not Yet RecruitingNCT07326540
What this trial is testing

Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex

Who this might be right for
Hospital Acquired Bacterial Pneumonia (HABP)Ventilator Associated Bacterial Pneumonia (VABP)Colistin Resistanrt ABC+1 more
BioVersys SAS
Not applicableStudy completedNCT01646229
What this trial is testing

Impact of Early Peri-operative Use of Polymyxin-B Hemoperfusion in Septic Patients Undergoing Emergent Abdominal Surgery

Who this might be right for
Abdominal SepsisPeritonitisColon Perforation
University Hospital, Geneva 28
Not applicableUnknownNCT06076603
What this trial is testing

Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients

Who this might be right for
Polymyxin BVentilator-associated PneumoniaMultidrug Resistant Bacterial Infection+1 more
Southeast University, China 30
Not applicableTemporarily Not AvailableNCT02825329
What this trial is testing

Open-label Evaluation of Polymyxin B Hemoperfusion for Septic Shock

Who this might be right for
Septic ShockEndotoxemia
Spectral Diagnostics (US) Inc.
Early research (Phase 1)Study completedNCT05359627
What this trial is testing

A Pharmacokinetic Study of Polymyxin B in Healthy Subjects and Subjects With Renal Insufficiency

Who this might be right for
Antibiotic Toxicity
TTY Biopharm 22
Not applicableLooking for participantsNCT06966284
What this trial is testing

A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial Infection

Who this might be right for
Bacteremia Caused by Gram-Negative BacteriaBacterial Pneumonia
TTY Biopharm 480
Large-scale testing (Phase 3)Study completedNCT01222663
What this trial is testing

Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock

Who this might be right for
PeritonitisSeptic Shock
Meditor SAS 243
Large-scale testing (Phase 3)Study completedNCT00490477
What this trial is testing

The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial

Who this might be right for
Gram-Negative Bacterial InfectionsSepsis
University of Turin, Italy 16
Not applicableStudy completedNCT01948778
What this trial is testing

The Effects of a Polyethyleneimine-coated Membrane (oXiris™) for Hemofiltration Versus Polymyxin B- Immobilized Fibre Column (Toraymyxin™) for Hemoperfusion on Endotoxin Activity and Inflammatory Conditions in Septic Shock- A Randomized Controlled Pilot Study (ENDoX-study)

Who this might be right for
Patients in Septic Shock
University of Zurich 38
Not applicableStudy completedNCT00000635
What this trial is testing

Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine

Who this might be right for
Herpes SimplexHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 25
Early research (Phase 1)Not Yet RecruitingNCT07502144
What this trial is testing

A Phase I Study Comparing the Safety, Pharmacokinetics and Renal Effects of VRP-034 and Marketed Polymyxin B in Healthy Volunteers

Who this might be right for
Healthy Volunteers
Venus Remedies Limited 48
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