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Results for “Polymyxin B”

32 trials

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Showing 20 of 32 results

Early research (Phase 1)Looking for participantsNCT07580586
What this trial is testing

A Single Centre, Open-label, 2-period Fixed-sequence, Phase I Clinical Study to Evaluate the Effect of BV100 on the Pharmacokinetics of Polymyxin B in Healthy Volunteers

Who this might be right for
Healthy Adult Participants
BioVersys SAS 16
Not applicableLooking for participantsNCT06595979
What this trial is testing

Intraventricular Administration of Intracranial Infections Caused by （Carbapenem-resistant Gram-negative Bacilli）CRGNB

Who this might be right for
Intracranial Infections
Second Affiliated Hospital, School of Medicine, Zhejiang University 222
Not applicableActive Not RecruitingNCT03901807
What this trial is testing

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study

Who this might be right for
Septic ShockEndotoxemia
Spectral Diagnostics (US) Inc. 150
Large-scale testing (Phase 3)UnknownNCT01227863
What this trial is testing

Efficacy Maxinom® And Maxitrol® in Reducing The Signs And Symptoms Of Acute Bacterial Conjunctivitis

Who this might be right for
Bacterial ConjunctivitisAcute
Azidus Brasil 70
Large-scale testing (Phase 3)Study completedNCT01222663
What this trial is testing

Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock

Who this might be right for
PeritonitisSeptic Shock
Meditor SAS 243
Not applicableLooking for participantsNCT06966284
What this trial is testing

A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial Infection

Who this might be right for
Bacteremia Caused by Gram-Negative BacteriaBacterial Pneumonia
TTY Biopharm 480
Testing effectiveness (Phase 2)Ended earlyNCT03725267
What this trial is testing

Melatonin for Renal Protection in Patients Receiving Polymyxin B

Who this might be right for
Acute Kidney InjuryMelatoninPolymyxin B Adverse Reaction
Hospital de Clinicas de Porto Alegre 88
Large-scale testing (Phase 3)UnknownNCT03159078
What this trial is testing

Polymyxin B Monotherapy vs Combination Therapy in Critically Ill Patients With Multi-drug Resistant Pathogens

Who this might be right for
TraumaResistant InfectionCritical Illness
University of Puerto Rico 40
Large-scale testing (Phase 3)Study completedNCT01429701
What this trial is testing

Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol in Acute and Sub-acute Dermatitis Eczematous

Who this might be right for
Eczema
EMS 76
Not applicableLooking for participantsNCT07086391
What this trial is testing

Different Methods of Aerosolized Polymyxin B Inhalation for Treating Carbapenem-Resistant Gram-Negative Bacterial Pneumonia.

Who this might be right for
Carbapenem-Resistant Enterobacteriaceae InfectionPneumonia - Bacterial
Fujian Medical University Union Hospital 144
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07431307
What this trial is testing

Safety, Pharmacokinetics and Efficacy of BV100 Plus Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol in Patients With Pulmonary and Extrapulmonary Infections Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex

Who this might be right for
Ventilator Associated Bacterial Pneumonia (VABP)Hospital Acquired Bacterial Pneumonia (HABP)Blood Stream Infection+2 more
BioVersys AG
Not applicableStudy completedNCT01046669
What this trial is testing

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock

Who this might be right for
Septic ShockEndotoxemia
Spectral Diagnostics (US) Inc. 450
Post-approval studies (Phase 4)UnknownNCT02328183
What this trial is testing

Efficacy of Polymyxin B Against Infections Caused by Extensively Drug-resistant (XDR) Gram-Negative Bacteria

Who this might be right for
Hospital Infection
Mahidol University 100
Not applicableStudy completedNCT00000635
What this trial is testing

Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine

Who this might be right for
Herpes SimplexHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 25
Not applicableUnknownNCT03177330
What this trial is testing

Safety and Efficacy of Heparin Dosing Score Protocol for Polymyxin-B Hemoperfusion

Who this might be right for
Septic ShockPolymyxin B Hemoperfusion
National Taiwan University Hospital 30
Early research (Phase 1)Not Yet RecruitingNCT07502144
What this trial is testing

A Phase I Study Comparing the Safety, Pharmacokinetics and Renal Effects of VRP-034 and Marketed Polymyxin B in Healthy Volunteers

Who this might be right for
Healthy Volunteers
Venus Remedies Limited 48
Not applicableStudy completedNCT02413541
What this trial is testing

The Pilot Study of the Efficacy of Polymyxin-B Hemoperfusion in Critically Ill Patients With Severe Sepsis

Who this might be right for
Severe Sepsis
Chulalongkorn University 90
Not applicableUnknownNCT06076603
What this trial is testing

Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients

Who this might be right for
Polymyxin BVentilator-associated PneumoniaMultidrug Resistant Bacterial Infection+1 more
Southeast University, China 30
Large-scale testing (Phase 3)Study completedNCT00490477
What this trial is testing

The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial

Who this might be right for
Gram-Negative Bacterial InfectionsSepsis
University of Turin, Italy 16
Testing effectiveness (Phase 2)Study completedNCT05685615
What this trial is testing

PK of BV100 in Patients VABP Suspected or Confirmed to Be Due to CRAB

Who this might be right for
Ventilator Associated Pneumonia
BioVersys AG 39
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