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Results for “Pontine Diffuse Midline Glioma”

44 trials

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Showing 20 of 44 results

Early research (Phase 1)Looking for participantsNCT07076498
What this trial is testing

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Who this might be right for
Glioma
M.D. Anderson Cancer Center 20
Testing effectiveness (Phase 2)Looking for participantsNCT07589257
What this trial is testing

VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine Glioma
Guangzhou Virotech Pharmaceutical Co., Ltd. 10
Not applicableNot Yet RecruitingNCT06093165
What this trial is testing

RE-irradiation of Diffuse MIdline Glioma paTients

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine GliomaDiffuse Glioma+3 more
Rigshospitalet, Denmark 59
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07767110
What this trial is testing

Targeted LSAM-Cisplatin Infusion in Gliomas, Evaluation of Response

Who this might be right for
Diffuse Midline Glioma (DMG)Diffuse Intrinsic Pontine Glioma (DIPG)Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma
NanOlogy, LLC 20
Early research (Phase 1)Ended earlyNCT04771897
What this trial is testing

BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Bexion Pharmaceuticals, Inc. 10
Testing effectiveness (Phase 2)Ended earlyNCT02758366
What this trial is testing

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Who this might be right for
Glioblastoma (GBM)DIPGBrainstem Glioma, Pediatric+5 more
Meyer Children's Hospital IRCCS 21
Early research (Phase 1)Study completedNCT01922076
What this trial is testing

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligoastrocytomaDiffuse Intrinsic Pontine Glioma+3 more
National Cancer Institute (NCI) 46
Not applicableLooking for participantsNCT06140719
What this trial is testing

XPedite: A Study to Expedite DIPG and DMG Research

Who this might be right for
OncologyDIPGDMG
xCures 400
Not applicableNo Longer AvailableNCT05518838
What this trial is testing

Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-altered

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine Glioma
Oblato, Inc.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07562971
What this trial is testing

Focused Ultrasound Blood-Brain Barrier Opening in Pontine Diffuse Midline Glioma to Enhance Temozolomide Therapy: Pilot Feasibility Study (FIDES)

Who this might be right for
Diffuse Midline Glioma, H3 K27-Altered
UMC Utrecht 20
Early research (Phase 1)Looking for participantsNCT05298995
What this trial is testing

GD2-CAR T Cells for Pediatric Brain Tumours

Who this might be right for
Brain Tumor, PediatricMedulloblastoma, ChildhoodEmbryonal Tumor+4 more
Bambino Gesù Hospital and Research Institute 54
Very early researchWithdrawnNCT04051047
What this trial is testing

Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma

Who this might be right for
Glial Tumor of BrainDiffuse Intrinsic Pontine GliomaGlioma
University of Michigan Rogel Cancer Center
Early research (Phase 1)Looking for participantsNCT05762419
What this trial is testing

FUS Etoposide for DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Columbia University 10
Early research (Phase 1)Looking for participantsNCT04196413
What this trial is testing

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)

Who this might be right for
Glioma of Spinal CordGlioma of Brainstem
Stanford University 97
Early research (Phase 1)Active Not RecruitingNCT06894979
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group 54
Testing effectiveness (Phase 2)Study completedNCT02960230
What this trial is testing

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGliomaDiffuse Midline Glioma, H3 K27M-Mutant
Sabine Mueller, MD, PhD 50
Early research (Phase 1)Looking for participantsNCT06305910
What this trial is testing

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantRecurrent High Grade Glioma
OX2 Therapeutics 24
Large-scale testing (Phase 3)UnknownNCT03243461
What this trial is testing

International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)

Who this might be right for
Glioblastoma WHO Grade IVDiffuse Midline Glioma Histone 3 K27M WHO Grade IVAnaplastic Astrocytoma WHO Grade III+2 more
University of Göttingen 167
Early research (Phase 1)Study completedNCT04264143
What this trial is testing

CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Pontine and Thalamic GliomasDiffuse Midline Glioma
Luca Szalontay 9
Not applicableLooking for participantsNCT03101813
What this trial is testing

International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantDiffuse Midline Glioma
Children's Hospital Medical Center, Cincinnati 1,500
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