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Results for “Pontine Diffuse Midline Glioma”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT04943848
What this trial is testing

RHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Ann & Robert H Lurie Children's Hospital of Chicago 36
Large-scale testing (Phase 3)Looking for participantsNCT05476939
What this trial is testing

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantDiffuse Midline Glioma, H3K27-altered
Gustave Roussy, Cancer Campus, Grand Paris 433
Testing effectiveness (Phase 2)Temporarily pausedNCT06639607
What this trial is testing

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Who this might be right for
Diffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more
Washington University School of Medicine 68
Early research (Phase 1)Ended earlyNCT04804709
What this trial is testing

Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Pontine and Thalamic GliomasDiffuse Midline Glioma, H3 K27M-Mutant
Columbia University 5
Not applicableStudy completedNCT01878266
What this trial is testing

Prospective Trial of Two Hypofractionated Radiotherapy Regimens Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children

Who this might be right for
Pediatric Brain Stem Glioma
Children's Cancer Hospital Egypt 57357 119
Very early researchLooking for participantsNCT06333899
What this trial is testing

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 15
Not applicableNo Longer AvailableNCT06439849
What this trial is testing

Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline Glioma

Who this might be right for
DIPG Brain TumorDiffuse Brainstem GliomaH3 K27M+2 more
Petrov, Andrey
Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Testing effectiveness (Phase 2)Looking for participantsNCT05009992
What this trial is testing

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantRecurrent Diffuse Intrinsic Pontine Glioma+3 more
University of California, San Francisco 360
Early research (Phase 1)Not Yet RecruitingNCT07331064
What this trial is testing

Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor

Who this might be right for
High Grade GliomasAtypical Teratoid Rhabdoid Tumors (ATRT)Diffuse Midline Glioma+2 more
Sarah Rumler 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07501156
What this trial is testing

H3K27M-specific Immune Effector Cells Targeting DMG/DIPG

Who this might be right for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma
Shenzhen Geno-Immune Medical Institute 30
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Testing effectiveness (Phase 2)Looking for participantsNCT04870944
What this trial is testing

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Who this might be right for
Diffuse Midline Glioma, H3 K27-AlteredMetastatic Malignant Neoplasm in the Central Nervous SystemRecurrent Diffuse Intrinsic Pontine Glioma+7 more
Children's Oncology Group 63
Early research (Phase 1)Looking for participantsNCT06624371
What this trial is testing

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

Who this might be right for
High-grade GliomaMedulloblastomaDiffuse Intrinsic Pontine Glioma+1 more
Emory University 18
Early research (Phase 1)Study completedNCT03696355
What this trial is testing

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
St. Jude Children's Research Hospital 27
Testing effectiveness (Phase 2)Temporarily pausedNCT05123534
What this trial is testing

Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma
SonALAsense, Inc. 15
Testing effectiveness (Phase 2)Ended earlyNCT05500508
What this trial is testing

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Who this might be right for
CancerSolid TumorSolid Carcinoma+17 more
Aminex Therapeutics, Inc. 15
Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Testing effectiveness (Phase 2)Looking for participantsNCT07680439
What this trial is testing

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

Who this might be right for
Diffuse Intrinsic Pontine GliomaDIPGBrain Tumor+9 more
BrainChild Bio, Inc 75
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
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