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Results for “Porphyria”

67 trials

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Showing 20 of 67 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06144840
What this trial is testing

INcreased Sun Exposure Without Pain In Research Participants With EPP or XLP

Who this might be right for
Erythropoietic Protoporphyria (EPP)X-Linked Protoporphyria (XLP)
Tanabe Pharma America, Inc. 165
Not applicableStudy completedNCT00006057
What this trial is testing

Diagnostic and Screening Study of Genetic Disorders

Who this might be right for
Tay-Sachs DiseasePorphyria, ErythropoieticLeukodystrophy, Globoid Cell+1 more
National Center for Research Resources (NCRR) 50
Not applicableStudy completedNCT02979249
What this trial is testing

Oral Iron for Erythropoietic Protoporphyrias

Who this might be right for
Erythropoietic ProtoporphyriaEPPX-linked Protoporphyria+1 more
Icahn School of Medicine at Mount Sinai 16
Not applicableEnded earlyNCT01550705
What this trial is testing

Effect of Isoniazid on Protoporphyrin Levels in Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria (EPP)X Linked Erythropoietic Protoporphyria
University of Utah 11
Testing effectiveness (Phase 2)Ended earlyNCT02922413
What this trial is testing

Panhematin for Prevention of Acute Attacks of Porphyria

Who this might be right for
Acute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria
The University of Texas Medical Branch, Galveston 13
Testing effectiveness (Phase 2)Study completedNCT05308472
What this trial is testing

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

Who this might be right for
Erythropoietic Protoporphyria
Disc Medicine, Inc 75
Large-scale testing (Phase 3)Study completedNCT00599326
What this trial is testing

Pilot Trial of Deferasirox in the Treatment of Porphyria Cutanea Tarda

Who this might be right for
Porphyria Cutanea Tarda
University of Texas Southwestern Medical Center 10
Early research (Phase 1)Study completedNCT02452372
What this trial is testing

Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)

Who this might be right for
Acute Intermittent Porphyria
Alnylam Pharmaceuticals 40
Not applicableStudy completedNCT02240784
What this trial is testing

EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)

Who this might be right for
Acute Hepatic Porphyria
Alnylam Pharmaceuticals 136
Testing effectiveness (Phase 2)Study completedNCT00004789
What this trial is testing

Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria

Who this might be right for
Porphyria
National Center for Research Resources (NCRR) 59
Not applicableStudy completedNCT00004330
What this trial is testing

Studies in Porphyria IV: Gonadotropin-Releasing Hormone (GnRH) Analogues for Prevention of Cyclic Attacks

Who this might be right for
Porphyria
National Center for Research Resources (NCRR)
Not applicableApproved For MarketingNCT04056481
What this trial is testing

Expanded Access Protocol of Givosiran for Patients With Acute Hepatic Porphyria

Who this might be right for
Acute Hepatic Porphyria
Alnylam Pharmaceuticals
Not applicableStudy completedNCT05882136
What this trial is testing

Acute Intermittent Porphyria Related Abnormalities in Cardiovascular System

Who this might be right for
Porphyrias, Hepatic
National Institute of Cardiology, Warsaw, Poland 180
Not applicableStudy completedNCT01880983
What this trial is testing

Mitoferrin-1 Expression in Erythropoietic Protoporphyria (Porphyria Rare Disease Clinical Research Consortium (RDCRC))

Who this might be right for
Erythropoietic Protoporphyria (EPP)
University of Alabama at Birmingham 150
Testing effectiveness (Phase 2)Study completedNCT00004396
What this trial is testing

Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias

Who this might be right for
Porphyria
National Center for Research Resources (NCRR) 32
Large-scale testing (Phase 3)Study completedNCT04578496
What this trial is testing

A Safety Extension Study in Patients With Erythropoietic Protoporphyria (EPP)

Who this might be right for
Erythropoietic Protoporphyria
Clinuvel Pharmaceuticals Limited 16
Large-scale testing (Phase 3)Study completedNCT00004940
What this trial is testing

Phase III Study of L-Cysteine in Patients With Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria
Brigham and Women's Hospital 50
Large-scale testing (Phase 3)Study completedNCT04053270
What this trial is testing

Multicentre Phase III Erythropoietic Protoporphyria Study

Who this might be right for
Erythropoietic Protoporphyria
Clinuvel Pharmaceuticals Limited 100
Not applicableLooking for participantsNCT05502133
What this trial is testing

Identification of Acute Intermittent Porphyria Modifying Genes

Who this might be right for
Acute Intermittent Porphyria (AIP)
Icahn School of Medicine at Mount Sinai 150
Not applicableStudy completedNCT01688895
What this trial is testing

Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact

Who this might be right for
Erythropoietic ProtoporphyriaEPPX-Linked Protoporphyria+5 more
Icahn School of Medicine at Mount Sinai 150
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