Not applicableStudy completedNCT03906214What this trial is testingEvidence-based Assessment of Medication Sensitivity in Acute Hepatic PorphyriaWho this might be right forPorphyrias University of South Florida 60
Not applicableLooking for participantsNCT01561157What this trial is testingLongitudinal Study of the PorphyriasWho this might be right forAcute PorphyriasCutaneous Porphyrias The American Porphyrias Expert Collaborative 1,500
Not applicableActive Not RecruitingNCT02935400What this trial is testingAcute Porphyria Biomarkers for Disease ActivityWho this might be right forAcute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria The University of Texas Medical Branch, Galveston 50
Not applicableLooking for participantsNCT05502133What this trial is testingIdentification of Acute Intermittent Porphyria Modifying GenesWho this might be right forAcute Intermittent Porphyria (AIP) Icahn School of Medicine at Mount Sinai 150
Early research (Phase 1)Study completedNCT03505853What this trial is testingInvestigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP)Who this might be right forAcute Intermittent Porphyria (AIP)Acute Hepatic Porphyria (AHP)Porphyria, Acute Intermittent+1 more Alnylam Pharmaceuticals 10
Testing effectiveness (Phase 2)Study completedNCT00004789What this trial is testingPhase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute PorphyriaWho this might be right forPorphyria National Center for Research Resources (NCRR) 59
Not applicableUnknownNCT01617642What this trial is testingDental Health, Diet, Inflammation and Biomarkers in Patients With Acute Intermittent Porphyria(AIP)Who this might be right forAcute Intermittent Porphyria Nordlandssykehuset HF 100
Testing effectiveness (Phase 2)Study completedNCT02949830What this trial is testingEvaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)Who this might be right forAcute Intermittent Porphyria Alnylam Pharmaceuticals 16
Large-scale testing (Phase 3)Study completedNCT03338816What this trial is testingENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)Who this might be right forAcute Hepatic PorphyriaAcute Intermittent PorphyriaPorphyria, Acute Intermittent+4 more Alnylam Pharmaceuticals 94
Early research (Phase 1)Study completedNCT02943213What this trial is testingAssessment of Intra-subject Variability in the Bioavailability of Chlorpromazine HydrochlorideWho this might be right forAnti-PsychoticManagement of Manifestations of Psychotic DisordersTreatment of Schizophrenia+6 more Cycle Pharmaceuticals Ltd. 20
Testing effectiveness (Phase 2)Study completedNCT02180412What this trial is testingControlled Trial of Panhematin in Treatment of Acute Attacks of PorphyriaWho this might be right forAcute Porphyrias The University of Texas Medical Branch, Galveston 20
Early research (Phase 1)Study completedNCT02082860What this trial is testingPhase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent PorphyriaWho this might be right forAcute Intermittent Porphyria Digna Biotech S.L. 8
Not applicableStudy completedNCT05882136What this trial is testingAcute Intermittent Porphyria Related Abnormalities in Cardiovascular SystemWho this might be right forPorphyrias, Hepatic National Institute of Cardiology, Warsaw, Poland 180
Not applicableStudy completedNCT02076763What this trial is testingObservational Study of Acute Intermittent Porphyria PatientsWho this might be right forAcute Intermittent Porphyria Digna Biotech S.L. 9
Not applicableEnded earlyNCT03547297What this trial is testingINSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHPWho this might be right forAcute Hepatic PorphyriaHepatic PorphyriasAcute Intermittent Porphyria (AIP)+4 more Alnylam Pharmaceuticals 212
Testing effectiveness (Phase 2)Ended earlyNCT02922413What this trial is testingPanhematin for Prevention of Acute Attacks of PorphyriaWho this might be right forAcute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria The University of Texas Medical Branch, Galveston 13
Early research (Phase 1)Study completedNCT02452372What this trial is testingGivosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)Who this might be right forAcute Intermittent Porphyria Alnylam Pharmaceuticals 40
Not applicableLooking for participantsNCT06273644What this trial is testingClinical Research on Acute Intermittent Porphyria and the Use of Carbohydrate-Rich Diet as a TreatmentWho this might be right forPorphyria, Acute Intermittent Nordlandssykehuset HF 50
Not applicableApproved For MarketingNCT04056481What this trial is testingExpanded Access Protocol of Givosiran for Patients With Acute Hepatic PorphyriaWho this might be right forAcute Hepatic Porphyria Alnylam Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT00418795What this trial is testingPorphozym in the Treatment of Acute Attacks in AIPWho this might be right forAcute Intermittent Porphyria Zymenex A/S 36