Not applicableStudy completedNCT05572125What this trial is testingIron Therapy in Erythropoietic ProtoporphyriaWho this might be right forErythropoietic ProtoporphyriaIron-deficiency Bispebjerg Hospital 10
Large-scale testing (Phase 3)Looking for participantsNCT06910358What this trial is testingStudy of Bitopertin in Participants With EPP or XLP (APOLLO)Who this might be right forErythropoietic Protoporphyria (EPP)X-Linked Protoporphyria (XLP) Disc Medicine, Inc 150
Not applicableStudy completedNCT01688895What this trial is testingErythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial ImpactWho this might be right forErythropoietic ProtoporphyriaEPPX-Linked Protoporphyria+5 more Icahn School of Medicine at Mount Sinai 150
Not applicableLooking for participantsNCT04883905What this trial is testingELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)Who this might be right forAcute Hepatic Porphyria Alnylam Pharmaceuticals 150
Not applicableUnknownNCT00004331What this trial is testingStudies in Porphyria I: Characterization of Enzyme DefectsWho this might be right forPorphyria National Center for Research Resources (NCRR) 25
Not applicableEnded earlyNCT03547297What this trial is testingINSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHPWho this might be right forAcute Hepatic PorphyriaHepatic PorphyriasAcute Intermittent Porphyria (AIP)+4 more Alnylam Pharmaceuticals 212
Not applicableActive Not RecruitingNCT05344599What this trial is testingEvaluating the Prevalence of Acute Hepatic Porphyria in Postural Tachycardia SyndromeWho this might be right forPostural Orthostatic Tachycardia SyndromeAcute Hepatic Porphyria Vanderbilt University Medical Center 70
Testing effectiveness (Phase 2)Study completedNCT06388642What this trial is testingPharmacokinetics of Afamelanotide in EPP PatientsWho this might be right forErythropoietic Protoporphyria Clinuvel Europe Limited 28
Testing effectiveness (Phase 2)Study completedNCT02949830What this trial is testingEvaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)Who this might be right forAcute Intermittent Porphyria Alnylam Pharmaceuticals 16
Early research (Phase 1)Study completedNCT00004397What this trial is testingPhase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of PorphyriaWho this might be right forPorphyria National Center for Research Resources (NCRR) 20
Not applicableStudy completedNCT03906214What this trial is testingEvidence-based Assessment of Medication Sensitivity in Acute Hepatic PorphyriaWho this might be right forPorphyrias University of South Florida 60
Large-scale testing (Phase 3)Study completedNCT03338816What this trial is testingENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)Who this might be right forAcute Hepatic PorphyriaAcute Intermittent PorphyriaPorphyria, Acute Intermittent+4 more Alnylam Pharmaceuticals 94
Not applicableApproved For MarketingNCT04056481What this trial is testingExpanded Access Protocol of Givosiran for Patients With Acute Hepatic PorphyriaWho this might be right forAcute Hepatic Porphyria Alnylam Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT02180412What this trial is testingControlled Trial of Panhematin in Treatment of Acute Attacks of PorphyriaWho this might be right forAcute Porphyrias The University of Texas Medical Branch, Galveston 20
Not applicableStudy completedNCT00004831What this trial is testingStudy of Cysteine Hydrochloride for Erythropoietic ProtoporphyriaWho this might be right forErythropoietic Protoporphyria FDA Office of Orphan Products Development 20
Testing effectiveness (Phase 2)Study completedNCT00004396What this trial is testingStudies in Porphyria III: Heme and Tin Mesoporphyrin in Acute PorphyriasWho this might be right forPorphyria National Center for Research Resources (NCRR) 32
Testing effectiveness (Phase 2)Ended earlyNCT02922413What this trial is testingPanhematin for Prevention of Acute Attacks of PorphyriaWho this might be right forAcute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria The University of Texas Medical Branch, Galveston 13
Testing effectiveness (Phase 2)Study completedNCT05020184What this trial is testingEffect of Oral Cimetidine in the ProtoporphyriasWho this might be right forErythropoietic ProtoporphyriaX-linked Protoporphyria Amy K. Dickey, M.D. 26
Testing effectiveness (Phase 2)Study completedNCT00004789What this trial is testingPhase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute PorphyriaWho this might be right forPorphyria National Center for Research Resources (NCRR) 59
Large-scale testing (Phase 3)Study completedNCT00599326What this trial is testingPilot Trial of Deferasirox in the Treatment of Porphyria Cutanea TardaWho this might be right forPorphyria Cutanea Tarda University of Texas Southwestern Medical Center 10