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Results for “Primary Lateral Sclerosis, Adult, 1”

13 trials

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Showing 13 of 13 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06100276
What this trial is testing

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
UniQure Biopharma B.V. 20
Early research (Phase 1)Study completedNCT05797701
What this trial is testing

A Study in Healthy Adult Male & Female Participants to Assess the Amount of the Study Medicine (SAR443820) Absorbed by the Body, When Given Orally in Fasted Condition as a Tablet Versus as a Capsule (Part 1) and When Given Orally as a Tablet in Fasted Condition Versus as a Tablet After Food (Part 2)

Who this might be right for
Amyotrophic Lateral Sclerosis (Healthy Volunteers)
Sanofi 18
Early research (Phase 1)Looking for participantsNCT05995782
What this trial is testing

A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418

Who this might be right for
Parkinson Disease PsychosisAmyotrophic Lateral Sclerosis (ALS)
1ST Biotherapeutics, Inc. 64
Early research (Phase 1)Study completedNCT03945279
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB100 Administered Orally to Adults With Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
Biogen 49
Early research (Phase 1)Looking for participantsNCT07221240
What this trial is testing

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
PRG Science & Technology Co., Ltd. 48
Early research (Phase 1)Looking for participantsNCT06453668
What this trial is testing

TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients

Who this might be right for
ALS
ITB-Med LLC 48
Not applicableTemporarily pausedNCT04031469
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Who this might be right for
Gut MicrobiomeGastrointestinal MicrobiomeAutism+77 more
ProgenaBiome 1,000
Early research (Phase 1)WithdrawnNCT05949294
What this trial is testing

Study of AROSOD-1 in Adult Participants With Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Arrowhead Pharmaceuticals
Early research (Phase 1)Study completedNCT05882695
What this trial is testing

Study of SPG302 in Healthy Volunteers and ALS Participants

Who this might be right for
Amyotrophic Lateral Sclerosis
Spinogenix 88
Not applicableNo Longer AvailableNCT04825613
What this trial is testing

"Individual Patient Expanded Access IND to Treat Primary Lateral Sclerosis"

Who this might be right for
Primary Lateral Sclerosis, Adult, 1
Hope Biosciences Research Foundation
Early research (Phase 1)Looking for participantsNCT06665165
What this trial is testing

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

Who this might be right for
ALS
Amylyx Pharmaceuticals Inc. 48
Large-scale testing (Phase 3)Study completedNCT02623699
What this trial is testing

An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 (Tofersen) in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Biogen 176
Early research (Phase 1)Study completedNCT05797753
What this trial is testing

Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B)

Who this might be right for
Amyotrophic Lateral SclerosisHealthy Volunteer
Sanofi 16