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Results for “Primary Mediastinal B-cell Lymphoma”

159 trials

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Showing 20 of 159 results

Testing effectiveness (Phase 2)Enrolling By InvitationNCT06871007
What this trial is testing

Nivolumab and DA-EPOCH-R in Pediatric Primary Mediastinal (Thymic) Large B-cell Lymphoma

Who this might be right for
Primary Mediastinal (Thymic) Large B-cell LymphomaChildrenNivolumab
St. Petersburg State Pavlov Medical University 22
Early research (Phase 1)Ended earlyNCT03103971
What this trial is testing

HuJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

Who this might be right for
Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent B-Cell Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell Lymphoma+14 more
Fred Hutchinson Cancer Center 55
Early research (Phase 1)Active Not RecruitingNCT04049513
What this trial is testing

ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)

Who this might be right for
Lymphomas Non-Hodgkin's B-CellDiffuse Large B-cell Lymphoma (DLBCL)Primary Mediastinal B-cell Lymphoma (PMBCL)+3 more
Malaghan Institute of Medical Research 30
Testing effectiveness (Phase 2)Looking for participantsNCT07788118
What this trial is testing

A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory Large B-cell Lymphoma (LBCL)Diffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+2 more
Second Affiliated Hospital, Zhejiang University, School of Medicine 70
Testing effectiveness (Phase 2)Study completedNCT04323657
What this trial is testing

TC-110 T Cells in Adults With Relapsed or Refractory Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

Who this might be right for
Non Hodgkin LymphomaAcute Lymphoblastic LeukemiaDiffuse Large B Cell Lymphoma+3 more
TCR2 Therapeutics 6
Not applicableActive Not RecruitingNCT06024694
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma With CNS Involvement

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
IRCCS San Raffaele 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT03038672
What this trial is testing

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

Who this might be right for
ALK-Positive Large B-Cell LymphomaDiffuse Large B-Cell Lymphoma Activated B-Cell TypeDiffuse Large B-Cell Lymphoma Associated With Chronic Inflammation+32 more
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)Temporarily pausedNCT07098364
What this trial is testing

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent Grade 3b Follicular Lymphoma+9 more
Fred Hutchinson Cancer Center 33
Testing effectiveness (Phase 2)UnknownNCT04600947
What this trial is testing

Study of LP002 for the Treatment of Patients With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma

Who this might be right for
Primary Mediastinal Large B-Cell Lymphoma (PMBCL)
Taizhou HoudeAoke Biomedical Co., Ltd. 69
Not applicableLooking for participantsNCT04824950
What this trial is testing

Circulating Tumor DNA in Primary Mediastinal Large B-cell Lymphoma (PMBL)

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma
Centre Henri Becquerel 87
Testing effectiveness (Phase 2)Study completedNCT03035331
What this trial is testing

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

Who this might be right for
Aggressive Non-Hodgkin LymphomaIndolent Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell Lymphoma+7 more
Mayo Clinic 11
Testing effectiveness (Phase 2)Looking for participantsNCT06500273
What this trial is testing

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Who this might be right for
Large B-cell Lymphoma
Allogene Therapeutics 250
Testing effectiveness (Phase 2)Study completedNCT03210662
What this trial is testing

Pembrolizumab and External Beam Radiation Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Who this might be right for
Primary Mediastinal (Thymic) Large B-Cell LymphomaRecurrent Aggressive Non-Hodgkin LymphomaRecurrent Mature T- Cell and NK-Cell Non-Hodgkin Lymphoma+8 more
M.D. Anderson Cancer Center 17
Testing effectiveness (Phase 2)Looking for participantsNCT07097363
What this trial is testing

Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma

Who this might be right for
B-Cell Non-Hodgkin LymphomaBurkitt LymphomaDiffuse Large B-Cell Lymphoma, Not Otherwise Specified+6 more
University of Washington 18
Not applicableStudy completedNCT05162170
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 633
Early research (Phase 1)Active Not RecruitingNCT06014762
What this trial is testing

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Who this might be right for
Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
Poseida Therapeutics, Inc. 120
Early research (Phase 1)Study completedNCT03028103
What this trial is testing

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Who this might be right for
Diffuse Large B Cell LymphomaPrimary Mediastinal LymphomaMantle Cell Lymphoma+2 more
Epizyme, Inc. 32
Testing effectiveness (Phase 2)Study completedNCT01859819
What this trial is testing

Treatment for Advanced B-Cell Lymphoma

Who this might be right for
Diffuse Large Cell LymphomaBurkitt's LymphomaHigh Grade B-cell Lymphoma
New York Medical College 45
Not applicableNot Yet RecruitingNCT07463781
What this trial is testing

Neurocognitive Assessment in Adults Undergoing CD19 Targeted CAR-T Cell Therapy

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)High Grade B Cell LymphomaPrimary Mediastinal B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 100
Testing effectiveness (Phase 2)Looking for participantsNCT04186520
What this trial is testing

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Who this might be right for
Non Hodgkin Lymphoma (NHL)Mantle Cell Lymphoma (MCL)Chronic Lymphocytic Leukemia (CLL)+5 more
Medical College of Wisconsin 100
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