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Results for “Primary Mediastinal Large B-Cell Lymphoma (PMBCL)”

38 trials

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Showing 20 of 38 results

Early research (Phase 1)Active Not RecruitingNCT04049513
What this trial is testing

ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)

Who this might be right for
Lymphomas Non-Hodgkin's B-CellDiffuse Large B-cell Lymphoma (DLBCL)Primary Mediastinal B-cell Lymphoma (PMBCL)+3 more
Malaghan Institute of Medical Research 30
Testing effectiveness (Phase 2)Looking for participantsNCT07788118
What this trial is testing

A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory Large B-cell Lymphoma (LBCL)Diffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+2 more
Second Affiliated Hospital, Zhejiang University, School of Medicine 70
Not applicableActive Not RecruitingNCT06024694
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma With CNS Involvement

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
IRCCS San Raffaele 45
Testing effectiveness (Phase 2)UnknownNCT04600947
What this trial is testing

Study of LP002 for the Treatment of Patients With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma

Who this might be right for
Primary Mediastinal Large B-Cell Lymphoma (PMBCL)
Taizhou HoudeAoke Biomedical Co., Ltd. 69
Testing effectiveness (Phase 2)Looking for participantsNCT06500273
What this trial is testing

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Who this might be right for
Large B-cell Lymphoma
Allogene Therapeutics 250
Not applicableStudy completedNCT05162170
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 633
Early research (Phase 1)Active Not RecruitingNCT06014762
What this trial is testing

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Who this might be right for
Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
Poseida Therapeutics, Inc. 120
Not applicableNot Yet RecruitingNCT07463781
What this trial is testing

Neurocognitive Assessment in Adults Undergoing CD19 Targeted CAR-T Cell Therapy

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)High Grade B Cell LymphomaPrimary Mediastinal B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 100
Testing effectiveness (Phase 2)Looking for participantsNCT04186520
What this trial is testing

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Who this might be right for
Non Hodgkin Lymphoma (NHL)Mantle Cell Lymphoma (MCL)Chronic Lymphocytic Leukemia (CLL)+5 more
Medical College of Wisconsin 100
Not applicableStudy completedNCT05130489
What this trial is testing

CAR T Cell Therapy Related Cardiovascular Outcomes

Who this might be right for
Cardiovascular DiseasesB-cell Acute Lymphoblastic LeukemiaB-cell Lymphoma Refractory+5 more
University College London Hospitals 150
Early research (Phase 1)Looking for participantsNCT06464861
What this trial is testing

Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma

Who this might be right for
Primary Mediastinal B-cell Lymphoma (PMBCL)Mantle Cell Lymphoma (MCL)Diffuse Large B Cell Lymphoma( DLBCL)
Second Affiliated Hospital, Zhejiang University, School of Medicine 52
Testing effectiveness (Phase 2)Active Not RecruitingNCT04745559
What this trial is testing

Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy

Who this might be right for
Diffuse Large-Cell LymphomaPrimary Mediastinal Large B-Cell Lymphoma (PMBCL)Transformed Follicular Lymphoma (TFL)+2 more
H. Lee Moffitt Cancer Center and Research Institute 26
Not applicableLooking for participantsNCT07750886
What this trial is testing

Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL)

Who this might be right for
Non-Hodgkin LymphomaT-Cell LymphomaDiffuse Large B-Cell Lymphoma+7 more
Natera, Inc. 200
Testing effectiveness (Phase 2)Looking for participantsNCT05826535
What this trial is testing

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

Who this might be right for
Relapsed Non-Hodgkin LymphomaRefractory Non-Hodgkin LymphomaNon-Hodgkin Lymphoma+1 more
Lyell Immunopharma, Inc. 270
Not applicableLooking for participantsNCT05366569
What this trial is testing

Bio-CAR-T BS Study

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)Acute Lymphoblastic Leukemia (ALL)
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 45
Testing effectiveness (Phase 2)Looking for participantsNCT04792489
What this trial is testing

DALY II USA/ MB-CART2019.1 for DLBCL

Who this might be right for
Refractory Diffuse Large B Cell Lymphoma (DLBCL)Relapsed Diffuse Large B Cell LymphomaHigh Grade B-cell Lymphoma (HGBCL)+6 more
Miltenyi Biomedicine GmbH 315
Testing effectiveness (Phase 2)Looking for participantsNCT06486051
What this trial is testing

Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Who this might be right for
Large B-cell LymphomaDiffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+1 more
Malaghan Institute of Medical Research 60
Testing effectiveness (Phase 2)Study completedNCT04875195
What this trial is testing

Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)

Who this might be right for
Hodgkin's LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)
Merck Sharp & Dohme LLC 66
Early research (Phase 1)Looking for participantsNCT06026319
What this trial is testing

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

Who this might be right for
Non-hodgkin LymphomaRelapsed Non-Hodgkin LymphomaRefractory Non-Hodgkin Lymphoma+7 more
Marcela V. Maus, M.D.,Ph.D. 24
Testing effectiveness (Phase 2)Looking for participantsNCT07473167
What this trial is testing

Study of Safety and Efficacy of TC011 in the Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma Patients

Who this might be right for
Relapsed Large B-cell LymphomaRefractory Large B-cell LymphomaDiffuse Large B-cell Lymphoma (DLBCL)+3 more
TICAROS Co., Ltd. 98
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