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Results for “Primary Mediastinal Large B-cell Lymphoma (PMBCL)”

33 trials

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Showing 20 of 33 results

Early research (Phase 1)Active Not RecruitingNCT04526834
What this trial is testing

Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma

Who this might be right for
Anaplastic Large Cell LymphomaPeripheral T Cell LymphomaExtranodal NK/T-cell Lymphoma+2 more
Tessa Therapeutics 21
Early research (Phase 1)Enrolling By InvitationNCT07168486
What this trial is testing

CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas

Who this might be right for
B-Cell LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
University of Maryland, Baltimore 15
Testing effectiveness (Phase 2)Looking for participantsNCT05826535
What this trial is testing

Study of LYL314 in Aggressive Large B-Cell Lymphoma

Who this might be right for
Relapsed Non-Hodgkin LymphomaRefractory Non-Hodgkin LymphomaNon-Hodgkin Lymphoma+1 more
Lyell Immunopharma, Inc. 270
Early research (Phase 1)Looking for participantsNCT06026319
What this trial is testing

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

Who this might be right for
Non-hodgkin LymphomaRelapsed Non-Hodgkin LymphomaRefractory Non-Hodgkin Lymphoma+7 more
Marcela V. Maus, M.D.,Ph.D. 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03625037
What this trial is testing

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

Who this might be right for
DLBCLHigh-grade B-cell Lymphoma (HGBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+6 more
Genmab 666
Testing effectiveness (Phase 2)Study completedNCT03610724
What this trial is testing

Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients

Who this might be right for
Non-Hodgkin Lymphoma
Novartis Pharmaceuticals 34
Not applicableActive Not RecruitingNCT06024694
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma With CNS Involvement

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
IRCCS San Raffaele 45
Not applicableStudy completedNCT05130489
What this trial is testing

CAR T Cell Therapy Related Cardiovascular Outcomes

Who this might be right for
Cardiovascular DiseasesB-cell Acute Lymphoblastic LeukemiaB-cell Lymphoma Refractory+5 more
University College London Hospitals 150
Not applicableApproved For MarketingNCT05733650
What this trial is testing

Expanded Access Program for Epcoritamab

Who this might be right for
Large B-cell LymphomaDiffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+2 more
Genmab
Early research (Phase 1)Looking for participantsNCT06014762
What this trial is testing

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Who this might be right for
Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
Poseida Therapeutics, Inc. 120
Testing effectiveness (Phase 2)UnknownNCT04600947
What this trial is testing

Study of LP002 for the Treatment of Patients With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma

Who this might be right for
Primary Mediastinal Large B-Cell Lymphoma (PMBCL)
Taizhou HoudeAoke Biomedical Co., Ltd. 69
Testing effectiveness (Phase 2)Looking for participantsNCT06500273
What this trial is testing

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Who this might be right for
Large B-cell Lymphoma
Allogene Therapeutics 250
Testing effectiveness (Phase 2)Active Not RecruitingNCT05583149
What this trial is testing

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Who this might be right for
Refractory Aggressive B-cell LymphomasRefractory B-Cell Non-Hodgkin LymphomaAggressive B-cell NHL+10 more
Patrick C. Johnson, MD 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06412068
What this trial is testing

A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment

Who this might be right for
Primary Mediastinal Large B Cell Lymphoma
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Looking for participantsNCT04836507
What this trial is testing

Study of Efficacy and Safety of CRC01 in Adult Large B-cell Lymphoma Patients

Who this might be right for
Relapsed Large B-cell LymphomaRefractory Large B-cell LymphomaDiffuse Large B-cell Lymphoma (DLBCL)+3 more
Curocell Inc. 91
Not applicableLooking for participantsNCT05934084
What this trial is testing

Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors

Who this might be right for
Classical Hodgkin LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 552
Early research (Phase 1)Looking for participantsNCT06208735
What this trial is testing

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

Who this might be right for
B-Cell LeukemiaNon-Hodgkin's LymphomaB-cell Acute Lymphoblastic Leukemia+5 more
British Columbia Cancer Agency 24
Testing effectiveness (Phase 2)Looking for participantsNCT04186520
What this trial is testing

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Who this might be right for
Non Hodgkin Lymphoma (NHL)Mantle Cell Lymphoma (MCL)Chronic Lymphocytic Leukemia (CLL)+5 more
Medical College of Wisconsin 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04745559
What this trial is testing

Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy

Who this might be right for
Diffuse Large-Cell LymphomaPrimary Mediastinal Large B-Cell Lymphoma (PMBCL)Transformed Follicular Lymphoma (TFL)+2 more
H. Lee Moffitt Cancer Center and Research Institute 26
Testing effectiveness (Phase 2)Looking for participantsNCT06533579
What this trial is testing

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaLarge B-cell LymphomaChronic Lymphocytic Leukemia+10 more
Vironexis Biotherapeutics Inc. 32
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