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Results for “Primary Mediastinal Large B-cell Lymphoma (PMBCL)”

38 trials

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Showing 20 of 38 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03625037
What this trial is testing

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

Who this might be right for
DLBCLHigh-grade B-cell Lymphoma (HGBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+6 more
Genmab 666
Testing effectiveness (Phase 2)UnknownNCT04705129
What this trial is testing

Zanubrutinib Combined With Tislelizumab in the Treatment of r/r PMBCL and EBV+ DLBCL

Who this might be right for
Primary Mediastinal Large B Cell LymphomaEBV-Positive DLBCL, Nos
Ruijin Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT04186520
What this trial is testing

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Who this might be right for
Non Hodgkin Lymphoma (NHL)Mantle Cell Lymphoma (MCL)Chronic Lymphocytic Leukemia (CLL)+5 more
Medical College of Wisconsin 100
Testing effectiveness (Phase 2)Looking for participantsNCT06533579
What this trial is testing

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaLarge B-cell LymphomaChronic Lymphocytic Leukemia+10 more
Vironexis Biotherapeutics Inc. 32
Early research (Phase 1)Active Not RecruitingNCT06014762
What this trial is testing

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Who this might be right for
Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
Poseida Therapeutics, Inc. 120
Testing effectiveness (Phase 2)Looking for participantsNCT06486051
What this trial is testing

Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Who this might be right for
Large B-cell LymphomaDiffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+1 more
Malaghan Institute of Medical Research 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05583149
What this trial is testing

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Who this might be right for
Refractory Aggressive B-cell LymphomasRefractory B-Cell Non-Hodgkin LymphomaAggressive B-cell NHL+10 more
Patrick C. Johnson, MD 28
Not applicableActive Not RecruitingNCT06024694
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma With CNS Involvement

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
IRCCS San Raffaele 45
Testing effectiveness (Phase 2)UnknownNCT06412068
What this trial is testing

A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment

Who this might be right for
Primary Mediastinal Large B Cell Lymphoma
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Looking for participantsNCT07788118
What this trial is testing

A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory Large B-cell Lymphoma (LBCL)Diffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+2 more
Second Affiliated Hospital, Zhejiang University, School of Medicine 70
Early research (Phase 1)Looking for participantsNCT06544265
What this trial is testing

SynKIR-310 for Relapsed/Refractory B-NHL

Who this might be right for
B Cell LymphomaNHL, AdultMantle Cell Lymphoma+23 more
Verismo Therapeutics 36
Testing effectiveness (Phase 2)Looking for participantsNCT05934448
What this trial is testing

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)Primary Mediastinal Large B Cell LymphomaPrimary Mediastinal Large B-Cell Lymphoma Refractory+3 more
Jennifer Crombie, MD 35
Not applicableLooking for participantsNCT05934084
What this trial is testing

Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors

Who this might be right for
Classical Hodgkin LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 552
Testing effectiveness (Phase 2)Study completedNCT03610724
What this trial is testing

Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients

Who this might be right for
Non-Hodgkin Lymphoma
Novartis Pharmaceuticals 34
Not applicableNot Yet RecruitingNCT07463781
What this trial is testing

Neurocognitive Assessment in Adults Undergoing CD19 Targeted CAR-T Cell Therapy

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)High Grade B Cell LymphomaPrimary Mediastinal B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 100
Not applicableStudy completedNCT05162170
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 633
Testing effectiveness (Phase 2)UnknownNCT04600947
What this trial is testing

Study of LP002 for the Treatment of Patients With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma

Who this might be right for
Primary Mediastinal Large B-Cell Lymphoma (PMBCL)
Taizhou HoudeAoke Biomedical Co., Ltd. 69
Not applicableLooking for participantsNCT06339255
What this trial is testing

Italian Observational Study on CAR-T Therapy for Lymphoma

Who this might be right for
Diffuse Low Grade B-Cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)Mantle Cell Lymphoma+1 more
Paolo Corradini 5,300
Early research (Phase 1)Ended earlyNCT05169489
What this trial is testing

BbT369 in Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma (NHL)

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)
Regeneron Pharmaceuticals 15
Early research (Phase 1)Enrolling By InvitationNCT07168486
What this trial is testing

CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas

Who this might be right for
B-Cell LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
University of Maryland, Baltimore 15
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