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Results for “Primary Progressive Multiple Sclerosis”

112 trials

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Showing 20 of 112 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05893225
What this trial is testing

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple SclerosisSecondary-progressive Multiple Sclerosis
University Hospital, Antwerp 120
Not applicableTemporarily pausedNCT04031469
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Who this might be right for
Gut MicrobiomeGastrointestinal MicrobiomeAutism+77 more
ProgenaBiome 1,000
Not applicableStudy completedNCT02305264
What this trial is testing

Imaging of Intracerebral Inflammation in MS

Who this might be right for
Multiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Secondary ProgressiveMultiple Sclerosis, Primary Progressive
Assistance Publique - Hôpitaux de Paris 61
Testing effectiveness (Phase 2)Study completedNCT03993171
What this trial is testing

31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.

Who this might be right for
Multiple Sclerosis
Clene Nanomedicine 33
Large-scale testing (Phase 3)UnknownNCT03691077
What this trial is testing

Effect of Ocrelizumab on Brain Innate Immune Microglial Cells Activation in MS Using PET-MRI With 18F-DPA714

Who this might be right for
Multiple SclerosisRelapsePrimary Progressive Multiple Sclerosis
Assistance Publique - Hôpitaux de Paris 51
Large-scale testing (Phase 3)Study completedNCT00087529
What this trial is testing

Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Genentech, Inc. 439
Not applicableUnknownNCT05229861
What this trial is testing

The Influence of HIIT Versus MCT on Cardiorespiratory Fitness in PPMS

Who this might be right for
Primary Progressive Multiple SclerosisExerciseCardiorespiratory Fitness
Klinik Valens 61
Testing effectiveness (Phase 2)Study completedNCT02913157
What this trial is testing

Hydroxychloroquine in Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary Progressive
University of Calgary 35
Early research (Phase 1)UnknownNCT00220493
What this trial is testing

Evaluation of Efficiency of Ritalin in Multiple Sclerosis (MS) Patients

Who this might be right for
Relapsing Remitting Multiple SclerosisMultiple Sclerosis, Chronic Progressive
Sheba Medical Center 80
Early research (Phase 1)Looking for participantsNCT03783416
What this trial is testing

SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis

Who this might be right for
Relapsing Remitting Multiple SclerosisPrimary Progressive Multiple SclerosisSecondary Progressive Multiple Sclerosis
Queen Mary University of London 72
Not applicableActive Not RecruitingNCT03593590
What this trial is testing

Non-interventional Study of Ocrelizumab in Participants With Relapsing or Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Hoffmann-La Roche 1,710
Not applicableStudy completedNCT04550650
What this trial is testing

Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients

Who this might be right for
Multiple Sclerosis, Chronic ProgressiveMultiple Sclerosis, Primary Progressive
Somogy Megyei Kaposi Mór Teaching Hospital 4
Post-approval studies (Phase 4)Ended earlyNCT01411514
What this trial is testing

Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Claudio Gobbi 27
Testing effectiveness (Phase 2)UnknownNCT01144117
What this trial is testing

The Effects of Erythropoietin on Clinical Disability and Brain Pathology in Patients With Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (Primary or Secondary Progressive Phase).
Rigshospitalet, Denmark 56
Not applicableNo Longer AvailableNCT02807285
What this trial is testing

Expanded Access Program for Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Genentech, Inc.
Not applicableStudy completedNCT06436131
What this trial is testing

The Effects of In-phase Bilateral Exercise in People with Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary ProgressiveMultiple Sclerosis, Secondary Progressive
Cyprus University of Technology 20
Not applicableStudy completedNCT04120675
What this trial is testing

Efficacy of Early Harvest Olive Oil in Cognition of Primary (PPMS) or Secondary (SPMS) Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
Aristotle University Of Thessaloniki 30
Not applicableLooking for participantsNCT06526364
What this trial is testing

Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)

Who this might be right for
Multiple SclerosisMultiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Primary Progressive+1 more
University Hospital, Basel, Switzerland 100
Testing effectiveness (Phase 2)UnknownNCT01466114
What this trial is testing

Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

Who this might be right for
Relapsing-remitting Multiple SclerosisSecondary-progressive Multiple SclerosisPrimary-progressive Multiple Sclerosis
University of California, Los Angeles 64
Not applicableLooking for participantsNCT06596746
What this trial is testing

Neurodegenerative Diseases Progression Markers (MARKERS-NDD)

Who this might be right for
Neurodegenerative DiseasesParkinson DiseaseSynucleinopathies+15 more
Casa di Cura San Raffaele Cassino 600
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