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Results for “Primary T-cell Immunodeficiency Disorders”

51 trials

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Showing 20 of 51 results

Testing effectiveness (Phase 2)Looking for participantsNCT02579967
What this trial is testing

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Who this might be right for
Primary T-cell Immunodeficiency DisordersCommon Variable ImmunodeficiencyImmune System Diseases+2 more
National Cancer Institute (NCI) 354
Not applicableUnknownNCT04724642
What this trial is testing

COVID-19 Vaccine in Patients After Allogeneic HCT, CAR-T Therapy and With Primary Immune Deficiency

Who this might be right for
Allogenic Hematopoietic Cell TransplantCAR-T TherapyPrimary Immunodeficiency
Tel-Aviv Sourasky Medical Center 110
Testing effectiveness (Phase 2)Active Not RecruitingNCT03663933
What this trial is testing

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Who this might be right for
Lymphoproliferative DisordersAutoimmune LymphoproliferativePrimary T-cell Immunodeficiency Disorders+2 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Testing effectiveness (Phase 2)Study completedNCT00576407
What this trial is testing

Thymus Transplantation in DiGeorge Syndrome #668

Who this might be right for
DiGeorge SyndromeComplete Typical DiGeorge Anomaly
Sumitomo Pharma Switzerland GmbH 26
Early research (Phase 1)Study completedNCT02510404
What this trial is testing

Multivirus-specific Cytotoxic T Lymphocytes (mCTL)

Who this might be right for
Refractory Viral Infections
Catherine Bollard 1
Testing effectiveness (Phase 2)Looking for participantsNCT04414046
What this trial is testing

TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children

Who this might be right for
Primary Immune Deficiency DisordersMetabolic Disease
Johns Hopkins All Children's Hospital 17
Testing effectiveness (Phase 2)Active Not RecruitingNCT03301168
What this trial is testing

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+6 more
Bellicum Pharmaceuticals 120
Early research (Phase 1)UnknownNCT03836690
What this trial is testing

Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation

Who this might be right for
LymphomaLeukemiaMyeloma+4 more
University College, London 18
Not applicableLooking for participantsNCT00246857
What this trial is testing

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

Who this might be right for
Primary Immune Deficiency
National Institute of Allergy and Infectious Diseases (NIAID) 5,000
Post-approval studies (Phase 4)Ended earlyNCT00781287
What this trial is testing

Raltegravir (Isentress/MK-0518) and HIV-1 Infected CD4 Cells During Acute/Early HIV-1

Who this might be right for
Human Immunodeficiency Virus
University of Washington 10
Testing effectiveness (Phase 2)Ended earlyNCT02127892
What this trial is testing

SCID Bu/Flu/ATG Study With T Cell Depletion

Who this might be right for
Severe Combined Immunodeficiency
Neena Kapoor, M.D. 9
Early research (Phase 1)Study completedNCT00028236
What this trial is testing

Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)

Who this might be right for
Severe Combined Immunodeficiency
National Institute of Allergy and Infectious Diseases (NIAID) 3
Testing effectiveness (Phase 2)Ended earlyNCT03075553
What this trial is testing

Nivolumab in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma

Who this might be right for
Blastic Plasmacytoid Dendritic Cell NeoplasmHepatosplenic T-Cell LymphomaHTLV-1 Infection+14 more
Mayo Clinic 12
Not applicableEnded earlyNCT02246491
What this trial is testing

Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia

Who this might be right for
Ataxia-Telangiectasia (A-T)
Johns Hopkins University 6
Not applicableStudy completedNCT02590328
What this trial is testing

Neonatal Screening of Severe Combined Immunodeficiencies

Who this might be right for
Severe Combined ImmunodeficiencyNeonatal Screening
Children's Hospital of Fudan University 180,000
Testing effectiveness (Phase 2)Study completedNCT00228852
What this trial is testing

IMM 0212: Busulfan With Fludarabine and Antithymocyte Globulin as Preparative Therapy for Hematopoietic Stem Cell Transplant for the Treatment of Severe Congenital T-Cell Immunodeficiency

Who this might be right for
T-Cell Immune Deficiency DiseasesSevere Combined Immunodeficiency
Emory University
Testing effectiveness (Phase 2)Looking for participantsNCT04554914
What this trial is testing

Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases

Who this might be right for
Epstein-Barr Virus (EBV)-Associated DiseasesEBV+ Lymphoproliferative Disease With Primary Immunodeficiency (EBV+ PID LPD)EBV+ Lymphoproliferative Disease With Acquired (Non-congenital) Immunodeficiency (EBV+ AID LPD)+8 more
Pierre Fabre Medicament
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
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