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Results for “Primary T-cell Immunodeficiency Disorders”

52 trials

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Showing 20 of 52 results

Not applicableStudy completedNCT05784415
What this trial is testing

Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell

Who this might be right for
LeukemiaLeukemia, LymphoblasticLymphoma, Large B-Cell, Diffuse+7 more
AIDS Malignancy Consortium 30
Testing effectiveness (Phase 2)Looking for participantsNCT04197596
What this trial is testing

Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

Who this might be right for
Viral InfectionPrimary Immune Deficiency Disorder
New York Medical College 40
Not applicableNo Longer AvailableNCT02915406
What this trial is testing

CliniMACs HUD for T Cell Depletion

Who this might be right for
x Linked Combined Immunodeficiency
University of Miami
Early research (Phase 1)Study completedNCT00008450
What this trial is testing

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Who this might be right for
Adenosine Deaminase DeficiencyAutosomal Recessive DisorderImmune System Disorder+4 more
Fred Hutchinson Cancer Center 6
Not applicableStudy completedNCT02244450
What this trial is testing

Generalized Neonatal Screening of Severe Combined Immunodeficiencies

Who this might be right for
Severe Combined Immunodeficiency, Atypical
Nantes University Hospital 190,539
Not applicableStudy completedNCT00112593
What this trial is testing

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in Remission+176 more
Fred Hutchinson Cancer Center 5
Not applicableStudy completedNCT00845416
What this trial is testing

Newborn Screening for Severe Combined Immunodeficiency (SCID) in a High-Risk Population

Who this might be right for
Severe Combined ImmunodeficiencyT Cell Lymphocytopenia
University of California, San Francisco 1,800
Testing effectiveness (Phase 2)Looking for participantsNCT04554914
What this trial is testing

Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases

Who this might be right for
Epstein-Barr Virus (EBV)-Associated DiseasesEBV+ Lymphoproliferative Disease With Primary Immunodeficiency (EBV+ PID LPD)EBV+ Lymphoproliferative Disease With Acquired (Non-congenital) Immunodeficiency (EBV+ AID LPD)+8 more
Pierre Fabre Medicament
Testing effectiveness (Phase 2)Ended earlyNCT03075553
What this trial is testing

Nivolumab in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma

Who this might be right for
Blastic Plasmacytoid Dendritic Cell NeoplasmHepatosplenic T-Cell LymphomaHTLV-1 Infection+14 more
Mayo Clinic 12
Testing effectiveness (Phase 2)Looking for participantsNCT03266640
What this trial is testing

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

Who this might be right for
Cytomegalovirus InfectionsPrimary Immune Deficiency Disorder
New York Medical College 20
Not applicableNot Yet RecruitingNCT07516002
What this trial is testing

Immunoglobulin Efficacy and Immune Profiling in Antibody Immunodeficiency

Who this might be right for
Primary Immunodeficiency Diseases
Peking University People's Hospital 15
Testing effectiveness (Phase 2)Ended earlyNCT02065869
What this trial is testing

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+10 more
Bellicum Pharmaceuticals 187
Testing effectiveness (Phase 2)Active Not RecruitingNCT03301168
What this trial is testing

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+6 more
Bellicum Pharmaceuticals 120
Testing effectiveness (Phase 2)Looking for participantsNCT06839456
What this trial is testing

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Who this might be right for
LeukemiaHigh Risk Acute Lymphoblastic LeukemiaHigh Risk Acute Myeloid Leukemia+11 more
Children's Hospital of Philadelphia 100
Early research (Phase 1)Study completedNCT00890747
What this trial is testing

Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAcute Undifferentiated Leukemia+82 more
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)Ended earlyNCT03733249
What this trial is testing

Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+9 more
Bellicum Pharmaceuticals 187
Large-scale testing (Phase 3)Ended earlyNCT00176826
What this trial is testing

T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+4 more
Masonic Cancer Center, University of Minnesota 22
Early research (Phase 1)Ended earlyNCT02231710
What this trial is testing

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Who this might be right for
Primary Immune Deficiency DisordersHemophagocytic LymphohistiocytosisInherited Bone Marrow Failure Syndrome+2 more
Bellicum Pharmaceuticals 1
Testing effectiveness (Phase 2)Looking for participantsNCT01306019
What this trial is testing

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

Who this might be right for
X-linked Severe Combined Immunodeficiency (XSCID)
National Institute of Allergy and Infectious Diseases (NIAID) 40
Testing effectiveness (Phase 2)Looking for participantsNCT04339777
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Who this might be right for
Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System Diseases+2 more
National Cancer Institute (NCI) 66
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