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Results for “Primary T-cell Immunodeficiency Disorders”

52 trials

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Showing 20 of 52 results

Not applicableNot Yet RecruitingNCT07516002
What this trial is testing

Immunoglobulin Efficacy and Immune Profiling in Antibody Immunodeficiency

Who this might be right for
Primary Immunodeficiency Diseases
Peking University People's Hospital 15
Testing effectiveness (Phase 2)Looking for participantsNCT04339777
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Who this might be right for
Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System Diseases+2 more
National Cancer Institute (NCI) 66
Not applicableLooking for participantsNCT00246857
What this trial is testing

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

Who this might be right for
Primary Immune Deficiency
National Institute of Allergy and Infectious Diseases (NIAID) 5,000
Testing effectiveness (Phase 2)Looking for participantsNCT03266640
What this trial is testing

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

Who this might be right for
Cytomegalovirus InfectionsPrimary Immune Deficiency Disorder
New York Medical College 20
Testing effectiveness (Phase 2)Looking for participantsNCT04414046
What this trial is testing

TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children

Who this might be right for
Primary Immune Deficiency DisordersMetabolic Disease
Johns Hopkins All Children's Hospital 17
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
Testing effectiveness (Phase 2)Looking for participantsNCT06839456
What this trial is testing

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Who this might be right for
LeukemiaHigh Risk Acute Lymphoblastic LeukemiaHigh Risk Acute Myeloid Leukemia+11 more
Children's Hospital of Philadelphia 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT02990819
What this trial is testing

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

Who this might be right for
ImmunodeficienciesImmune Dysregulation Syndromes
Children's Hospital of Philadelphia 60
Testing effectiveness (Phase 2)Study completedNCT00576407
What this trial is testing

Thymus Transplantation in DiGeorge Syndrome #668

Who this might be right for
DiGeorge SyndromeComplete Typical DiGeorge Anomaly
Sumitomo Pharma Switzerland GmbH 26
Not applicableStudy completedNCT00845416
What this trial is testing

Newborn Screening for Severe Combined Immunodeficiency (SCID) in a High-Risk Population

Who this might be right for
Severe Combined ImmunodeficiencyT Cell Lymphocytopenia
University of California, San Francisco 1,800
Testing effectiveness (Phase 2)Ended earlyNCT02065869
What this trial is testing

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+10 more
Bellicum Pharmaceuticals 187
Not applicableLooking for participantsNCT03394053
What this trial is testing

The Mechanistic Biology of Primary Immunodeficiency Disorders

Who this might be right for
Primary Immunodeficiency Disorders
National Institute of Allergy and Infectious Diseases (NIAID) 2,500
Early research (Phase 1)Looking for participantsNCT05077527
What this trial is testing

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

Who this might be right for
AIDS-Related Diffuse Large B-cell LymphomaAIDS-Related Non-Hodgkin LymphomaHIV Infection+12 more
AIDS Malignancy Consortium 20
Not applicableActive Not RecruitingNCT05321407
What this trial is testing

COVID-19 Vaccine Responses in PIDD Subjects

Who this might be right for
X-linked AgammaglobulinemiaXLAPrimary Immune Deficiency+4 more
Duke University 100
Testing effectiveness (Phase 2)Ended earlyNCT00579137
What this trial is testing

Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders

Who this might be right for
Severe Combined Immunodeficiency DiseaseSevere Primary Immunodeficiency DisorderUndefined T Cell Deficiency Disorder+1 more
Baylor College of Medicine 3
Testing effectiveness (Phase 2)Study completedNCT01529827
What this trial is testing

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+75 more
Roswell Park Cancer Institute 94
Not applicableStudy completedNCT00908544
What this trial is testing

New Era Study: Treatment With Multi Drug Class (MDC) HAART in HIV Infected Patients

Who this might be right for
HIV Infections
MUC Research GmbH 47
Testing effectiveness (Phase 2)Ended earlyNCT03333486
What this trial is testing

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Leukemia in RemissionAcute Lymphoblastic Leukemia+34 more
Roswell Park Cancer Institute 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT03663933
What this trial is testing

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Who this might be right for
Lymphoproliferative DisordersAutoimmune LymphoproliferativePrimary T-cell Immunodeficiency Disorders+2 more
National Cancer Institute (NCI) 71
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