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Results for “Primary-progressive Multiple Sclerosis”

117 trials

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Showing 20 of 117 results

Not applicableStudy completedNCT03094364
What this trial is testing

Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple SclerosisHemiparesis
University of Massachusetts, Lowell 31
Early research (Phase 1)WithdrawnNCT05029609
What this trial is testing

Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS

Who this might be right for
Primary Progressive Multiple SclerosisSecondary Progressive Multiple SclerosisMultiple Sclerosis
Tiziana Life Sciences LTD
Testing effectiveness (Phase 2)UnknownNCT01466114
What this trial is testing

Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

Who this might be right for
Relapsing-remitting Multiple SclerosisSecondary-progressive Multiple SclerosisPrimary-progressive Multiple Sclerosis
University of California, Los Angeles 64
Large-scale testing (Phase 3)Ended earlyNCT00731692
What this trial is testing

This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS.

Who this might be right for
Primary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 970
Testing effectiveness (Phase 2)Looking for participantsNCT05359653
What this trial is testing

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy

Who this might be right for
Multiple Sclerosis (MS)Multiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Primary Progressive+4 more
University of California, San Francisco 74
Early research (Phase 1)Study completedNCT04943289
What this trial is testing

Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple Sclerosis
Joanne Kurtzberg, MD 20
Large-scale testing (Phase 3)Study completedNCT00799890
What this trial is testing

Sunphenon in Progressive Forms of Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Friedemann Paul 61
Early research (Phase 1)Study completedNCT06683612
What this trial is testing

PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF

Who this might be right for
Idiopathic Pulmonary Fibrosis (IPF)Idiopathic Pulmonary FibrosisMultiple Sclerosis+6 more
Contineum Therapeutics 16
Not applicableLooking for participantsNCT07426991
What this trial is testing

Cognitive Performance, Sleep Disturbances and Fatigue in Multiple Sclerosis

Who this might be right for
Multiple SclerosisRemitting-Relapsing Multiple SclerosisPrimary Progressive Multiple Sclerosis+3 more
Heinrich-Heine University, Duesseldorf 837
Very early researchStudy completedNCT05349474
What this trial is testing

Metformin Treatment in Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple SclerosisPrimary Progressive Multiple Sclerosis
University of California, Los Angeles 23
Testing effectiveness (Phase 2)Ended earlyNCT03540485
What this trial is testing

Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary Sclerosis

Who this might be right for
Sclerosis, MultipleAutoimmune Diseases of the Nervous SystemNervous System Diseases+1 more
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 25
Not applicableActive Not RecruitingNCT03983681
What this trial is testing

Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS

Who this might be right for
Multiple Sclerosis
Kessler Foundation 120
Testing effectiveness (Phase 2)Ended earlyNCT01950234
What this trial is testing

ACTH in Progressive Forms of MS

Who this might be right for
Secondary Progressive Multiple SclerosisPrimary Progressive Multiple SclerosisProgressive Relapsing Multiple Sclerosis
University of Minnesota 59
Post-approval studies (Phase 4)Ended earlyNCT01411514
What this trial is testing

Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Claudio Gobbi 27
Not applicableLooking for participantsNCT07222618
What this trial is testing

"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS

Who this might be right for
Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remittingMultiple Sclerosis (MS) Primary Progressive+3 more
University of California, San Francisco 300
Large-scale testing (Phase 3)Active Not RecruitingNCT06372145
What this trial is testing

Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Who this might be right for
Relapsing Multiple SclerosisSecondary Progressive Multiple SclerosisProgressive Relapsing Multiple Sclerosis
Sanofi 2,500
Testing effectiveness (Phase 2)Study completedNCT01450488
What this trial is testing

Masitinib in Primary Progressive Multiple Sclerosis or Relapse-free Secondary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
AB Science 35
Large-scale testing (Phase 3)Study completedNCT02688985
What this trial is testing

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

Who this might be right for
Relapsing Multiple SclerorsisMultiple Sclerosis, Primary Progressive
Genentech, Inc. 131
Large-scale testing (Phase 3)Active Not RecruitingNCT04035005
What this trial is testing

Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary Progressive
Hoffmann-La Roche 1,013
Not applicableUnknownNCT04977622
What this trial is testing

Gray Matter Demyelination in Primary Progressive MS at 7T

Who this might be right for
Primary Progressive Multiple Sclerosis
Danish Research Centre for Magnetic Resonance 60
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