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Results for “Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04579224
What this trial is testing

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

Who this might be right for
Metastatic Bladder Urothelial CarcinomaMetastatic Urothelial CarcinomaRefractory Bladder Urothelial Carcinoma+2 more
National Cancer Institute (NCI) 184
Early research (Phase 1)Study completedNCT04551950
What this trial is testing

Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)

Who this might be right for
Cervical Cancer
EMD Serono Research & Development Institute, Inc. 25
Early research (Phase 1)Study completedNCT01295827
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001/KEYNOTE-001)

Who this might be right for
Cancer, Solid Tumor
Merck Sharp & Dohme LLC 1,260
Large-scale testing (Phase 3)Study completedNCT02395172
What this trial is testing

Avelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
EMD Serono Research & Development Institute, Inc. 792
Early research (Phase 1)Ended earlyNCT03292172
What this trial is testing

Evaluate the Safety, Pharmacokinetics and Clinical Activity of RO6870810 and Atezolizumab (PD-L1 Antibody) in Participants With Advanced Ovarian Cancer or Triple Negative Breast Cancer

Who this might be right for
Advanced Ovarian CancerTriple Negative Breast Cancer
Hoffmann-La Roche 36
Large-scale testing (Phase 3)Looking for participantsNCT05754853
What this trial is testing

MRG002 Versus Investigator's Choice of Chemotherapy in the Treatment of Patients With HER2-positive Unresectable Advanced or Metastatic Urothelial Cancer

Who this might be right for
Advanced or Metastatic Urothelium Cancer
Shanghai Miracogen Inc. 290
Not applicableLooking for participantsNCT05985330
What this trial is testing

Pilot Study of the Contribution of Fractional Exhaled Nitric Oxide as a Prognostic Marker of Response to Anti-PD-L1 Immunotherapy in Non-small Cell Lung Cancer

Who this might be right for
Metastatic Non-small Cell Lung Cancer
Centre Hospitalier Universitaire Dijon 56
Testing effectiveness (Phase 2)Study completedNCT03642067
What this trial is testing

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal AdenocarcinomasColorectal Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 59
Testing effectiveness (Phase 2)Active Not RecruitingNCT04739800
What this trial is testing

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Who this might be right for
Fallopian Tube Mucinous AdenocarcinomaOvarian Seromucinous CarcinomaPlatinum-Refractory Fallopian Tube Carcinoma+47 more
National Cancer Institute (NCI) 120
Not applicableUnknownNCT03787953
What this trial is testing

A Real World Study of Anti-PD-1/PD-L1 Antibodies for the Treatment of Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Chinese PLA General Hospital 400
Not applicableLooking for participantsNCT07696832
What this trial is testing

Efficacy and Safety of Ivonescimab Monotherapy as First-Line Treatment for PD-L1-Positive, Driver Gene-Negative, Locally Advanced or Metastatic NSCLC: A Multicenter, Prospective, Real-World Cohort Study

Who this might be right for
Patients Must Have Histologically or Cytologically Confirmed Locally Advanced or Metastatic NSCLCEGFR Mutation-negative and ALK Rearrangement-negativeEastern Cooperative Oncology Group Performance Status (ECOG PS) Score of 0 to 2+2 more
Guangdong Association of Clinical Trials
Early research (Phase 1)Ended earlyNCT02553499
What this trial is testing

Study of MK-1248 With and Without Pembrolizumab (MK-3475) for Participants With Advanced Solid Tumors (MK-1248-001)

Who this might be right for
Advanced Solid Tumor
Merck Sharp & Dohme LLC 37
Not applicableUnknownNCT03701607
What this trial is testing

Effect of Chemotherapy on PD-L1 in NSCLC

Who this might be right for
ChemotherapyImmunotherapyPD-L1
Baodong Qin 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05445843
What this trial is testing

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Who this might be right for
Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
Novartis Pharmaceuticals 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT02955290
What this trial is testing

CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaLung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell Carcinoma+13 more
Roswell Park Cancer Institute 51
Testing effectiveness (Phase 2)Study completedNCT02530489
What this trial is testing

Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast Cancer

Who this might be right for
Breast AdenocarcinomaInvasive Breast CarcinomaTriple-Negative Breast Carcinoma
M.D. Anderson Cancer Center 37
Testing effectiveness (Phase 2)Looking for participantsNCT06698250
What this trial is testing

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

Who this might be right for
Hepatocellular Carcinoma
Anwaar Saeed 40
Testing effectiveness (Phase 2)Study completedNCT02403271
What this trial is testing

A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors

Who this might be right for
Non-Small Cell Lung CancerBreast CancerPancreatic Cancer
Pharmacyclics LLC. 124
Testing effectiveness (Phase 2)Looking for participantsNCT06769152
What this trial is testing

A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Patients With Advanced Gynecological Malignant Tumors

Who this might be right for
Cervical CancerOvarian Cancer
Shanghai Henlius Biotech 190
Early research (Phase 1)Study completedNCT02720068
What this trial is testing

Study of Favezelimab (MK-4280) as Monotherapy and in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy or Lenvatinib (MK-7902) AND Favezelimab/Pembrolizumab (MK-4280A) as Monotherapy in Adults With Advanced Solid Tumors (MK-4280-001)

Who this might be right for
Neoplasms
Merck Sharp & Dohme LLC 481
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