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Results for “Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT03356860
What this trial is testing

Safety and Efficacy of Durvalumab Combined to Neoadjuvant Chemotherapy in Localized Luminal B HER2(-) and Triple Negative Breast Cancer.

Who this might be right for
Breast CancerTriple Negative Breast CancerLuminal B
Grand Hôpital de Charleroi 57
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05859217
What this trial is testing

Combining Cabozantinib and Atezolizumab for Advanced/Metastatic NSCLC (Cabatezo-1)

Who this might be right for
Lung CancerNSCLC Stage IVMetastatic NSCLC - Non-Small Cell Lung Cancer+1 more
Jun Zhang, MD, PhD 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT05604560
What this trial is testing

A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer

Who this might be right for
Pancreatic Cancer
Lei Zheng 25
Testing effectiveness (Phase 2)Study completedNCT04847050
What this trial is testing

A Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants With Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants With Solid Tumors on PD1/PDL1 Inhibitor Therapy

Who this might be right for
Solid Tumor MalignancyHematologic MalignancyLeukemia+2 more
National Cancer Institute (NCI) 19
Early research (Phase 1)Study completedNCT01375842
What this trial is testing

Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PDL1] Antibody) to Evaluate Safety, Tolerability and Pharmacokinetics in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
TumorsHematologic Malignancies
Genentech, Inc. 661
Testing effectiveness (Phase 2)Study completedNCT02431559
What this trial is testing

Phase 1/2 Study of Motolimod, Doxorubicin, and Durvalumab in Recurrent, Platinum-Resistant Ovarian Cancer

Who this might be right for
Ovarian Cancer
Ludwig Institute for Cancer Research 53
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07746388
What this trial is testing

Adaptive Chemotherapy for Pd-l1 High REsEctablE NSCLC: A Chemo-PHREE Trial

Who this might be right for
NsclcNSCLC Stage IINSCLC, Stage III+2 more
University of Maryland, Baltimore 30
Early research (Phase 1)Study completedNCT02892318
What this trial is testing

A Study Evaluating the Safety and Pharmacology of Atezolizumab Administered in Combination With Immunomodulatory Agents in Participants With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Hoffmann-La Roche 40
Testing effectiveness (Phase 2)Looking for participantsNCT07070232
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 1,438
Early research (Phase 1)Study completedNCT02027961
What this trial is testing

Phase 1 Safety and Tolerability of MEDI4736 in Combination With Dabrafenib and Trametinib or With Trametinib Alone

Who this might be right for
Melanoma
MedImmune LLC 68
Testing effectiveness (Phase 2)Looking for participantsNCT05886439
What this trial is testing

LK101 Combined With PD-1 or PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer

Who this might be right for
Lung Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 60
Testing effectiveness (Phase 2)Study completedNCT04995419
What this trial is testing

Evaluate Enfortumab Vedotin (ASG-22CE) in Chinese Participants With Locally Advanced or Metastatic Urothelial Cancer Who Previously Received Platinum-containing Chemotherapy and Programmed Cell Death Protein-1 ( PD 1) / (Programmed Death Ligand-1 (PD-L1) Inhibitor Therapy

Who this might be right for
Metastatic Urothelial Cancer
Astellas Pharma China, Inc. 40
Large-scale testing (Phase 3)Study completedNCT01905657
What this trial is testing

Study of Two Doses of Pembrolizumab (MK-3475) Versus Docetaxel in Previously Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010)

Who this might be right for
Non Small Cell Lung Cancer (NSCLC)
Merck Sharp & Dohme LLC 1,034
Testing effectiveness (Phase 2)Looking for participantsNCT06070012
What this trial is testing

Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma

Who this might be right for
Uveal Melanoma
Diwakar Davar 44
Early research (Phase 1)Looking for participantsNCT06564623
What this trial is testing

Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers (BTC)

Who this might be right for
Biliary Tract Cancers
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 25
Large-scale testing (Phase 3)Looking for participantsNCT06899126
What this trial is testing

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Daiichi Sankyo 686
Testing effectiveness (Phase 2)Looking for participantsNCT06907615
What this trial is testing

A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
Non Small Cell Lung Cancer
Shanghai Henlius Biotech 243
Testing effectiveness (Phase 2)Active Not RecruitingNCT03141684
What this trial is testing

Testing Atezolizumab Alone or Atezolizumab Plus Bevacizumab in People With Advanced Alveolar Soft Part Sarcoma

Who this might be right for
Metastatic Alveolar Soft Part SarcomaUnresectable Alveolar Soft Part Sarcoma
National Cancer Institute (NCI) 63
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07108816
What this trial is testing

A Single-center, Phase II Clinical Trial Evaluating the Efficacy of Sacituzumab Tirumotecan in Combination With Tagitanlimab as Neoadjuvant Therapy for PD-L1-positive, Resectable Stage II to IIIB Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
Resectable Stage II-IIIB NSCLC
Henan Cancer Hospital 52
Not applicableStudy completedNCT02840058
What this trial is testing

Interest of Anti-telomerase T CD4 Immune Responses for Predicting the Effectiveness of Immunotherapies Targeting PD1 / PDL1

Who this might be right for
Cancer
Centre Hospitalier Universitaire de Besancon 295
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