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Results for “Progressive Familial Intrahepatic Cholestasis”

34 trials

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Showing 20 of 34 results

Testing effectiveness (Phase 2)Study completedNCT04729751
What this trial is testing

Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS).

Who this might be right for
Progressive Familial Intrahepatic CholestasisAlagille SyndromeCholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 27
Not applicableNo Longer AvailableNCT01949766
What this trial is testing

Transition From Buphenyl to RAVICTI for the Therapy of Byler Disease

Who this might be right for
Byler Disease
University of Pittsburgh
Not applicableNo Longer AvailableNCT01784718
What this trial is testing

Buphenyl Therapy for Byler's Disease

Who this might be right for
Byler Disease
University of Pittsburgh
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Large-scale testing (Phase 3)Study completedNCT03566238
What this trial is testing

This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC Types 1 or 2

Who this might be right for
PFIC1PFIC2
Albireo 62
Post-approval studies (Phase 4)Study completedNCT04640571
What this trial is testing

Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition

Who this might be right for
Bile Salt Export Pump (BSEP) TransporterPolysorbate 80
University of Maryland, Baltimore 18
Testing effectiveness (Phase 2)Ended earlyNCT01383746
What this trial is testing

Second-line Therapy of Unresectable Cholangiocarcinoma by RADIOEMBOLIZATION

Who this might be right for
Cholestasis, Progressive Familial Intrahepatic 3
Assistance Publique - Hôpitaux de Paris 5
Not applicableLooking for participantsNCT05704517
What this trial is testing

Progressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC Registry

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Institute of Liver and Biliary Sciences, India 200
Large-scale testing (Phase 3)Study completedNCT03659916
What this trial is testing

Long Term Safety & Efficacy Study Evaluating The Effect of A4250 in Children With PFIC

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Albireo, an Ipsen Company 116
Not applicableTemporarily pausedNCT00571272
What this trial is testing

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)

Who this might be right for
Liver DiseasesAlagille SyndromeAlpha 1-Antitrypsin Deficiency
Arbor Research Collaborative for Health 1,675
Not applicableApproved For MarketingNCT04483531
What this trial is testing

Odevixibat for the Treatment of Progressive Familial Intrahepatic Cholestasis

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Albireo
Large-scale testing (Phase 3)WithdrawnNCT03353454
What this trial is testing

A Placebo-controlled Study of Maralixibat (SHP625) in Pediatric Subjects With Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc.
Not applicableEnded earlyNCT01200082
What this trial is testing

Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases

Who this might be right for
Hepatobiliary Diseases
University of Nebraska 430
Not applicableUnknownNCT04071197
What this trial is testing

Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
National Liver Institute, Egypt 20
Not applicableLooking for participantsNCT07191704
What this trial is testing

Assess the Genetic Variations in Bile Flow Disorders: Linking Progressive Familial Intrahepatic Cholestasis (PFIC)-Related Genes to Symptoms in Adults With Recurrent Cholestasis in Spain

Who this might be right for
PFIC - Progressive Familial Intrahepatic Cholestasis
Ipsen 150
Not applicableNot Yet RecruitingNCT07293897
What this trial is testing

A Database Study of Maralixibat (TAK-625) in Participants With Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Alagille Syndrome (ALGS)Progressive Familial Intrahepatic Cholestasis (PFIC)
Takeda 50
Large-scale testing (Phase 3)Study completedNCT05543187
What this trial is testing

TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Takeda 5
Early research (Phase 1)Study completedNCT02963077
What this trial is testing

A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384

Who this might be right for
Orphan Cholestatic Liver DiseasesPrimary Biliary CirrhosisProgressive Familial Intrahepatic Cholestasis+1 more
Albireo 94
Not applicableLooking for participantsNCT06778174
What this trial is testing

Prospective Analysis of the Treatment of Progressive Familial Intrahepatic Cholestasis (TreatFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
University Medical Center Groningen 200
Not applicableNot Yet RecruitingNCT06506734
What this trial is testing

Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

Who this might be right for
Dental Diseases
University Hospital, Toulouse 120
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