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Results for “Progressive Familial Intrahepatic Cholestasis”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Study completedNCT04185363
What this trial is testing

An Extension Study of Maralixibat in Patients With Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc. 84
Not applicableActive Not RecruitingNCT07497724
What this trial is testing

Odevixibat Outcomes in Patients With PFIC Versus an External Control Cohort (OvEC-PFIC)

Who this might be right for
PFIC - Progressive Familial Intrahepatic Cholestasis
Ipsen 200
Testing effectiveness (Phase 2)Study completedNCT02057718
What this trial is testing

Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 (Maralixibat) in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic Cholestasis

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc. 33
Not applicableUnknownNCT04071197
What this trial is testing

Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
National Liver Institute, Egypt 20
Not applicableUnknownNCT05704517
What this trial is testing

Progressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC Registry

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Institute of Liver and Biliary Sciences, India 200
Not applicableLooking for participantsNCT06777914
What this trial is testing

Familial Intrahepatic Cholestasis-related Genes Associated with Disease Susceptibility in Hepato-biliary Cancers

Who this might be right for
Hepatobiliary CancersProgressive Familial Intrahepatic Cholestasis (PFIC)Cholestatic Liver Disease
IRCCS Azienda Ospedaliero-Universitaria di Bologna 600
Not applicableTemporarily pausedNCT00571272
What this trial is testing

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)

Who this might be right for
Liver DiseasesAlagille SyndromeAlpha 1-Antitrypsin Deficiency
Arbor Research Collaborative for Health 1,675
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Post-approval studies (Phase 4)Looking for participantsNCT07290257
What this trial is testing

Long-Term Low-Intervention SafEty and Clinical Outcomes Clinical Study of LivmArli® in Patients With Alagille Syndrome or Progressive Familial Intrahepatic Cholestasis in the European Union (LEAP-EU)

Who this might be right for
Alagille SyndromeProgressive Familial Intrahepatic Cholestasis
Mirum Pharmaceuticals, Inc. 230
Large-scale testing (Phase 3)Study completedNCT03905330
What this trial is testing

Evaluate the Efficacy and Safety of Maralixibat in Subjects With Progressive Familial Intrahepatic Cholestasis (MARCH-PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc. 93
Early research (Phase 1)Study completedNCT03082937
What this trial is testing

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Who this might be right for
Orphan Cholestatic Liver DiseasesProgressive Familial Intrahepatic CholestasisAlagille Syndrome+1 more
Albireo 6
Not applicableNo Longer AvailableNCT02094222
What this trial is testing

Expanded Access Protocol for an Intermediate Size Population - RAVICTI for Byler Disease

Who this might be right for
Byler Disease
Robert Squires, Jr.
Not applicableLooking for participantsNCT06781242
What this trial is testing

Genotype-phenotype Relationship Between Cryptogenic Cholestasis and Familial Intrahepatic Cholestasis

Who this might be right for
Cholestatic Liver DiseaseIntrahepatic CholestasisProgressive Familial Intrahepatic Cholestasis+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 300
Not applicableEnded earlyNCT01200082
What this trial is testing

Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases

Who this might be right for
Hepatobiliary Diseases
University of Nebraska 430
Not applicableLooking for participantsNCT06193928
What this trial is testing

Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)

Who this might be right for
Alagille SyndromeProgressive Familial Intrahepatic Cholestasis
Mirum Pharmaceuticals, Inc. 70
Not applicableStudy completedNCT07191704
What this trial is testing

Assess the Genetic Variations in Bile Flow Disorders: Linking Progressive Familial Intrahepatic Cholestasis (PFIC)-Related Genes to Symptoms in Adults With Recurrent Cholestasis in Spain

Who this might be right for
PFIC - Progressive Familial Intrahepatic Cholestasis
Ipsen 150
Not applicableNo Longer AvailableNCT01949766
What this trial is testing

Transition From Buphenyl to RAVICTI for the Therapy of Byler Disease

Who this might be right for
Byler Disease
University of Pittsburgh
Large-scale testing (Phase 3)Study completedNCT05543187
What this trial is testing

TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Takeda 5
Not applicableLooking for participantsNCT07411716
What this trial is testing

Pediatric Evaluation and Registry for Liver Cholestasis in Canada

Who this might be right for
PFIC - Progressive Familial Intrahepatic CholestasisAlagille Syndrome (ALGS)Cholestasis, Intrahepatic
Children's Hospital of Eastern Ontario 220
Large-scale testing (Phase 3)Study completedNCT03566238
What this trial is testing

This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC Types 1 or 2

Who this might be right for
PFIC1PFIC2
Albireo 62
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