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Results for “Progressive Low-Grade Gliomas”

35 trials

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Showing 20 of 35 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02840409
What this trial is testing

Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

Who this might be right for
Low Grade Glioma
The Hospital for Sick Children 109
Testing effectiveness (Phase 2)Study completedNCT00615927
What this trial is testing

Phase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG)

Who this might be right for
GlioblastomaGliosarcoma
Duke University 64
Large-scale testing (Phase 3)Active Not RecruitingNCT04576117
What this trial is testing

Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Who this might be right for
Recurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more
National Cancer Institute (NCI) 300
Large-scale testing (Phase 3)Active Not RecruitingNCT00978458
What this trial is testing

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Who this might be right for
Brain and Central Nervous System TumorsNeurotoxicity
Eastern Cooperative Oncology Group 540
Not applicableLooking for participantsNCT07506239
What this trial is testing

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

Who this might be right for
Low-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco 40
Testing effectiveness (Phase 2)Study completedNCT02197637
What this trial is testing

Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma

Who this might be right for
Low-Grade Glioma
Centre Oscar Lambret 39
Early research (Phase 1)Study completedNCT00098761
What this trial is testing

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 42
Large-scale testing (Phase 3)Study completedNCT00002944
What this trial is testing

Combination Chemotherapy in Treating Children With Progressive Brain Tumors

Who this might be right for
Brain TumorsCentral Nervous System Tumors
Children's Oncology Group 428
Testing effectiveness (Phase 2)Study completedNCT00003466
What this trial is testing

Temozolomide in Treating Patients With Progressive Low-Grade Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 100
Testing effectiveness (Phase 2)Study completedNCT00002749
What this trial is testing

Carboplatin in Patients With Progressive Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 25
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Early research (Phase 1)Study completedNCT00272350
What this trial is testing

ZD6474 to Treat Advanced Brain Cancer in Patients

Who this might be right for
Recurrent High-Grade GliomasProgressive Low-Grade GliomasMalignant Gliomas
National Cancer Institute (NCI) 83
Testing effectiveness (Phase 2)Looking for participantsNCT04923126
What this trial is testing

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

Who this might be right for
Low-Grade GliomaRecurrent Low-Grade GliomaProgressive Low-Grade Glioma
St. Jude Children's Research Hospital 132
Not applicableStudy completedNCT00276640
What this trial is testing

Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas

Who this might be right for
Primary Central Nervous System Neoplasms
Societe Internationale d'Oncologie Pediatrique 3,417
Testing effectiveness (Phase 2)Active Not RecruitingNCT04201457
What this trial is testing

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Who this might be right for
Low Grade Glioma (LGG) of Brain With BRAF AberrationHigh Grade Glioma (HGG) of the Brain With BRAF AberrationLow Grade Glioma of Brain With Neurofibromatosis Type 1
Pediatric Brain Tumor Consortium 57
Testing effectiveness (Phase 2)Study completedNCT00066248
What this trial is testing

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Who this might be right for
Brain TumorCentral Nervous System TumorsCachexia+5 more
University of South Florida 70
Early research (Phase 1)Not Yet RecruitingNCT07441707
What this trial is testing

Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain Tumours

Who this might be right for
Low-grade Glioma
Ipsen 6
Not applicableStudy completedNCT00077207
What this trial is testing

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Who this might be right for
Brain TumorCentral Nervous System Tumor
Children's Oncology Group 66
Testing effectiveness (Phase 2)Study completedNCT03557359
What this trial is testing

Nivolumab for Recurrent or Progressive IDH Mutant Gliomas

Who this might be right for
Gliomas
Fabio Iwamoto, MD 35
Testing effectiveness (Phase 2)WithdrawnNCT05222165
What this trial is testing

Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations

Who this might be right for
Advanced Solid TumorCNS TumorRecurrent WHO Grade II Glioma
Helsinn Healthcare SA
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