Early research (Phase 1)Study completedNCT02423525What this trial is testingSafety Study of Afatinib for Brain CancerWho this might be right forBrain Cancer Santosh Kesari 24
Large-scale testing (Phase 3)Study completedNCT00002944What this trial is testingCombination Chemotherapy in Treating Children With Progressive Brain TumorsWho this might be right forBrain TumorsCentral Nervous System Tumors Children's Oncology Group 428
Testing effectiveness (Phase 2)Study completedNCT02197637What this trial is testingPhase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade GliomaWho this might be right forLow-Grade Glioma Centre Oscar Lambret 39
Testing effectiveness (Phase 2)Study completedNCT00066248What this trial is testingCyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer TreatmentWho this might be right forBrain TumorCentral Nervous System TumorsCachexia+5 more University of South Florida 70
Testing effectiveness (Phase 2)Looking for participantsNCT04775485What this trial is testingEvaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid TumorsWho this might be right forLow-grade GliomaAdvanced Solid Tumor Day One Biopharmaceuticals, Inc. 141
Very early researchLooking for participantsNCT06381570What this trial is testingPilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade GliomasWho this might be right forLow-grade Glioma Daniel Morgenstern 57
Testing effectiveness (Phase 2)Ended earlyNCT01338857What this trial is testingSorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade AstrocytomasWho this might be right forneurofibromatosis1 (NF1)Recurrent or Progressive Optic Pathway Gliomas (OPG)Recurrent or Progressive Low-grade Glioma NYU Langone Health 12
Early research (Phase 1)Study completedNCT00098761What this trial is testingVNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain TumorsWho this might be right forBrain and Central Nervous System Tumors Pediatric Brain Tumor Consortium 42
Testing effectiveness (Phase 2)Ended earlyNCT00003471What this trial is testingAntineoplaston Therapy in Treating Patients With Low-Grade AstrocytomaWho this might be right forLow-Grade Astrocytoma, Nos Burzynski Research Institute 7
Testing effectiveness (Phase 2)UnknownNCT02840409What this trial is testingVinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)Who this might be right forLow Grade Glioma The Hospital for Sick Children 109
Not applicableLooking for participantsNCT07506239What this trial is testingEfficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade GliomaWho this might be right forLow-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more University of California, San Francisco 40
Testing effectiveness (Phase 2)Study completedNCT00003466What this trial is testingTemozolomide in Treating Patients With Progressive Low-Grade GliomaWho this might be right forBrain and Central Nervous System Tumors Duke University 100
Large-scale testing (Phase 3)Study completedNCT00538850What this trial is testingFentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainWho this might be right forCancer INSYS Therapeutics Inc 130
Early research (Phase 1)Active Not RecruitingNCT07441707What this trial is testingAssess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain TumoursWho this might be right forLow-grade Glioma Ipsen 6
Testing effectiveness (Phase 2)Ended earlyNCT04544007What this trial is testingA Phase II Trial of Poly-ICLC for Low-Grade GliomasWho this might be right forNF1Low-grade Glioma University of Alabama at Birmingham 3
Testing effectiveness (Phase 2)WithdrawnNCT05222165What this trial is testingStudy With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 AlterationsWho this might be right forAdvanced Solid TumorCNS TumorRecurrent WHO Grade II Glioma Helsinn Healthcare SA
Testing effectiveness (Phase 2)Study completedNCT01734512What this trial is testingPNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in ChildrenWho this might be right forPediatric Recurrent Progressive Low-grade GliomasPediatric Progressive Low-grade Gliomas University of California, San Francisco 65
Testing effectiveness (Phase 2)Study completedNCT00381797What this trial is testingBevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade GliomaWho this might be right forChildhood Cerebral Anaplastic AstrocytomaChildhood OligodendrogliomaChildhood Spinal Cord Neoplasm+3 more National Cancer Institute (NCI) 97
Early research (Phase 1)Study completedNCT00272350What this trial is testingZD6474 to Treat Advanced Brain Cancer in PatientsWho this might be right forRecurrent High-Grade GliomasProgressive Low-Grade GliomasMalignant Gliomas National Cancer Institute (NCI) 83
Testing effectiveness (Phase 2)Looking for participantsNCT04923126What this trial is testingSJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade GliomaWho this might be right forLow-Grade GliomaRecurrent Low-Grade GliomaProgressive Low-Grade Glioma St. Jude Children's Research Hospital 132