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Results for “Proprotein Convertase Subtilisin/Kexin 9”

213 trials

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Showing 20 of 213 results

Testing effectiveness (Phase 2)Study completedNCT03815812
What this trial is testing

Multiple Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Chinese Patients With Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 60
Not applicableNot Yet RecruitingNCT07468500
What this trial is testing

Real World Adherence of PCSK9 Targeted Therapy

Who this might be right for
Dyslipidemia, Hypercholesterolemia
Novartis Pharmaceuticals 3,600
Testing effectiveness (Phase 2)Study completedNCT07301372
What this trial is testing

Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke

Who this might be right for
Acute Stroke
The Affiliated Hospital of Xuzhou Medical University 132
Large-scale testing (Phase 3)Not Yet RecruitingNCT07775339
What this trial is testing

Long-Term Efficacy and Safety of Lerodalcibep in Children and Adolescents With Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
LIB Therapeutics LLC 150
Large-scale testing (Phase 3)Not Yet RecruitingNCT07686796
What this trial is testing

Anti-PCSK9 Antibody Tafolecimab and Anti-PD-1 Antibody Sintilimab Combined With Neoadjuvant Chemoradiotherapy for pMMR/ MSS Locally Advanced Rectal Cancer : A Prospective, Multicenter, Randomized, Open-Label, Parallel-Controlled Trial

Who this might be right for
Local Advanced Rectal CancerPD-1 InhibitorPCSK9 Inhibitor+4 more
Guangdong Provincial People's Hospital 148
Large-scale testing (Phase 3)Not Yet RecruitingNCT07586540
What this trial is testing

Alirocumab for Stabilisation of Symptomatic Vulnerable Carotid Plaque

Who this might be right for
Carotid Stenosis
Middle East North Africa Stroke and Interventional Neurotherapies Organization 280
Not applicableLooking for participantsNCT05994274
What this trial is testing

A Clinical Study of Association Between Postoperative Dyslipidemia and Organ Rejection in Transplant Patients

Who this might be right for
Heart Transplant Failure and Rejection
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 80
Post-approval studies (Phase 4)Study completedNCT06431763
What this trial is testing

Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Who this might be right for
Hypercholesterolemia
Novartis Pharmaceuticals 402
Not applicableLooking for participantsNCT05765370
What this trial is testing

LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD)

Who this might be right for
Atherosclerotic Cardiovascular DiseaseOlder PatientsLDL Cholesterol
China National Center for Cardiovascular Diseases 4,200
Not applicableLooking for participantsNCT07036991
What this trial is testing

A Cohort Study Comparing PCSK9 Inhibitor Plus Statin With Statin Monotherapy for Carotid Artery Stenosis

Who this might be right for
Carotid Artery Stenosis
Changhai Hospital 406
Large-scale testing (Phase 3)Not Yet RecruitingNCT07119918
What this trial is testing

PCSK9 Inhibitor for Intracranial Atherosclerotic Symptomatic Stenosis

Who this might be right for
Symptomatic Intracranial Atherosclerotic Stenosis
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 5,276
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Early research (Phase 1)Study completedNCT03366688
What this trial is testing

Single Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Healthy Subjects.

Who this might be right for
Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 58
Testing effectiveness (Phase 2)Study completedNCT03537742
What this trial is testing

Cardiac Allograft Vasculopathy Inhibition With Alirocumab

Who this might be right for
Vasculopathy
Stanford University 114
Post-approval studies (Phase 4)Active Not RecruitingNCT05537948
What this trial is testing

Efficacy and Safety of Pitavastatin and PCSK9 Inhibitors in Liver Transplant Patients

Who this might be right for
DyslipidemiasHyperlipidemiasLiver Transplant Disorder+3 more
National Medical Research Center for Therapy and Preventive Medicine 59
Early research (Phase 1)Ended earlyNCT05128539
What this trial is testing

A Study Explore JS001+JS002 in Patients With Advanced Cancer

Who this might be right for
Advanced Cancer
Shanghai Junshi Bioscience Co., Ltd. 9
Not applicableStudy completedNCT02674659
What this trial is testing

The Effect of Resistance Training on Proprotein Subtilisin Convertase Kexin 9 Level After Coronary Bypass Surgery

Who this might be right for
Coronary Artery Disease
National Cardiovascular Center Harapan Kita Hospital Indonesia 87
Testing effectiveness (Phase 2)Ended earlyNCT03004001
What this trial is testing

Effect of PCSK9-Antibody (Alirocumab) on Dyslipidemia Secondary to Nephrotic Syndrome

Who this might be right for
Nephrotic Syndrome
Gloria Vega 3
Not applicableLooking for participantsNCT06373913
What this trial is testing

The Role of Proprotein-convertase-subtilisin/Kexin-type 9 in Kidney Damage in Nephrotic Syndrom

Who this might be right for
HyperlipidemiasNephrotic Syndrome
Kolding Sygehus 75
Post-approval studies (Phase 4)Looking for participantsNCT06902740
What this trial is testing

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

Who this might be right for
Intracranial AtherosclerosisIntracranial Artery StenosisAtherosclerotic Plaque
Peking Union Medical College Hospital 300
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