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Results for “Proprotein Convertase Subtilisin/Kexin 9”

200 trials

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Showing 20 of 200 results

Not applicableNot Yet RecruitingNCT06730802
What this trial is testing

Protective Effect of PCSK9 Inhibitor Against Negative Inflammatory Response and Organ Dysfunction After Coronary Artery Bypass Grafting (PANDA VIII)

Who this might be right for
Myocardial Ischaemic SyndromeCoronary Heart Disease
Nanjing Medical University 400
Not applicableNot Yet RecruitingNCT07341958
What this trial is testing

INtensive liPid-lowering Therapy for Acute High-risk IntracRanial or Extracranial atheroSclerosis -II (INSPIRES-2)

Who this might be right for
Ischemic Stroke or High-risk TIA (ABCD² ≥ 4)
Beijing Tiantan Hospital 242
Not applicableUnknownNCT04087915
What this trial is testing

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With High Risk Coronary Artery Disease (FORWARD)

Who this might be right for
DyslipidemiaHigh Risk Coronary Artery Disease
Beijing Anzhen Hospital 1,000
Post-approval studies (Phase 4)Not Yet RecruitingNCT06381947
What this trial is testing

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients

Who this might be right for
DyslipidemiasStatin Adverse ReactionCardiovascular Diseases+1 more
University of Salerno 130
Post-approval studies (Phase 4)Study completedNCT02938949
What this trial is testing

Alirocumab in Patients With Acute Myocardial Infarction

Who this might be right for
Myocardial InfarctionHypercholesterolemia
Virginia Commonwealth University 20
Post-approval studies (Phase 4)Looking for participantsNCT06902740
What this trial is testing

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

Who this might be right for
Intracranial AtherosclerosisIntracranial Artery StenosisAtherosclerotic Plaque
Peking Union Medical College Hospital 300
Not applicableStudy completedNCT03273972
What this trial is testing

INvestigating the Lowest Threshold of Vascular bENefits From LDL Lowering With a PCSK9 InhibiTor in healthY Volunteers

Who this might be right for
AtherosclerosisCardiovascular Diseases
Cambridge University Hospitals NHS Foundation Trust 30
Post-approval studies (Phase 4)UnknownNCT05802108
What this trial is testing

Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Who this might be right for
Adverse Effect of Cardiovascular Medications (Diagnosis)
Zibo Central Hospital 60
Large-scale testing (Phase 3)Looking for participantsNCT07002476
What this trial is testing

Early Aggressive Strategy for Treatment of Lipid-Lowering in Acute Ischemic Stroke Delivered With Endovascular Therapy for Large Artery Occlusion

Who this might be right for
Stroke
Shanghai East Hospital 652
Large-scale testing (Phase 3)Study completedNCT04797104
What this trial is testing

Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction

Who this might be right for
Heterozygous Familial Hypercholesterolemia
LIB Therapeutics LLC 478
Very early researchActive Not RecruitingNCT04862260
What this trial is testing

Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic Ductal AdenocarcinomaPancreatic CancerPancreas Cancer+1 more
CHU de Quebec-Universite Laval 3
Testing effectiveness (Phase 2)UnknownNCT03051360
What this trial is testing

PCSK9 Inhibitors in the Progression of Aortic Stenosis

Who this might be right for
Aortic Valve Stenosis
Seoul National University Hospital 140
Not applicableNot Yet RecruitingNCT06791031
What this trial is testing

PCSK9 inhibitoRs for Early Passivation of coRonary athEroSclerotic plaqueS in Acute Coronary Syndromes (REPRESS)

Who this might be right for
Coronary Artery Disease
West China Hospital 212
Not applicableStudy completedNCT01109706
What this trial is testing

Relevance of Plasma PCSK9 Concentration as a Biomarker in Acute Coronary Syndrome.

Who this might be right for
Acute Coronary Syndrome
Nantes University Hospital 175
Large-scale testing (Phase 3)Study completedNCT01764633
What this trial is testing

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Who this might be right for
Dyslipidemia
Amgen 27,564
Testing effectiveness (Phase 2)Study completedNCT07278830
What this trial is testing

A Phase II Study to Evaluate the Safety and Efficacy of SAL003 Combined With Atorvastatin in Hypercholesterolemia and Mixed Dyslipidemia

Who this might be right for
Hypercholesterolemia and Mixed Dyslipidemia
Shenzhen Salubris Pharmaceuticals Co., Ltd. 214
Large-scale testing (Phase 3)Looking for participantsNCT04968509
What this trial is testing

Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis

Who this might be right for
Aortic Stenosis
Beijing Anzhen Hospital 160
Testing effectiveness (Phase 2)Study completedNCT01375764
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Who this might be right for
Hyperlipidemia
Amgen 160
Testing effectiveness (Phase 2)Study completedNCT04173793
What this trial is testing

PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Akeso 109
Post-approval studies (Phase 4)Looking for participantsNCT05292404
What this trial is testing

Impact of Early PCSK9 Inhibitor Treatment on Heart After Acute Myocardium Infarction

Who this might be right for
Acute Myocardial Infarction
Shanghai Tong Ren Hospital 160
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