Not applicableNot Yet RecruitingNCT07712042What this trial is testingTafolecimab in Hyperlipidemia: A Study of Different Dosing IntervalsWho this might be right forHyperlipidemia Mei Gao 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05553834What this trial is testingPCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell LungWho this might be right forNon-small Cell Lung Cancer (NSCLC) Duke University 60
Post-approval studies (Phase 4)Study completedNCT06431763What this trial is testingInvestigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.Who this might be right forHypercholesterolemia Novartis Pharmaceuticals 402
Testing effectiveness (Phase 2)Study completedNCT03193047What this trial is testingEvaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor TherapyWho this might be right forHypercholesterolemia Esperion Therapeutics, Inc. 59
Very early researchActive Not RecruitingNCT04862260What this trial is testingCholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic AdenocarcinomaWho this might be right forPancreatic Ductal AdenocarcinomaPancreatic CancerPancreas Cancer+1 more CHU de Quebec-Universite Laval 3
Not applicableNot Yet RecruitingNCT06854523What this trial is testingAssessing Coronary Non-Culprit Plaque Early with Start of PCSK9 Inhibitors in Acute Myocardial Infarction (ACCESS-AMI)Who this might be right forAcute Myocardial Infarction Yun Dai Chen 300
Post-approval studies (Phase 4)Not Yet RecruitingNCT07803679What this trial is testingA Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in Participants With Subclinical AtheromaWho this might be right forCoronary Artery DiseaseHypercholesterolemiaAtheroma+1 more Amgen 308
Testing effectiveness (Phase 2)UnknownNCT04338165What this trial is testingImpact of PCSK9 Inhibitors on Coronary Microvascular Dysfunction in Patients With Atherosclerotic Cardiovascular Disease Proved by Myocardial Ischemia and Needing CoronarographyWho this might be right forAtherosclerotic Cardiovascular Disease University Hospital, Grenoble 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07621562What this trial is testingTafolecimab Combined With Sintilimab and SOX in the Treatment of pMMR/MSS Gastric CancerWho this might be right forGastric AdenocarcinomaEsophagogastric Juction CancerProficient Mismatch Repair First Affiliated Hospital of Zhejiang University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07391722What this trial is testingDNV001 Injection in Patients With HypercholesterolemiaWho this might be right forPrimary Hypercholesterolemia Hangzhou Dinovate Biotech Co., Ltd 120
Large-scale testing (Phase 3)Not Yet RecruitingNCT07775339What this trial is testingLong-Term Efficacy and Safety of Lerodalcibep in Children and Adolescents With Familial HypercholesterolemiaWho this might be right forHeterozygous Familial Hypercholesterolemia (HeFH) LIB Therapeutics LLC 150
Large-scale testing (Phase 3)Looking for participantsNCT06568471What this trial is testingA Study on Efficacy and Safety of HST101 in Chinese Patients with HypercholesterolemiaWho this might be right forHypercholesterolemiaDyslipidemiasPrimary Hypercholesterolemia+4 more Hasten Biopharmaceutical Co., Ltd. 210
Large-scale testing (Phase 3)Ended earlyNCT02524106What this trial is testingBococizumab HIV Evaluation (B-HIVE) StudyWho this might be right forDyslipidemiaCardiovascular Disease University of California, San Francisco 11
Large-scale testing (Phase 3)Study completedNCT05004675What this trial is testingTrial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD PatientsWho this might be right forHypercholesterolemiaAtherosclerotic Ischemic Disease LIB Therapeutics LLC 166
Not applicableUnknownNCT04730648What this trial is testingAcute Myocardial Infarction and Unstable Angina Patients With PCSK9 Inhibitor Usage StudyWho this might be right forLipid MetabolismCardiovascular Diseases Shenzhen People's Hospital 100
Not applicableStudy completedNCT05184530What this trial is testingIn-hospital Initiation of PCSK9 Inhibitor in Patients With Acute Myocardial InfarctionWho this might be right forCoronary Disease First Affiliated Hospital Xi'an Jiaotong University 7,556
Post-approval studies (Phase 4)UnknownNCT04100434What this trial is testingEffect of Evolocumab Added to Moderate-Intensity Statin Therapy on LDL-C Lowering and Cardiovascular Adverse Events in Patients With Acute Coronary SyndromeWho this might be right forAcute Coronary SyndromeProprotein Convertase Subtilisin/Kexin Type 9 Inhibitor Tianjin Chest Hospital 500
Not applicableLooking for participantsNCT07540741What this trial is testingEfficacy and Safety of PCSK9 Inhibitors in Patients With Large-Artery Atherosclerosis (LAA) Ischemic StrokeWho this might be right forAcute Ischemic Stroke First Affiliated Hospital of Harbin Medical University 1,000
Large-scale testing (Phase 3)UnknownNCT03634293What this trial is testingTreatment of Severe Infection With Antihyperlipidemia DrugWho this might be right forSepsisSeptic Shock Wolfson Medical Center 712
Testing effectiveness (Phase 2)UnknownNCT04101643What this trial is testingPCSK9 Inhibitor Treatment for Patients With SPG5Who this might be right forHereditary Spastic Paraplegia Type 5 First Affiliated Hospital of Fujian Medical University 30