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Results for “Protein Kinases”

276 trials

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Showing 20 of 276 results

Not applicableEnded earlyNCT02455024
What this trial is testing

An Observational Registry to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With ICLUSIG®

Who this might be right for
Myeloid Leukemia, Chronic-Phase, Accelerated-Phase, Blast-Phase, Ph+ALL
Ariad Pharmaceuticals 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT05585320
What this trial is testing

A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorPancreatic AdenocarcinomaMalignant Melanoma (Cutaneous)+1 more
Immuneering Corporation 209
Early research (Phase 1)Study completedNCT00004059
What this trial is testing

Fluorouracil Plus UCN-01 in Treating Patients With Advanced or Refractory Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT00443976
What this trial is testing

Aurora Kinase Inhibitor AT9283 in Treating Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Non-Hodgkins LymphomaUnspecified Adult Solid Tumor, Protocol Specific
NCIC Clinical Trials Group 35
Not applicableStudy completedNCT04163757
What this trial is testing

The Effects of Crocin Supplementation on Metabolic Parameters, Oxidative Stress, AMP- Activated Protein Kinase and Inflammation-promoting Genes Expression in Peripheral Blood Mononuclear Cells in Patients With Type 2 Diabetes

Who this might be right for
Type 2 Diabetes
National Nutrition and Food Technology Institute 50
Early research (Phase 1)Looking for participantsNCT05131022
What this trial is testing

NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)Diffuse Large B Cell Lymphoma (DLBCL)+6 more
Nurix Therapeutics, Inc. 572
Not applicableEnded earlyNCT02071719
What this trial is testing

Prediction of Response to Kinase Inhibitors Based on Protein Phosphorylation Profiles in Tumor Tissue From Advanced Renal Cell Cancer Patients

Who this might be right for
Renal Cell Cancer
M. Labots 6
Large-scale testing (Phase 3)Looking for participantsNCT06988475
What this trial is testing

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

Who this might be right for
Solid TumourHaematological MalignancyMalignant Neoplasm+8 more
Cancer Research UK 30
Large-scale testing (Phase 3)Looking for participantsNCT06008106
What this trial is testing

Comparing Tunlametinib Capsules and Combination Chemotherapy in Advanced NRAS-mutant Melanoma

Who this might be right for
Melanoma
Shanghai Kechow Pharma, Inc. 165
Not applicableLooking for participantsNCT06497829
What this trial is testing

Geranylgeraniol Supplementation in Patients With Mevalonate Kinase Deficiency

Who this might be right for
Mevalonate Kinase Deficiency
University Hospital, Motol 6
Early research (Phase 1)Ended earlyNCT03116971
What this trial is testing

Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)

Who this might be right for
Small Cell Lung Cancer
EMD Serono Research & Development Institute, Inc. 2
Testing effectiveness (Phase 2)UnknownNCT00606164
What this trial is testing

Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics Study of Bryostatin 1 in Patients With Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Blanchette Rockefeller Neurosciences Insitute 9
Early research (Phase 1)Study completedNCT02516813
What this trial is testing

Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy

Who this might be right for
Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc. 52
Testing effectiveness (Phase 2)Study completedNCT01229150
What this trial is testing

Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...

Who this might be right for
Non Small Cell Lung Carcinoma
National Cancer Institute (NCI) 89
Testing effectiveness (Phase 2)WithdrawnNCT04953052
What this trial is testing

Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and Blood of Adults With COVID-19 Needing Mechanical Ventilation and Supportive Care.

Who this might be right for
Acute Respiratory Distress SyndromeCOVID-19 Acute Respiratory Distress SyndromeCovid19+2 more
Exvastat Ltd.
Testing effectiveness (Phase 2)Study completedNCT01291017
What this trial is testing

Cyclin Dependent Kinase (CDK)4/6 Inhibitor, PD0332991 in Advanced Non-small Cell Lung Cancer NSCLC.

Who this might be right for
Non-small Cell Lung Cancer
University of Florida 19
Early research (Phase 1)Looking for participantsNCT06395285
What this trial is testing

Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome Patients

Who this might be right for
ROSAH
Shanghai Yao Yuan Biotechnology Ltd. (also known as Drug Farm) 12
Early research (Phase 1)Study completedNCT05002140
What this trial is testing

Trial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients

Who this might be right for
MetastasisLocally Advanced Solid TumorRecurrent Cancer
XRad Therapeutics Inc 12
Not applicableUnknownNCT04156425
What this trial is testing

The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive Depression

Who this might be right for
Major Depressive Disorder
Shanghai Mental Health Center 180
Testing effectiveness (Phase 2)Active Not RecruitingNCT05907954
What this trial is testing

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

Who this might be right for
Uveal Melanoma
IDEAYA Biosciences 160
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