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Results for “Protein Kinases”

270 trials

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Showing 20 of 270 results

Testing effectiveness (Phase 2)Study completedNCT01962792
What this trial is testing

Study of BTK Inhibitor, Ibrutinib in Combination With Carfilzomib in Subjects With Relapsed and Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Pharmacyclics LLC. 84
Early research (Phase 1)Ended earlyNCT01668017
What this trial is testing

A Multicentre, Open Label, Phase 1 Trial in Japan of the Mitogen Activated Protein Extracellular Signal Regulated Kinase (MEK) Inhibitor Pimasertib Given Orally to Subjects With Solid Tumors as Monotherapy

Who this might be right for
Advanced Solid TumorsHepatocellular Carcinoma
Merck KGaA, Darmstadt, Germany 26
Early research (Phase 1)Study completedNCT00884416
What this trial is testing

Sorafenib in Newly Diagnosed High Grade Glioma

Who this might be right for
GlioblastomaGliosarcomaAnaplastic Astrocytoma+2 more
University Hospital, Geneva 17
Not applicableUnknownNCT04353882
What this trial is testing

Mu Opioid Receptor 1 Expression and Activation Patterns in Colorectal Cancer

Who this might be right for
Colorectal Surgery for Stage II / III Primary Colorectal Cancer
Hospital Universitario La Fe 20
Testing effectiveness (Phase 2)Study completedNCT01303380
What this trial is testing

Canakinumab in Patients With Active Hyper-IgD Syndrome

Who this might be right for
Mevalonate Kinase Deficiency
Novartis Pharmaceuticals 9
Testing effectiveness (Phase 2)Study completedNCT00095680
What this trial is testing

Extension Study of the Efficacy and Safety of Oral SCIO-469 in Relapsed, Refractory Patients With Multiple Myeloma

Who this might be right for
Multiple Myeloma
Scios, Inc. 30
Early research (Phase 1)Study completedNCT02316197
What this trial is testing

Clinical Phase I Study Investigating MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Advanced Solid Tumors or Chronic Lymphocytic Leukemia

Who this might be right for
Advanced Solid TumorsChronic Lymphocytic Leukemia
Merck KGaA, Darmstadt, Germany 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT05585320
What this trial is testing

A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorPancreatic AdenocarcinomaMalignant Melanoma (Cutaneous)+1 more
Immuneering Corporation 209
Testing effectiveness (Phase 2)Study completedNCT01039948
What this trial is testing

A Phase 1b/2 Study in Asian Subjects With Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small Cell-LungLung NeoplasmsLung Cancer+1 more
AVEO Pharmaceuticals, Inc. 203
Testing effectiveness (Phase 2)Study completedNCT01642082
What this trial is testing

Dalantercept in Treating Patients With Recurrent or Persistent Endometrial Cancer

Who this might be right for
Endometrial AdenocarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Mixed Adenocarcinoma+6 more
Gynecologic Oncology Group 28
Large-scale testing (Phase 3)Study completedNCT00017407
What this trial is testing

Carboplatin and Paclitaxel With or Without ISIS 3521 in Treating Patients With Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
Ionis Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT01551693
What this trial is testing

STA-9090(Ganetespib) in Patients With Unresectable Stage III or Stage IV Melanoma

Who this might be right for
Melanoma
Dana-Farber Cancer Institute 3
Testing effectiveness (Phase 2)Study completedNCT01750281
What this trial is testing

Assess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment.

Who this might be right for
Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV
AstraZeneca 212
Testing effectiveness (Phase 2)UnknownNCT06098872
What this trial is testing

Pilot Study on Trametinib for Surgical Unruptured AVMs

Who this might be right for
Arteriovenous Malformations
University Health Network, Toronto 10
Large-scale testing (Phase 3)Looking for participantsNCT06988475
What this trial is testing

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

Who this might be right for
Solid TumourHaematological MalignancyMalignant Neoplasm+8 more
Cancer Research UK 30
Not applicableNot Yet RecruitingNCT07211412
What this trial is testing

Acute Cryotherapy on Musculoskeletal Function and Biomarkers

Who this might be right for
Exercise Induced Muscle DamageCryotherapy
University of Texas, El Paso 60
Early research (Phase 1)Looking for participantsNCT05780034
What this trial is testing

AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

Who this might be right for
Relapsed/Refractory B-cell Malignancies
Accutar Biotechnology Inc 60
Not applicableLooking for participantsNCT04965129
What this trial is testing

Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet

Who this might be right for
Lung Cancer
Universidade Federal do Rio de Janeiro 50
Not applicableStudy completedNCT01099410
What this trial is testing

Apoptotic Cell (AC) Uptake by Human Alveolar Macrophages (AM)

Who this might be right for
Chronic Obstructive Pulmonary Disease
VA Office of Research and Development 17
Early research (Phase 1)Looking for participantsNCT07343960
What this trial is testing

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

Who this might be right for
Moderate Hepatic Impairment
AstraZeneca 20
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