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Results for “Pucotenlimab”

51 trials

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Showing 20 of 51 results

Testing effectiveness (Phase 2)Looking for participantsNCT06959108
What this trial is testing

Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck

Who this might be right for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Groupe Oncologie Radiotherapie Tete et Cou 106
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07767266
What this trial is testing

Neoadjuvant Pucotenlimab and Becotatug Vedotin for Locally Advanced Penile Cancer

Who this might be right for
Penile CancerPenile Squamous Cell Carcinoma (PSCC)
Sun Yat-sen University 29
Large-scale testing (Phase 3)Looking for participantsNCT06976190
What this trial is testing

MRG003 in Combination With Pucotenlimab Versus Chemotherapy in the Treatment of Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma

Who this might be right for
Recurrent or Metastatic Nasopharyngeal Carcinoma
Lepu Biopharma Co., Ltd. 446
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07766889
What this trial is testing

Neoadjuvant Presurgical Becotatug Vedotin (MRG003) Plus Pucotenlimab (HX008) in Oral Cavity Squamous Cell Carcinoma

Who this might be right for
Oral Squamous Cell CarcinomaHead and Neck CancerLocally Advanced Head and Neck Cancer+1 more
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07545083
What this trial is testing

Neoadjuvant Becotatug Vedotin Plus Pucotenlimab in Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma (OSCC)

Who this might be right for
Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma
Shanghai Zhongshan Hospital 26
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06895369
What this trial is testing

The Efficacy and Safety of Pucotenlimab Combined With TP Chemotherapy as Neoadjuvant Therapy for Locally Advanced HNSCC

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Sir Run Run Shaw Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07501104
What this trial is testing

Neoadjuvant Pucotenlimab Combined With Lenvatinib and Temozolomide in Resectable Stage IIB/III Acral Melanoma

Who this might be right for
Melanoma (Skin Cancer)
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT06524466
What this trial is testing

Neoadjuvant SBRT Combined With Lenvatinib and Pucotenlimab for Resectable Hepatocellular Carcinoma

Who this might be right for
Resectable Hepatocellular CarcinomaMacrovascular InvasionCNLC IIIA Stage
Sun Yat-sen University 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07514533
What this trial is testing

The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma
Sir Run Run Shaw Hospital 60
Testing effectiveness (Phase 2)Looking for participantsNCT06770270
What this trial is testing

Pucotenlimab Plus Radiotherapy and Chemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cance(PUCRT)

Who this might be right for
Rectal Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine 68
Testing effectiveness (Phase 2)Looking for participantsNCT06456892
What this trial is testing

Effectiveness of Pucotenlimab Combined With Standard Chemotherapy Regimen

Who this might be right for
RhabdomyosarcomaPediatric Cancer
Sun Yat-sen University 82
Very early researchEnrolling By InvitationNCT07356466
What this trial is testing

Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric (Stomach) Cancer
Fujian Medical University 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07354984
What this trial is testing

A Single-Arm Phase II Clinical Study of Docetaxel Combined With Nimotuzumab and Pucotenlimab as Second-Line and Beyond Therapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Sun Yat-sen University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07394244
What this trial is testing

Pucotenlimab Combined With Becotatug Vedotin in Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma (CSCC)
Fudan University 38
Testing effectiveness (Phase 2)Looking for participantsNCT07448142
What this trial is testing

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Sun Yat-sen University 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07628855
What this trial is testing

A Prospective, Single-arm, Phase II Clinical Trial of Becotatug Vedotin for Injection Combined With Pucotenlimab Injection as a First-line Treatment for Platinum-intolerant Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
HNPCC
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07589049
What this trial is testing

Becotatug Vedotin Combined With Pucotenlimab as Neoadjuvant Therapy for Resectable Recurrent Head and Neck Squamous Cell Carcinoma After Progression on Immunotherapy: A Prospective Phase II Study

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Sun Yat-sen University 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07649980
What this trial is testing

Becotatug Vedotin Plus Pucotenlimab for Advanced Biliary Tract Cancer, Phase II

Who this might be right for
Biliary Tract Cancer (BTC)EGFR-positive Advanced Biliary Tract Carcinoma
HuiKai Li 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07651007
What this trial is testing

Short-course RT Followed by NALIRIFOX Plus Pucotenlimab as Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer With MSS/pMMR

Who this might be right for
Advanced Rectal Cancer
Wang Xin 29
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06530914
What this trial is testing

A Phase II Study of MRG003 Injection Combined With Pucotenlimab Injection ± Cisplatin Injection in the Neoadjuvant Treatment Locally Advanced EGFR-positive Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)
Lei Liu 30
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