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Results for “Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency”

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Showing 20 of 0 results

Not applicableStudy completedNCT00001462
What this trial is testing

Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals

Who this might be right for
EmphysemaLung Diseases, ObstructiveAlpha 1-Antitrypsin Deficiency
National Heart, Lung, and Blood Institute (NHLBI) 60
Post-approval studies (Phase 4)Not Yet RecruitingNCT07326592
What this trial is testing

Phase 4, Double-blind Study Evaluating the Response on Computed Tomography (CT) Lung Density Decline Rates of Respreeza / Zemaira Weekly for 3 Years in Adults With alpha1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha1 Antitrypsin DeficiencyAlpha1-Proteinase Inhibitor DeficiencyEmphysema
CSL Behring 270
Not applicableNot Yet RecruitingNCT07145385
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Deficiency in Non-Cirrhotic Liver Cancer

Who this might be right for
Retrospective Cohort of Patients Diagnosed With HCC on Non-Cirrhotic Liver
University Hospital, Bordeaux 71
Early research (Phase 1)Ended earlyNCT01183468
What this trial is testing

A Research Trial of Aralast in New Onset Diabetes (RETAIN)

Who this might be right for
Diabetes Mellitus, Type 1
National Institute of Allergy and Infectious Diseases (NIAID) 17
Early research (Phase 1)Study completedNCT04174118
What this trial is testing

Study of DCR-A1AT in Healthy Adult Volunteers

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 30
Early research (Phase 1)Active Not RecruitingNCT06738017
What this trial is testing

Study of BMN 349 Single Dose in PiZZ and PiMZ/MASH Adult Participants

Who this might be right for
Alpha 1-Antitrypsin Deficiency
BioMarin Pharmaceutical 6
Testing effectiveness (Phase 2)Ended earlyNCT06677307
What this trial is testing

A Phase 1/2a, Single- and Multiple-dose Escalation Study of KRRO-110

Who this might be right for
Alpha-1 Anti-trypsin DeficiencyAATD
Korro Bio, Inc. 42
Not applicableStudy completedNCT01419158
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)

Who this might be right for
Alpha-1 Antitrypsin DeficiencyChronic Obstructive Pulmonary Disease
Alpha-1 Foundation 3,457
Early research (Phase 1)Study completedNCT03815396
What this trial is testing

Phase 1 Study to Assess the Safety, PK and PD of INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin DeficiencyAATD
Inhibrx Biosciences, Inc 31
Not applicableStudy completedNCT02922751
What this trial is testing

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

Who this might be right for
Biliary AtresiaAlagille SyndromeAlpha1 Anti-Trypsin Deficiency+3 more
Arbor Research Collaborative for Health 552
Testing effectiveness (Phase 2)Study completedNCT01054339
What this trial is testing

Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Beacon Therapeutics 9
Early research (Phase 1)Study completedNCT05727800
What this trial is testing

A Phase 1, First-in-human Study of VX-668

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 114
Not applicableEnded earlyNCT02502201
What this trial is testing

Environment Effect on Six-Minute Walk Test Performance

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha-1 Antitrypsin Deficiency
University of Florida 27
Not applicableEnded earlyNCT01357460
What this trial is testing

Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency

Who this might be right for
Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)
Heidelberg University 18
Testing effectiveness (Phase 2)WithdrawnNCT06622668
What this trial is testing

NTLA-3001 in Adults with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease

Who this might be right for
Lung DiseasePulmonary DiseaseAATD+2 more
Intellia Therapeutics
Very early researchActive Not RecruitingNCT07193615
What this trial is testing

Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
RenJi Hospital 18
Testing effectiveness (Phase 2)Study completedNCT00067756
What this trial is testing

4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?

Who this might be right for
Alpha 1-Antitrypsin Deficiency
University of Florida 12
Not applicableUnknownNCT03455686
What this trial is testing

Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

Who this might be right for
AsthmaChronic Obstructive Pulmonary DiseaseBronchiectasis+5 more
McMaster University 60
Large-scale testing (Phase 3)Looking for participantsNCT07555483
What this trial is testing

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC 40
Large-scale testing (Phase 3)Looking for participantsNCT05677971
What this trial is testing

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 160
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