Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Pure Autonomic Failure (PAF)”

10 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 10 of 10 results

Large-scale testing (Phase 3)Study completedNCT03750552
What this trial is testing

Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

Who this might be right for
Symptomatic Neurogenic Orthostatic Hypotension
Theravance Biopharma 195
Testing effectiveness (Phase 2)Study completedNCT02705755
What this trial is testing

TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)

Who this might be right for
Neurogenic Orthostatic HypotensionMultiple System Atrophy (MSA) With Orthostatic HypotensionPure Autonomic Failure+5 more
Theravance Biopharma 34
Large-scale testing (Phase 3)Study completedNCT00633880
What this trial is testing

Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)

Who this might be right for
Symptomatic Neurogenic Orthostatic Hypotension (NOH)Non-diabetic NeuropathyPrimary Autonomic Failure+1 more
Chelsea Therapeutics 181
Not applicableStudy completedNCT04875949
What this trial is testing

Anti-Cholinergic Receptors Antibodies, Autonomic Profile and Dysautonomia Symptoms in PAF, ALS and POTS (DISAUT-AB)

Who this might be right for
Pure Autonomic FailureAmyotrophic Lateral SclerosisPostural Orthostatic Tachycardia Syndrome+1 more
Istituto Clinico Humanitas 75
Large-scale testing (Phase 3)Study completedNCT00782340
What this trial is testing

A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa

Who this might be right for
Symptomatic Neurogenic Orthostatic Hypotension (NOH)Non-diabetic NeuropathyPrimary Autonomic Failure+1 more
Chelsea Therapeutics 263
Large-scale testing (Phase 3)Study completedNCT00738062
What this trial is testing

Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)

Who this might be right for
Neurogenic Orthostatic HypotensionNon-Diabetic Autonomic NeuropathyMultiple System Atrophy+1 more
Chelsea Therapeutics 103
Large-scale testing (Phase 3)Ended earlyNCT01927055
What this trial is testing

A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy

Who this might be right for
Symptomatic Neurogenic Orthostatic HypotensionParkinson's DiseaseMultiple Systems Atrophy+2 more
Chelsea Therapeutics 61
Testing effectiveness (Phase 2)UnknownNCT00758849
What this trial is testing

Fipamezole in Neurogenic Orthostatic Hypotension

Who this might be right for
Symptomatic Neurogenic Orthostatic Hypotension (NOH)Parkinson's DiseaseMultiple System Atrophy
Juvantia Pharma Ltd 24
Large-scale testing (Phase 3)Ended earlyNCT03829657
What this trial is testing

Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

Who this might be right for
Symptomatic Neurogenic Orthostatic HypotensionMSAParkinson's Disease (PD)+1 more
Theravance Biopharma 203
Large-scale testing (Phase 3)Ended earlyNCT04095793
What this trial is testing

Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

Who this might be right for
Symptomatic Neurogenic Orthostatic Hypotension
Theravance Biopharma 110