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Results for “RAF Mutation”

40 trials

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Showing 20 of 40 results

Not applicableStudy completedNCT04236102
What this trial is testing

KEBI-Cyto Study - Use of the Biocartis Idylla

Who this might be right for
Pancreatic AdenocarcinomaLung Cancer
Royal Cornwall Hospitals Trust 55
Early research (Phase 1)Ended earlyNCT05831995
What this trial is testing

Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.

Who this might be right for
Advanced Solid TumorRAS MutationRAF Mutation+1 more
ABM Therapeutics Corporation 12
Early research (Phase 1)Ended earlyNCT04249843
What this trial is testing

Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors

Who this might be right for
Solid TumorB-Raf Mutation-Related Tumors
MapKure, LLC 109
Early research (Phase 1)Looking for participantsNCT06299839
What this trial is testing

PAS-004 in Patients With Advanced Solid Tumors

Who this might be right for
RAS MutationNF1 MutationRAF Mutation+1 more
Pasithea Therapeutics Corp. 48
Large-scale testing (Phase 3)Looking for participantsNCT07440290
What this trial is testing

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+17 more
Cancer Research UK 30
Early research (Phase 1)Study completedNCT01337765
What this trial is testing

Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients

Who this might be right for
Unspecified Adult Solid Tumor, Protocol SpecificSolid Tumor
Pfizer 29
Testing effectiveness (Phase 2)Active Not RecruitingNCT04625270
What this trial is testing

Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation

Who this might be right for
Low Grade Ovarian Serous AdenocarcinomaOvarian Cancer
Verastem, Inc. 225
Early research (Phase 1)Active Not RecruitingNCT06104488
What this trial is testing

Avutometinib for People With Solid Tumor Cancers

Who this might be right for
Refractory CancerCNS TumorsCNS Tumor, Adult+12 more
Memorial Sloan Kettering Cancer Center 3
Testing effectiveness (Phase 2)Study completedNCT02768207
What this trial is testing

Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma

Who this might be right for
Metastatic Melanoma
Hoffmann-La Roche 40
Early research (Phase 1)Ended earlyNCT07121829
What this trial is testing

Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors

Who this might be right for
MelanomaSolid TumorPilocytic Astrocytoma+7 more
Day One Biopharmaceuticals, Inc. 44
Early research (Phase 1)Ended earlyNCT04800822
What this trial is testing

PF-07284892 in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Pfizer 53
Early research (Phase 1)Study completedNCT01436656
What this trial is testing

A Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant Melanoma

Who this might be right for
Melanoma and Metastatic Colorectal Cancer
Pfizer 107
Testing effectiveness (Phase 2)Ended earlyNCT04585815
What this trial is testing

Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Pfizer 34
Not applicableLooking for participantsNCT05868629
What this trial is testing

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

Who this might be right for
Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors
Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Study completedNCT01116271
What this trial is testing

Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec

Who this might be right for
Colorectal Cancer
AstraZeneca 32
Testing effectiveness (Phase 2)Study completedNCT01086267
What this trial is testing

Safety and Efficacy Study of BMS-908662 Alone or in Combination With Cetuximab in Subjects With K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Bristol-Myers Squibb 17
Not applicableUnknownNCT06081270
What this trial is testing

Prospective Study on Resistance-associated Mutations in Metastatic Lung Cancer

Who this might be right for
Lung Cancer
University of Milano Bicocca 20
Testing effectiveness (Phase 2)Study completedNCT01781026
What this trial is testing

Phase 2 Study of Neoadjuvant Vemurafenib in Melanoma Patients With Untreated Brain Metastases

Who this might be right for
Melanoma
Yale University 2
Testing effectiveness (Phase 2)Ended earlyNCT01514864
What this trial is testing

Trial of Dasatinib in Patients With Advanced Cancers Harboring DDR2 Mutation or Inactivating B-RAF Mutation

Who this might be right for
Carcinoma, Non-small Cell Lung
Bristol-Myers Squibb 19
Testing effectiveness (Phase 2)Study completedNCT05068752
What this trial is testing

Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer

Who this might be right for
Pancreas Cancer
HonorHealth Research Institute 10
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