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Results for “RC48”

79 trials

Showing 20 of 79 results

Testing effectiveness (Phase 2)Looking for participantsNCT07474324
What this trial is testing

Disitamab Vedotin Combined With SOX Regimen Versus SOX Alone as Adjuvant Therapy for HER2-Moderate/High Expressing Stage Ⅲ Gastric Cancer: A Prospective, Multicenter, Randomized, Phase Ⅱ Clinical Trial

Who this might be right for
GC/GEJC
The First Affiliated Hospital with Nanjing Medical University 124
Testing effectiveness (Phase 2)UnknownNCT05957757
What this trial is testing

RC48 Combined With Tislelizumab for Bladder Sparing Treatment in NMIBC With BCG Treatment Failure and HER2 Expression

Who this might be right for
Non-Muscle Invasive Bladder CancerHER2
RenJi Hospital 20
Testing effectiveness (Phase 2)UnknownNCT05016973
What this trial is testing

A Clinical Study of RC48-ADC Combined With Triplizumab For Treatment of Myometrial Invasive Bladder Cancer

Who this might be right for
Bladder Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05356351
What this trial is testing

An Open-label, Single-arm, Multicenter Phase II Clinical Study： Evaluating RC48-ADC Combined With Triplizumab in the Neoadjuvant Treatment of Her2-positive Muscle-invasive Bladder Cancer

Who this might be right for
Neoadjuvant Treatment of Her2-positive Muscle-invasive Bladder Cance
Tianjin Medical University Cancer Institute and Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06791070
What this trial is testing

RC48-ADC Combined With JS001 for Advanced Extramammary Paget Disease of the Scrotum

Who this might be right for
Paget Disease, ExtramammaryScrotum Disease
Fujian Medical University Union Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06155396
What this trial is testing

RC48-ADC Combination With Zimberelimab Injection Therapies at Least First-line Platinum-containing Standard Therapy Failed With Recurrent or Metastatic Cervical Cancer

Who this might be right for
Cervical Cancer
RemeGen Co., Ltd. 116
Testing effectiveness (Phase 2)Looking for participantsNCT05403242
What this trial is testing

RC48-ADC Combined With S-1 for First-line Treatment of Advanced Gastroesophageal Adenocarcinoma With Moderate Expression of HER2

Who this might be right for
Advanced Gastroesophageal Adenocarcinoma
Chinese PLA General Hospital 42
Testing effectiveness (Phase 2)UnknownNCT04264936
What this trial is testing

RC48-ADC(Antibody Drug Conjugate) and JS001 to Evaluate the Safety and Pharmacokinetics of Subjects With Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Urothelial Carcinoma
Peking University Cancer Hospital & Institute 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05996952
What this trial is testing

RC48-ADC in Adjuvant/Salvage Treatment of HER2 Positive Non-muscle-invasive Bladder Cancer

Who this might be right for
Non-muscle Invasive Bladder Cancer
West China Hospital 77
Testing effectiveness (Phase 2)UnknownNCT05297552
What this trial is testing

RC48-ADC Combined With JS001 For Perioperative Treatment of Muscle-Invasive Bladder Cancer

Who this might be right for
Muscle Invasive Bladder Carcinoma
RemeGen Co., Ltd. 40
Testing effectiveness (Phase 2)UnknownNCT05745740
What this trial is testing

RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 Mutation

Who this might be right for
Non-small Cell Lung Cancer
RemeGen Co., Ltd. 26
Large-scale testing (Phase 3)UnknownNCT04400695
What this trial is testing

RC48-ADC for the Treatment of Locally Advanced or Metastatic Breast Cancer With Low Expression of HER2

Who this might be right for
Breast Cancer
RemeGen Co., Ltd. 366
Testing effectiveness (Phase 2)Study completedNCT04073602
What this trial is testing

RC48-ADC in Subjects With HER2-negative Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Urothelial Carcinoma
RemeGen Co., Ltd. 19
Testing effectiveness (Phase 2)UnknownNCT05785325
What this trial is testing

RC48-ADC Combined With Bevacizumab in HER2-positive Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06574763
What this trial is testing

Neoadjuvant RC48 Plus Carboplatin for HER2-expressing Advanced Ovarian Cancer

Who this might be right for
Ovarian Cancer
Sun Yat-sen University 47
Testing effectiveness (Phase 2)UnknownNCT05135715
What this trial is testing

RC48-ADC in Advanced Melanoma Subjects With HER2 Variant (Mutation, Amplification, Overexpression)

Who this might be right for
Melanoma, Stage IIHER2-positiveAdvanced Melanoma
RemeGen Co., Ltd. 50
Testing effectiveness (Phase 2)Looking for participantsNCT07194005
What this trial is testing

Conversion Therapy With RC48, Sintilimab, and SOX for HER2 1+/2+ Unresectable Gastric Cancer

Who this might be right for
Gastric Cancer
Fudan University 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05980481
What this trial is testing

RC48-ADC Combination Therapies as First-line Treatment in Advanced Metastatic Gastric Cancer

Who this might be right for
Gastric Cancer
RemeGen Co., Ltd. 201
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06492317
What this trial is testing

RC48 Plus AK104 as First-line Treatment for HER2-overexpressing Advanced Gastric Cancer

Who this might be right for
HER2-positive Gastric Cancer
The First Affiliated Hospital of Zhengzhou University 20
Testing effectiveness (Phase 2)UnknownNCT05134519
What this trial is testing

RC48 for Neoadjuvant Chemotherapy of HER2 Positive Breast Cancer

Who this might be right for
Breast CancerHER2-positive Breast Cancer
Xijing Hospital 20
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