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Results for “Radiation-Induced Parotid Gland Hypofunction”

4 trials

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Showing 4 of 4 results

Early research (Phase 1)Study completedNCT04043104
What this trial is testing

Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity of AAV2hAQP1 in Subjects With Radiation-Induced Parotid Gland Hypofunction and Xerostomia

Who this might be right for
Radiation-Induced Parotid Gland HypofunctionXerostomia Due to RadiotherapyHead and Neck Cancer
MeiraGTx UK II Ltd 24
Not applicableActive Not RecruitingNCT05060341
What this trial is testing

Long-Term Follow-Up Study of AAV2hAQP1 for Radiation Induced Xerostomia

Who this might be right for
Radiation-induced Xerostomia
MeiraGTx, LLC 22
Early research (Phase 1)Study completedNCT00372320
What this trial is testing

Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer

Who this might be right for
Parotid Salivary Dysfunction
National Institute of Dental and Craniofacial Research (NIDCR) 17
Early research (Phase 1)Active Not RecruitingNCT02446249
What this trial is testing

Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction

Who this might be right for
Squamous Cell Head and Neck CancerRadiation Induced XerostomiaSalivary Hypofunction
MeiraGTx, LLC 17