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Results for “Rare Malignant Neoplasm”

76 trials

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Showing 20 of 76 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02867592
What this trial is testing

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Who this might be right for
Adrenal Cortical CarcinomaAlveolar Soft Part SarcomaCentral Nervous System Neoplasm+41 more
National Cancer Institute (NCI) 109
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07307053
What this trial is testing

Rare Tumor Focused Platform Study of Innovative Therapies and Technologies (PLATFORM2)

Who this might be right for
Rare Malignant NeoplasmAdvanced Solid TumorsMetastatic Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 600
Large-scale testing (Phase 3)Looking for participantsNCT06988475
What this trial is testing

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

Who this might be right for
Solid TumourHaematological MalignancyMalignant Neoplasm+8 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT06303167
What this trial is testing

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 798
Testing effectiveness (Phase 2)Study completedNCT00154388
What this trial is testing

Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases

Who this might be right for
Life Threatening Diseases
Novartis Pharmaceuticals 185
Large-scale testing (Phase 3)Looking for participantsNCT06947928
What this trial is testing

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

Who this might be right for
Advanced Or Metastatic Merkel Cell Carcinoma
TuHURA Biosciences, Inc. 118
Not applicableApproved For MarketingNCT02961491
What this trial is testing

Expanded Access Program of Ultratrace Iobenguane I131 for Malignant Relapsed/Refractory Pheochromocytoma/Paraganglioma

Who this might be right for
PheochromocytomaParaganglioma
Molecular Insight Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Study completedNCT00790400
What this trial is testing

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)

Who this might be right for
Tuberous Sclerosis Complex (TSC)Lymphangioleiomyomatosis (LAM)
Novartis Pharmaceuticals 118
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Not applicableLooking for participantsNCT04504604
What this trial is testing

TCF-001 TRACK (Target Rare Cancer Knowledge) Study

Who this might be right for
Rare CancersCholangiocarcinomaCancer of Unknown Primary Site
TargetCancer Foundation 400
Testing effectiveness (Phase 2)Temporarily pausedNCT05337735
What this trial is testing

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Who this might be right for
Microsatellite High CancersPeritoneal MesotheliomaExtrapulmonary High Grade+5 more
M.D. Anderson Cancer Center 140
Large-scale testing (Phase 3)Not Yet RecruitingNCT07440290
What this trial is testing

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+16 more
Cancer Research UK 30
Not applicableLooking for participantsNCT07072143
What this trial is testing

An International Study on Pediatric Patients With Rare Tumors.

Who this might be right for
Paraganglioma/ PhaeochromocytomaMelanoma and Other Malignant Neoplasms of SkinGastrointestinal Stromal Tumor (GIST)+11 more
Azienda Ospedaliera di Padova 6,250
Not applicableLooking for participantsNCT07524114
What this trial is testing

Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)

Who this might be right for
Breast CancerLung CancerMelanoma+7 more
University Health Network, Toronto 7,000
Testing effectiveness (Phase 2)Study completedNCT03012620
What this trial is testing

Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types

Who this might be right for
SarcomaOvarian NeoplasmCentral Nervous System Neoplasm+4 more
UNICANCER 334
Testing effectiveness (Phase 2)Study completedNCT02269943
What this trial is testing

Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Neoplasms
Celgene 36
Testing effectiveness (Phase 2)Study completedNCT00002515
What this trial is testing

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Who this might be right for
Childhood Germ Cell TumorExtragonadal Germ Cell TumorHead and Neck Cancer+8 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Study completedNCT03108131
What this trial is testing

Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors

Who this might be right for
Skin Squamous Cell CarcinomaAppendix AdenocarcinomaRare Lesion+9 more
M.D. Anderson Cancer Center 49
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