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Results for “Rare Malignant Neoplasm”

73 trials

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Showing 20 of 73 results

Testing effectiveness (Phase 2)Study completedNCT02923934
What this trial is testing

A Phase II Trial of Ipilimumab and Nivolumab for the Treatment of Rare Cancers

Who this might be right for
Gastrointestinal CancerNeuroendocrine TumoursMalignant Female Reproductive System Neoplasm
Olivia Newton-John Cancer Research Institute 120
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Not applicableStudy completedNCT00007046
What this trial is testing

Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone

Who this might be right for
StenosisHistiocytoma
National Center for Research Resources (NCRR)
Testing effectiveness (Phase 2)Looking for participantsNCT05168566
What this trial is testing

Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Teligene US 99
Not applicableLooking for participantsNCT06250595
What this trial is testing

European Rare Blood Disorders Platform (ENROL)

Who this might be right for
AnemiaBone Marrow FailureBleeding Disorder+9 more
Hospital Universitari Vall d'Hebron Research Institute 37,090
Large-scale testing (Phase 3)Looking for participantsNCT06988475
What this trial is testing

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

Who this might be right for
Solid TumourHaematological MalignancyMalignant Neoplasm+8 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 818
Early research (Phase 1)Active Not RecruitingNCT03478462
What this trial is testing

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma

Who this might be right for
Pediatric Solid TumorPediatric LymphomaPediatric Brain Tumor+5 more
Cellectar Biosciences, Inc. 30
Large-scale testing (Phase 3)Looking for participantsNCT05770037
What this trial is testing

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+8 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT06638931
What this trial is testing

Agnostic Therapy in Rare Solid Tumors

Who this might be right for
Urachal CancerParathyroid CarcinomaFibrolamellar Carcinoma+38 more
Instituto do Cancer do Estado de São Paulo 28
Not applicableActive Not RecruitingNCT03418844
What this trial is testing

Living After a Rare Cancer of the Ovary: Chronic Fatigue, Quality of Life and Late Effects of Chemotherapy

Who this might be right for
Germ Cell TumorSex Cord Stromal TumorMalignant Non-epithelial Ovarian Tumors
Centre Francois Baclesse 268
Large-scale testing (Phase 3)Looking for participantsNCT05722886
What this trial is testing

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Who this might be right for
Haematological MalignancySolid Tumour
Cancer Research UK 825
Testing effectiveness (Phase 2)Temporarily pausedNCT05337735
What this trial is testing

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Who this might be right for
Microsatellite High CancersPeritoneal MesotheliomaExtrapulmonary High Grade+5 more
M.D. Anderson Cancer Center 140
Not applicableLooking for participantsNCT06872853
What this trial is testing

Evaluation of Rare and Complex Tumours of the Thoraco-Abdominal and Soft Tissue District

Who this might be right for
Rare Malignant Neoplasm
IRCCS Azienda Ospedaliero-Universitaria di Bologna 1,100
Testing effectiveness (Phase 2)Active Not RecruitingNCT02721732
What this trial is testing

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Who this might be right for
Advanced Malignant Solid NeoplasmCarcinoma of Unknown PrimaryMetastatic Adrenal Gland Pheochromocytoma+16 more
M.D. Anderson Cancer Center 157
Large-scale testing (Phase 3)Looking for participantsNCT05786716
What this trial is testing

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations

Who this might be right for
Haematological MalignancyColorectal NeoplasmsUrinary Bladder Neoplasm+8 more
Cancer Research UK 30
Not applicableLooking for participantsNCT04151342
What this trial is testing

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Who this might be right for
CancerMalignancies MultipleMalignant Solid Tumor+7 more
University Health Network, Toronto 5,500
Testing effectiveness (Phase 2)Study completedNCT00017680
What this trial is testing

Study of High-Dose Melphalan and Autologous Stem Cell Transplantation in Patients With Primary Light Chain Amyloidosis

Who this might be right for
Amyloidosis
Herbert Irving Comprehensive Cancer Center 25
Testing effectiveness (Phase 2)Study completedNCT03012620
What this trial is testing

Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types

Who this might be right for
SarcomaOvarian NeoplasmCentral Nervous System Neoplasm+4 more
UNICANCER 334
Not applicableLooking for participantsNCT02906943
What this trial is testing

Ontario-wide Cancer TArgeted Nucleic Acid Evaluation

Who this might be right for
Breast CancerLung CancerColorectal Cancer+8 more
University Health Network, Toronto 10,000
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