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Results for “Receptors, Fibroblast Growth Factor”

72 trials

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Showing 20 of 72 results

Large-scale testing (Phase 3)Study completedNCT03410693
What this trial is testing

Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Carcinoma, Transitional Cell
Bayer 175
Testing effectiveness (Phase 2)Study completedNCT04265651
What this trial is testing

Study of Infigratinib in Children With Achondroplasia

Who this might be right for
Achondroplasia
QED Therapeutics, a BridgeBio company 84
Not applicableLooking for participantsNCT06793709
What this trial is testing

A Post-marketing Observational Study of Tasfygo in Participants With Unresectable Biliary Tract Cancer With Fibroblast Growth Factor Receptor 2 (FGFR2) Fusion Gene Positivity Who Progressed After Chemotherapy

Who this might be right for
Biliary Tract Cancer
Eisai Co., Ltd. 60
Early research (Phase 1)Ended earlyNCT02368951
What this trial is testing

Phase I, Dose-escalation Trial of BAY1187982 in Subjects With Advanced Solid Tumors Known to Express Fibroblast Growth Factor Receptor 2 (FGFR2)

Who this might be right for
Medical Oncology
Bayer 20
Testing effectiveness (Phase 2)Ended earlyNCT04604132
What this trial is testing

Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma

Who this might be right for
Gastric Adenocarcinoma
Basilea Pharmaceutica 47
Testing effectiveness (Phase 2)Looking for participantsNCT06511648
What this trial is testing

Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations

Who this might be right for
Muscle-invasive Bladder Cancer
Spanish Oncology Genito-Urinary Group 90
Testing effectiveness (Phase 2)Looking for participantsNCT07292168
What this trial is testing

A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1

Who this might be right for
Renal Cell Carcinoma MetastaticProstate Cancer MetastaticNon-small Cell Lung Cancer Metastatic+2 more
Kidney Cancer Research Bureau 58
Testing effectiveness (Phase 2)Study completedNCT01676714
What this trial is testing

Study of Dovitinib and Biomarkers in Advanced Non-Small Cell Lung Cancer or Advanced Colorectal Cancer

Who this might be right for
Non-Small Cell Lung CancerColorectal Cancer
University of California, Davis 10
Early research (Phase 1)Looking for participantsNCT06625593
What this trial is testing

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BeOne Medicines 168
Early research (Phase 1)Active Not RecruitingNCT04572295
What this trial is testing

E7090 as Monotherapy and in Combination With Other Anticancer Agents in Participants With Estrogen Receptor Positive (ER+) and Human Epidermal Growth Receptor 2 Negative (HER2-) Recurrent/Metastatic Breast Cancer

Who this might be right for
Breast Neoplasms
Eisai Co., Ltd. 51
Large-scale testing (Phase 3)Ended earlyNCT03656536
What this trial is testing

Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

Who this might be right for
Unresectable CholangiocarcinomaMetastatic Cholangiocarcinoma
Incyte Corporation 167
Testing effectiveness (Phase 2)Study completedNCT05325866
What this trial is testing

A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

Who this might be right for
Solid Tumors
Amgen 260
Not applicableStudy completedNCT03816605
What this trial is testing

FGF19 and the Expression of IRS-1 and GLUT-1 in Gestational Diabetes Mellitus

Who this might be right for
Gestational Diabetes Mellitus
First Affiliated Hospital, Sun Yat-Sen University 36
Testing effectiveness (Phase 2)Ended earlyNCT03762122
What this trial is testing

Rogaratinib in Patients With Advanced Pretreated Squamous-cell Non-small Cell Lung Cancer (SQCLC)

Who this might be right for
Squamous-cell Non-small Cell Lung Cancer
Swiss Cancer Institute 15
Large-scale testing (Phase 3)Enrolling By InvitationNCT06873035
What this trial is testing

An Interventional Study of Infigratinib in Children With Hypochondroplasia

Who this might be right for
Hypochondroplasia
QED Therapeutics, a BridgeBio company 24
Testing effectiveness (Phase 2)Study completedNCT02924376
What this trial is testing

Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202)

Who this might be right for
Cholangiocarcinoma
Incyte Corporation 147
Early research (Phase 1)Ended earlyNCT03144661
What this trial is testing

An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies

Who this might be right for
Hepatocellular Carcinoma (HCC)CholangiocarcinomaEsophageal Cancer+3 more
Incyte Corporation 25
Early research (Phase 1)Study completedNCT01962532
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or Lymphoma

Who this might be right for
NeoplasmsLymphomaAdenocarcinoma+1 more
Janssen Research & Development, LLC 19
Testing effectiveness (Phase 2)Study completedNCT02872714
What this trial is testing

Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Urothelial Carcinoma - (FIGHT-201)

Who this might be right for
UC (Urothelial Cancer)
Incyte Corporation 263
Not applicableActive Not RecruitingNCT04035811
What this trial is testing

Prospective Clinical Assessment Study in Children With Achondroplasia (ACH)

Who this might be right for
Achondroplasia
QED Therapeutics, a BridgeBio company 271
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