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Results for “Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes”

47 trials

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Showing 20 of 47 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04734990
What this trial is testing

Seclidemstat and Azacitidine for the Treatment of Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Who this might be right for
Chronic Myelomonocytic Leukemia-0Chronic Myelomonocytic Leukemia-1Chronic Myelomonocytic Leukemia-2+3 more
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Study completedNCT03128359
What this trial is testing

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Who this might be right for
Acute LeukemiaChronic Lymphocytic Leukemia/Small Lymphocytic LymphomaChronic Myelogenous Leukemia, BCR-ABL1 Positive+12 more
City of Hope Medical Center 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT04128748
What this trial is testing

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts More Than 10 Percent of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+4 more
M.D. Anderson Cancer Center 52
Testing effectiveness (Phase 2)WithdrawnNCT04013880
What this trial is testing

ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+3 more
Vanderbilt-Ingram Cancer Center
Early research (Phase 1)Ended earlyNCT03772925
What this trial is testing

Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic SyndromeRefractory Acute Myeloid Leukemia+1 more
National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Ended earlyNCT03537599
What this trial is testing

Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant

Who this might be right for
Minimal Residual DiseaseRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related ChangesRecurrent Adult Acute Myeloid Leukemia+1 more
Sumithira Vasu 4
Early research (Phase 1)Study completedNCT05564650
What this trial is testing

Navitoclax in Relapsed or Refractory High-Risk Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic SyndromeRecurrent Myelodysplastic SyndromeRefractory Myelodysplastic Syndrome
Thomas Jefferson University 6
Testing effectiveness (Phase 2)Ended earlyNCT04160052
What this trial is testing

Venetoclax and Azacitidine for the Treatment of High-Risk Recurrent or Refractory Myelodysplastic Syndrome

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Myelodysplastic Syndrome+2 more
M.D. Anderson Cancer Center 51
Early research (Phase 1)Active Not RecruitingNCT02890329
What this trial is testing

Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Previously Treated Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRecurrent Acute Myeloid Leukemia, Myelodysplasia-Related+5 more
National Cancer Institute (NCI) 54
Early research (Phase 1)Ended earlyNCT04250051
What this trial is testing

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic SyndromeRecurrent Myeloproliferative Neoplasm+5 more
Northwestern University 2
Early research (Phase 1)WithdrawnNCT06572631
What this trial is testing

Multi-antigen Specific CD8+ T Cells With Decitabine and Lymphodepleting Chemotherapy for the Treatment of Patients With Relapsed or Refractory AML or MDS Following an Allogeneic Hematopoietic Cell Transplantation From a Matched Donor

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic SyndromeRefractory Acute Myeloid Leukemia+1 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Study completedNCT00066248
What this trial is testing

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Who this might be right for
Brain TumorCentral Nervous System TumorsCachexia+5 more
University of South Florida 70
Early research (Phase 1)Temporarily pausedNCT03969446
What this trial is testing

Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+3 more
City of Hope Medical Center 54
Testing effectiveness (Phase 2)Ended earlyNCT02392572
What this trial is testing

ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Recurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic Syndrome+3 more
M.D. Anderson Cancer Center 58
Testing effectiveness (Phase 2)Study completedNCT04487106
What this trial is testing

Azacitidine, Venetoclax, and Trametinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Higher-Risk Myelodysplastic Syndrome

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+3 more
M.D. Anderson Cancer Center 21
Early research (Phase 1)Ended earlyNCT03878524
What this trial is testing

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAnatomic Stage IV Breast Cancer AJCC v8Anemia+47 more
OHSU Knight Cancer Institute 2
Testing effectiveness (Phase 2)Ended earlyNCT00949117
What this trial is testing

Cyproheptadine Hydrochloride and Nutritional Supplementation in Treating Young Patients With Weight Loss With Cancer

Who this might be right for
LeukemiaLymphomaMalnutrition+3 more
University of South Florida 9
Testing effectiveness (Phase 2)Looking for participantsNCT06928662
What this trial is testing

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

Who this might be right for
Acute Myeloid LeukemiaAcute Undifferentiated LeukemiaMixed Phenotype Acute Leukemia+11 more
Fred Hutchinson Cancer Center 36
Early research (Phase 1)Looking for participantsNCT06712810
What this trial is testing

Q702 for the Treatment of Patients With Hematologic Malignancies

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmHistiocytic SarcomaMalignant Histiocytosis+34 more
Mayo Clinic 46
Testing effectiveness (Phase 2)Looking for participantsNCT04239157
What this trial is testing

A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Chronic Myelomonocytic Leukemia+3 more
M.D. Anderson Cancer Center 76
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