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Results for “Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes”

46 trials

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Showing 20 of 46 results

Early research (Phase 1)WithdrawnNCT03807063
What this trial is testing

Rivogenlecleucel Donor Lymphocyte Immunotherapy in Treating Patients With Recurrent Blood Cancers After Stem Cell Transplant

Who this might be right for
Acute Bilineal LeukemiaMyelodysplastic/Myeloproliferative NeoplasmMyelodysplastic/Myeloproliferative Neoplasm, Unclassifiable+9 more
Fred Hutchinson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04734990
What this trial is testing

Seclidemstat and Azacitidine for the Treatment of Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Who this might be right for
Chronic Myelomonocytic Leukemia-0Chronic Myelomonocytic Leukemia-1Chronic Myelomonocytic Leukemia-2+3 more
M.D. Anderson Cancer Center 24
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Early research (Phase 1)Active Not RecruitingNCT05146739
What this trial is testing

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

Who this might be right for
Acute Myeloid Leukemia Post Cytotoxic TherapyMyelodysplastic Syndrome Post Cytotoxic TherapyMyeloid Leukemia Associated With Down Syndrome+6 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT06484062
What this trial is testing

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome/Acute Myeloid Leukemia+6 more
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)Looking for participantsNCT03661307
What this trial is testing

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+2 more
M.D. Anderson Cancer Center 73
Large-scale testing (Phase 3)Study completedNCT00008359
What this trial is testing

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

Who this might be right for
Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02684162
What this trial is testing

Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant

Who this might be right for
Acute Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic Syndrome+2 more
M.D. Anderson Cancer Center 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT02861417
What this trial is testing

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmHigh Risk Acute Myeloid LeukemiaHigh Risk Myelodysplastic Syndrome+11 more
M.D. Anderson Cancer Center 204
Early research (Phase 1)Active Not RecruitingNCT04250051
What this trial is testing

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic SyndromeRecurrent Myeloproliferative Neoplasm+2 more
Northwestern University 2
Early research (Phase 1)Study completedNCT03813147
What this trial is testing

Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic Syndrome+2 more
National Cancer Institute (NCI) 12
Early research (Phase 1)Active Not RecruitingNCT02890329
What this trial is testing

Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Previously Treated Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRecurrent Acute Myeloid Leukemia, Myelodysplasia-Related+5 more
National Cancer Institute (NCI) 54
Early research (Phase 1)Looking for participantsNCT03969446
What this trial is testing

Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+3 more
City of Hope Medical Center 54
Early research (Phase 1)Ended earlyNCT03878524
What this trial is testing

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAnatomic Stage IV Breast Cancer AJCC v8Anemia+47 more
OHSU Knight Cancer Institute 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT03953898
What this trial is testing

Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia Post Cytotoxic Therapy+4 more
National Cancer Institute (NCI) 14
Early research (Phase 1)Looking for participantsNCT03816319
What this trial is testing

TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts

Who this might be right for
Myelodysplastic Syndrome With Excess BlastsRecurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic Syndrome+4 more
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)Looking for participantsNCT04128748
What this trial is testing

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts More Than 10 Percent of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+4 more
M.D. Anderson Cancer Center 52
Testing effectiveness (Phase 2)Ended earlyNCT03146871
What this trial is testing

Recombinant EphB4-HSA Fusion Protein and Azacitidine or Decitabine for Relapsed or Refractory Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Patients Previously Treated With a Hypomethylating Agent

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic Syndrome+2 more
University of Southern California 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT02530463
What this trial is testing

Nivolumab and/or Ipilimumab With or Without Azacitidine in Treating Patients With Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromeRecurrent Myelodysplastic Syndrome
M.D. Anderson Cancer Center 99
Testing effectiveness (Phase 2)Ended earlyNCT04874194
What this trial is testing

Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Myeloid Leukemia+4 more
M.D. Anderson Cancer Center 24
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