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Results for “Recurrent Diffuse Intrinsic Pontine Glioma”

41 trials

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Showing 20 of 41 results

Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT04758533
What this trial is testing

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy

Who this might be right for
Diffuse Intrinsic Pontine GliomaMedulloblastoma, Childhood, Recurrent
Hospital Infantil Universitario Niño Jesús, Madrid, Spain 13
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Testing effectiveness (Phase 2)Study completedNCT00600054
What this trial is testing

Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma

Who this might be right for
Recurrent Diffuse Pontine Gliomas
YM BioSciences 44
Testing effectiveness (Phase 2)Study completedNCT03257631
What this trial is testing

Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Who this might be right for
Central Nervous System NeoplasmsMedulloblastoma
Celgene 53
Early research (Phase 1)Looking for participantsNCT07664176
What this trial is testing

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

Who this might be right for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine GliomaHigh Grade GliomasMedulloblastoma Recurrent+3 more
Children's National Research Institute 30
Early research (Phase 1)Not Yet RecruitingNCT07331064
What this trial is testing

Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor

Who this might be right for
High Grade GliomasAtypical Teratoid Rhabdoid Tumors (ATRT)Diffuse Midline Glioma+2 more
Sarah Rumler 15
Early research (Phase 1)Active Not RecruitingNCT03598244
What this trial is testing

Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Who this might be right for
Recurrent Diffuse Intrinsic Pontine GliomaRecurrent Malignant GliomaRecurrent Medulloblastoma+5 more
National Cancer Institute (NCI) 41
Testing effectiveness (Phase 2)Looking for participantsNCT04870944
What this trial is testing

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Who this might be right for
Diffuse Midline Glioma, H3 K27-AlteredMetastatic Malignant Neoplasm in the Central Nervous SystemRecurrent Diffuse Intrinsic Pontine Glioma+7 more
Children's Oncology Group 63
Testing effectiveness (Phase 2)Ended earlyNCT01517776
What this trial is testing

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents

Who this might be right for
Gliomas
Martin-Luther-Universität Halle-Wittenberg 28
Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Testing effectiveness (Phase 2)Looking for participantsNCT05009992
What this trial is testing

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantRecurrent Diffuse Intrinsic Pontine Glioma+3 more
University of California, San Francisco 360
Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Early research (Phase 1)Ended earlyNCT04341311
What this trial is testing

Phase I Study of Marizomib + Panobinostat for Children With DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaPediatric Brainstem GliomaPediatric Brainstem Gliosarcoma, Recurrent+3 more
Dana-Farber Cancer Institute 4
Testing effectiveness (Phase 2)Ended earlyNCT01836549
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAstrocytoma, Grade II+6 more
Pediatric Brain Tumor Consortium 43
Early research (Phase 1)Not Yet RecruitingNCT06946680
What this trial is testing

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)

Who this might be right for
High-grade GliomaDiffuse Intrinsic Pontine Glioma
University of Florida 24
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Early research (Phase 1)Ended earlyNCT03416530
What this trial is testing

ONC201 in Pediatric H3 K27M Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGlioma, Malignant
Jazz Pharmaceuticals 134
Early research (Phase 1)Study completedNCT02644291
What this trial is testing

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Who this might be right for
MedulloblastomaAstrocytoma, Grade IIIGlioblastoma+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 16
Testing effectiveness (Phase 2)Temporarily pausedNCT06639607
What this trial is testing

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Who this might be right for
Diffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more
Washington University School of Medicine 68
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