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Results for “Recurrent Diffuse Pontine Gliomas”

38 trials

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Showing 20 of 38 results

Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Early research (Phase 1)Study completedNCT02644291
What this trial is testing

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Who this might be right for
MedulloblastomaAstrocytoma, Grade IIIGlioblastoma+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 16
Not applicableStudy completedNCT03126266
What this trial is testing

Re-Irradiation of Progressive or Recurrent DIPG

Who this might be right for
Recurrent or Progressive Diffuse Intrinsic Pontine Glioma
University of Calgary 27
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Testing effectiveness (Phase 2)Ended earlyNCT01517776
What this trial is testing

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents

Who this might be right for
Gliomas
Martin-Luther-Universität Halle-Wittenberg 28
Early research (Phase 1)Active Not RecruitingNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32
Not applicableActive Not RecruitingNCT03033992
What this trial is testing

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Who this might be right for
Malignant GliomaEpendymomaDiffuse Intrinsic Pontine Glioma
Children's Oncology Group 80
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06639607
What this trial is testing

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Who this might be right for
Diffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more
Washington University School of Medicine 68
Testing effectiveness (Phase 2)Study completedNCT01469247
What this trial is testing

Diffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT)

Who this might be right for
Brain Cancer
M.D. Anderson Cancer Center 12
Testing effectiveness (Phase 2)Looking for participantsNCT04870944
What this trial is testing

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Who this might be right for
Diffuse Midline Glioma, H3 K27-AlteredMetastatic Malignant Neoplasm in the Central Nervous SystemRecurrent Diffuse Intrinsic Pontine Glioma+7 more
Children's Oncology Group 63
Testing effectiveness (Phase 2)Study completedNCT03257631
What this trial is testing

Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Who this might be right for
Central Nervous System NeoplasmsMedulloblastoma
Celgene 53
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Early research (Phase 1)Active Not RecruitingNCT04837547
What this trial is testing

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

Who this might be right for
NeuroblastomaDiffuse Intrinsic Pontine Glioma
University of Florida 24
Testing effectiveness (Phase 2)Study completedNCT00600054
What this trial is testing

Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma

Who this might be right for
Recurrent Diffuse Pontine Gliomas
YM BioSciences 44
Early research (Phase 1)Ended earlyNCT04341311
What this trial is testing

Phase I Study of Marizomib + Panobinostat for Children With DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaPediatric Brainstem GliomaPediatric Brainstem Gliosarcoma, Recurrent+3 more
Dana-Farber Cancer Institute 4
Early research (Phase 1)Ended earlyNCT03416530
What this trial is testing

ONC201 in Pediatric H3 K27M Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGlioma, Malignant
Jazz Pharmaceuticals 134
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Early research (Phase 1)Active Not RecruitingNCT03598244
What this trial is testing

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Who this might be right for
Recurrent Diffuse Intrinsic Pontine GliomaRecurrent Malignant GliomaRecurrent Medulloblastoma+5 more
National Cancer Institute (NCI) 41
Early research (Phase 1)Study completedNCT02444546
What this trial is testing

Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

Who this might be right for
Childhood AstrocytomaChildhood Atypical Teratoid/Rhabdoid TumorDiffuse Intrinsic Pontine Glioma+7 more
Mayo Clinic 6
Testing effectiveness (Phase 2)Looking for participantsNCT05009992
What this trial is testing

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantRecurrent Diffuse Intrinsic Pontine Glioma+3 more
University of California, San Francisco 360
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