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Results for “Recurrent Glioblastoma, IDH-Wildtype”

46 trials

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Showing 20 of 46 results

Testing effectiveness (Phase 2)Looking for participantsNCT07416188
What this trial is testing

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

Who this might be right for
Recurrent GlioblastomaGlioblastoma IDH (Isocitrate Dehydrogenase) WildtypeRelapsed Cancer+12 more
National Institute of Neurological Disorders and Stroke (NINDS) 40
Testing effectiveness (Phase 2)Looking for participantsNCT07318818
What this trial is testing

A Clinical Trial of P134 Cells in Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma IDH Wildtype
Tasly Pharmaceutical Group Co., Ltd 26
Early research (Phase 1)Not Yet RecruitingNCT07385846
What this trial is testing

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

Who this might be right for
GlioblastomaMismatch Repair Deficiency
Jennifer Leddon 8
Testing effectiveness (Phase 2)WithdrawnNCT05218408
What this trial is testing

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type

Who this might be right for
Astrocytoma, Grade IVGlioblastomaGiant Cell Glioblastoma+1 more
Celularity Incorporated
Not applicableLooking for participantsNCT06430424
What this trial is testing

Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma

Who this might be right for
Relapsed CancerGlioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
University Hospital, Bordeaux 40
Very early researchActive Not RecruitingNCT06824662
What this trial is testing

Phase 0 With Expansion Phase Clinical Trial of Quisinostat Plus Radiotherapy in Newly-diagnosed and Recurrent Grade 4 IDH-Wildtype Glioblastomas

Who this might be right for
Glioblastoma WHO Grade IV
Nader Sanai 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04729959
What this trial is testing

Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma

Who this might be right for
Diffuse Astrocytoma, IDH-WildtypeRecurrent Glioblastoma
National Cancer Institute (NCI) 61
Early research (Phase 1)Not Yet RecruitingNCT07422363
What this trial is testing

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent GliosarcomaRecurrent WHO Grade 4 Glioma
National Cancer Institute (NCI) 30
Not applicableLooking for participantsNCT06283927
What this trial is testing

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

Who this might be right for
GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+5 more
Jasper Gerritsen 464
Large-scale testing (Phase 3)Not Yet RecruitingNCT07349693
What this trial is testing

Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-Wildtype
Everfront Biotech Co., Ltd. 175
Very early researchLooking for participantsNCT06552260
What this trial is testing

A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

Who this might be right for
GlioblastomaRecurrent GlioblastomaBrain Tumor
Ugonma Chukwueke 27
Early research (Phase 1)Looking for participantsNCT07089641
What this trial is testing

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

Who this might be right for
GlioblastomaGlioblastoma, IDH-WildtypeGliosarcoma+3 more
Jonsson Comprehensive Cancer Center 50
Testing effectiveness (Phase 2)Looking for participantsNCT05465954
What this trial is testing

Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma

Who this might be right for
High Grade Astrocytic TumorRecurrent Glioblastoma, IDH-WildtypeRecurrent Gliosarcoma
Mayo Clinic 54
Testing effectiveness (Phase 2)WithdrawnNCT06328036
What this trial is testing

Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-Wildtype
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Active Not RecruitingNCT03423628
What this trial is testing

Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Who this might be right for
Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca 159
Testing effectiveness (Phase 2)Study completedNCT00179907
What this trial is testing

A Phase I/II Study of the Photon Radiosurgery System

Who this might be right for
Brain Tumor, RecurrentGlioblastoma Multiforme
Ann & Robert H Lurie Children's Hospital of Chicago 35
Early research (Phase 1)Looking for participantsNCT07733674
What this trial is testing

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

Who this might be right for
Glioblastoma Multiforme (GBM)Pancreatic Ductal Adenocarcinoma (PDAC)
Radiomedix, Inc. 20
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT04145115
What this trial is testing

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more
National Cancer Institute (NCI) 37
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