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Results for “Recurrent Glioblastoma, IDH-Wildtype”

41 trials

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Showing 20 of 41 results

Early research (Phase 1)Looking for participantsNCT03423628
What this trial is testing

Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Who this might be right for
Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca 180
Early research (Phase 1)Ended earlyNCT04782609
What this trial is testing

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma

Who this might be right for
Recurrent Glioblastoma Multiforme (GBM)Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype AstrocytomaGrade 3 or 4 Astrocytoma+1 more
Samus Therapeutics, Inc. 7
Early research (Phase 1)Looking for participantsNCT07544992
What this trial is testing

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma, IDH-Wildtype
City of Hope Medical Center 24
Very early researchActive Not RecruitingNCT06824662
What this trial is testing

Phase 0 With Expansion Phase Clinical Trial of Quisinostat Plus Radiotherapy in Newly-diagnosed and Recurrent Grade 4 IDH-Wildtype Glioblastomas

Who this might be right for
Glioblastoma WHO Grade IV
Nader Sanai 30
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Very early researchEnrolling By InvitationNCT07520214
What this trial is testing

Clinical Study on the Safety and Immunogenicity of Specific Cancer Vaccines in Preventing Recurrence of Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeGlioblastom WHO Grade 4
Beijing Neurosurgical Institute 9
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Early research (Phase 1)Not Yet RecruitingNCT07422363
What this trial is testing

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent GliosarcomaRecurrent WHO Grade 4 Glioma
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07620548
What this trial is testing

Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas

Who this might be right for
GlioblastomaGlioblastoma, IDH-wildtypeGlioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Washington University School of Medicine 99
Not applicableLooking for participantsNCT06430424
What this trial is testing

Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma

Who this might be right for
Relapsed CancerGlioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
University Hospital, Bordeaux 40
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Not applicableLooking for participantsNCT06283927
What this trial is testing

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

Who this might be right for
GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+5 more
Jasper Gerritsen 464
Early research (Phase 1)Not Yet RecruitingNCT07385846
What this trial is testing

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

Who this might be right for
GlioblastomaMismatch Repair Deficiency
Jennifer Leddon 8
Testing effectiveness (Phase 2)WithdrawnNCT06328036
What this trial is testing

Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-Wildtype
National Cancer Institute (NCI)
Very early researchLooking for participantsNCT06552260
What this trial is testing

A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

Who this might be right for
GlioblastomaRecurrent GlioblastomaBrain Tumor
Ugonma Chukwueke 27
Not applicableStudy completedNCT05759195
What this trial is testing

Biomolecular Analysis for Predicting Response to Regorafenib

Who this might be right for
GlioblastomaGlioblastoma, IDH-wildtype
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 53
Early research (Phase 1)Looking for participantsNCT06455605
What this trial is testing

D2C7-IT + 2141-V11 Combination Post-resection in rGBM

Who this might be right for
Recurrent Glioblastoma IDH Wildtype
Darell Bigner 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT04528680
What this trial is testing

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma

Who this might be right for
GlioblastomaGliosarcomaGBM+3 more
Northwestern University 57
Not applicableLooking for participantsNCT06273176
What this trial is testing

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

Who this might be right for
Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme of Brain+6 more
Erasmus Medical Center 225
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06258018
What this trial is testing

Niraparib and Temozolomide in Patients Glioblastoma

Who this might be right for
Glioma, Malignant
Armando Santoro, MD 86
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