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Results for “Recurrent Grade 4 Glioma”

91 trials

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Showing 20 of 91 results

Early research (Phase 1)Looking for participantsNCT07755397
What this trial is testing

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

Who this might be right for
NSCLC Patients With EGFR Activating MutationAdenoid Cystic Carcinoma MetastaticAdenoid Cystic Carcinoma of the Head and Neck
Jubilant Therapeutics India Limited 30
Testing effectiveness (Phase 2)Ended earlyNCT01011231
What this trial is testing

Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Imaging (MRI) Spectroscopy for Recurrent Glioma

Who this might be right for
Glioblastoma
University of California, San Francisco 1
Early research (Phase 1)Active Not RecruitingNCT04606316
What this trial is testing

Surgical Nivolumab And Ipilimumab For Recurrent GBM

Who this might be right for
GlioblastomaGBMGlioblastoma Multiforme+1 more
Patrick Wen, MD 63
Testing effectiveness (Phase 2)Ended earlyNCT04915404
What this trial is testing

Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)

Who this might be right for
Recurrent Glioblastoma Multiforme
WPD Pharmaceuticals Sp. z o.o. 5
Early research (Phase 1)Study completedNCT02709226
What this trial is testing

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Who this might be right for
Astrocytoma, Grade IVGiant Cell GlioblastomaGlioblastoma Multiforme+1 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Ended earlyNCT01966809
What this trial is testing

Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas

Who this might be right for
Brain Tumor, Recurrent
Harry T Whelan, MD 1
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Very early researchNot Yet RecruitingNCT07384390
What this trial is testing

TH-CAR-027 for Grade 4 Gliomas

Who this might be right for
R/R Grade 4 Glioma
Shanghai Tongji Hospital, Tongji University School of Medicine 21
Early research (Phase 1)Study completedNCT00006368
What this trial is testing

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerGastrointestinal Carcinoid Tumor+5 more
Novartis Pharmaceuticals 60
Early research (Phase 1)Study completedNCT01240460
What this trial is testing

Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection

Who this might be right for
GlioblastomaAstrocytoma, Grade IV
Sanofi 40
Testing effectiveness (Phase 2)Study completedNCT00104091
What this trial is testing

Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors

Who this might be right for
Glioblastoma Multiforme
Teva Branded Pharmaceutical Products R&D, Inc. 56
Early research (Phase 1)Enrolling By InvitationNCT06896110
What this trial is testing

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

Who this might be right for
Glioblastoma (GBM)Diffuse Midline Glioma (DMG)Astrocytoma, IDH-Mutant, Grade 4+2 more
Andrew P. Groves 34
Early research (Phase 1)Study completedNCT01172964
What this trial is testing

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

Who this might be right for
Adult Anaplastic AstrocytomaRecurrent Grade III GliomaRecurrent Grade IV Glioma+9 more
City of Hope Medical Center 15
Very early researchActive Not RecruitingNCT05182905
What this trial is testing

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Who this might be right for
GlioblastomaGliomaGlioblastoma Multiforme+1 more
Nader Sanai 97
Very early researchLooking for participantsNCT07268053
What this trial is testing

A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases

Who this might be right for
Glioblastoma (GBM)Brain Metastasases
Nader Sanai 15
Testing effectiveness (Phase 2)Study completedNCT00071539
What this trial is testing

Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors

Who this might be right for
Recurrent Glioblastoma Multiforme
Teva Branded Pharmaceutical Products R&D, Inc. 56
Early research (Phase 1)Looking for participantsNCT07560865
What this trial is testing

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

Who this might be right for
AstrocytomaGlioblastomaProgressive Disease
Masonic Cancer Center, University of Minnesota 9
Early research (Phase 1)Looking for participantsNCT07089641
What this trial is testing

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

Who this might be right for
GlioblastomaGlioblastoma, IDH-WildtypeGliosarcoma+3 more
Jonsson Comprehensive Cancer Center 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05859334
What this trial is testing

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

Who this might be right for
Recurrent GliomaRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
National Cancer Institute (NCI) 30
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